Browsing by Author "Mancebo Moreno, Gemma"

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  • ALCAM shedding at the invasive front of the tumor is a marker of myometrial infiltration and promotes invasion in endometrioid endometrial cancer
    Devis, Laura; Martínez-García, Elena; Moiola, Cristian P.; Quiles, Maria Teresa; Arbós, Maria Antonia; Stirbat, Tomita Vasilica; Brochard-Wyart, Françoise; García, Ángel; Alonso-Alconada, Lorena; Abal, Miguel; Díaz-Feijoo, Berta; Thomas, William; Dufour, Sylvie; Mancebo Moreno, Gemma; Alameda Quitllet, Francisco; Reventós, Jaume; Gil-Moreno, Antonio; Colas, Eva (Impact Journal, 2018)
    Endometrial cancer (EC) is the sixth deadliest cancer in women. The depth of myometrial invasion is one of the most important prognostic factors, being directly associated with tumor recurrence and mortality. In this study, ...
  • Gynecologic cancer surveillance in the era of SARS-CoV-2 (COVID-19)
    Mancebo Moreno, Gemma; Solé-Sedeño, Josep Maria; Membrive, Ismael; Taus García, Álvaro; Castells Zaragoza, Marta; Serrano, Laia; Carreras Collado, Ramón; Miralpeix, E. (BMJ Publishing Group, 2021)
    The SARS-CoV-2 (COVID-19) pandemic has significantly impacted the management of patients with gynecologic cancers. Many centers have reduced access to routine visits to avoid crowded waiting areas and specially to reduce ...
  • Impact of prehabilitation during neoadjuvant chemotherapy and interval cytoreductive surgery on ovarian cancer patients: a pilot study
    Miralpeix, Ester; Solé-Sedeño, Josep Maria; Rodriguez-Cosmen, Cristina; Taus García, Álvaro; Muns, Maria Dolors; Fabregó, Berta; Mancebo Moreno, Gemma (BioMed Central, 2022)
    Background: Cytoreductive surgery followed by systemic chemotherapy is the standard of treatment in advanced ovarian cancer where feasible. Neoadjuvant chemotherapy (NACT) followed by surgery is applicable where upfront ...
  • L1CAM expression in endometrial carcinomas: an ENITEC collaboration study
    van der Putten, Louis J.M.; Mancebo Moreno, Gemma; Alameda Quitllet, Francisco; Pijnenborg, Johanna M.A. (Nature Publishing Group, 2016)
    BACKGROUND: Identification of aggressive endometrioid endometrial carcinomas (EECs) and non-endometrioid carcinomas (NEECs) is essential to improve outcome. L1 cell adhesion molecule (L1CAM) expression is a strong prognostic ...
  • Preoperative risk stratification in endometrial cancer (ENDORISK) by a Bayesian network model: a development and validation study
    Reijnen, Casper; Mancebo Moreno, Gemma; Pijnenborg, Johanna M.A. (Public Library of Science (PLoS), 2020)
    Background: Bayesian networks (BNs) are machine-learning-based computational models that visualize causal relationships and provide insight into the processes underlying disease progression, closely resembling clinical ...
  • Prognostic impact of CD133 expression in Endometrial Cancer Patients
    Mancebo Moreno, Gemma; Solé-Sedeño, Josep Maria; Pino, O.; Miralpeix, E.; Mojal, Sergio; Garrigos, L.; Lloveras Rubio, Belen; Navarro Medrano, Pilar; Gibert, Joan; Lorenzo Perez, Marta; Aran, Iris; Carreras Collado, Ramón; Alameda Quitllet, Francisco (Nature Publishing Group, 2017)
    To assess the impact of CD133 expression on the prognosis of endometrioid endometrial carcinoma (EEC). We retrospectively assessed CD133 expression in tissue microarray of 116 surgically treated FIGO I-III EEC. Tumors with ...
  • The amount of preoperative endometrial tissue surface in relation to final endometrial cancer classification
    Vrede, Stephanie W.; Hulsman, Anneloes M.C.; Reijnen, Casper; van de Vijver, Koen K.B.T.; Colas, Eva; Mancebo Moreno, Gemma; Moiola, Cristian Pablo; Gil-Moreno, Antonio; Huvila, Jutta; Koskas, Martin; Weinberger, Vit; Minář, Luboš; Jandáková, Eva; Santacana, Maria; Matias-Guiu, Xavier; Amant, Frédéric; Snijders, Marc P.L.M.; Küsters-Vandevelde, Heidi V.N.; ENITEC-Consortium; Bulten, Johan Hans; Pijnenborg, Johanna M.A. (Elsevier, 2022)
    Objective: To evaluate whether the amount of preoperative endometrial tissue surface is related to the degree of concordance with final low- and high-grade endometrial cancer (EC). In addition, to determine whether discordance ...
  • The cutoff for estrogen and progesterone receptor expression in endometrial cancer revisited: a european network for individualized treatment of endometrial cancer collaboration study
    van Weelden, Willem Jan; Mancebo Moreno, Gemma; Amant, Frédéric; ENITEC-Consortium (Elsevier, 2021)
    There is no consensus on the cutoff for positivity of estrogen receptor (ER) and progesterone receptor (PR) in endometrial cancer (EC). Therefore, we determined the cutoff value for ER and PR expression with the strongest ...