Browsing by Author "Maitre, Léa"

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  • Vrijheid, Martine; Basagaña Flores, Xavier; González, Juan Ramón; Porcel, Joana; Bustamante Pineda, Mariona; Casas Sanahuja, Maribel; Dadvand, Payam; Fossati, Serena; Guxens Junyent, Mònica; Maitre, Léa; Nieuwenhuijsen, Mark J.; Ortiz, Rodney; Stratakis, Nikos; Sunyer Deu, Jordi; Slama, Rémy (Wolters Kluwer (LWW), 2021)
    Early life stages are vulnerable to environmental hazards and present important windows of opportunity for lifelong disease prevention. This makes early life a relevant starting point for exposome studies. The Advancing ...
  • Santos, Susana; Maitre, Léa; Warembourg, Charline; Agier, Lydiane; Richiardi, Lorenzo; Basagaña Flores, Xavier; Vrijheid, Martine (Springer, 2020)
    The exposome represents the totality of life course environmental exposures (including lifestyle and other non-genetic factors), from the prenatal period onwards. This holistic concept of exposure provides a new framework ...
  • Maitre, Léa; Lau, Chung-Ho E.; Vizcaino, Esther; Robinson, Oliver; Casas Sanahuja, Maribel; Siskos, Alexandros P.; Want, Elizabeth J.; Athersuch, Toby J.; Slama, Rémy; Vrijheid, Martine; Keun, Hector C.; Coen, Muireann (Nature Research, 2017)
    The application of metabolic phenotyping in clinical and epidemiological studies is limited by a poor understanding of inter-individual, intra-individual and temporal variability in metabolic phenotypes. Using 1H NMR ...
  • Neumann, Alexander; Alemany, Silvia; González, Juan Ramón; Julvez, Jordi; Maitre, Léa; Sunyer Deu, Jordi; Guxens Junyent, Mònica; Tiemeier, Henning (Nature Research, 2020)
    Attention-deficit and hyperactivity disorder (ADHD) is a common childhood disorder with a substantial genetic component. However, the extent to which epigenetic mechanisms play a role in the etiology of the disorder is ...
  • Brennan Kearns, Pavla; van den Dries, Michiel; Julvez, Jordi; Kampouri, Mariza; López Vicente, Mònica, 1988-; Maitre, Léa; Philippat, Claire; Haug, Line Småstuen; Vafeiadi, Marina, 1983-; Thomsen, Cathrine; Yang, Tiffany C.; Vrijheid, Martine; Tiemeier, Henning; Guxens Junyent, Mònica (Elsevier, 2024)
    Chemical exposures often occur in mixtures and exposures during pregnancy may lead to adverse effects on the fetal brain, potentially reducing lower cognitive abilities and fine motor function of the child. We investigated ...
  • Stratakis, Nikos; Borràs, Eva; Sabidó Aguadé, Eduard, 1981-; Basagaña Flores, Xavier; Bustamante Pineda, Mariona; Casas Sanahuja, Maribel; Fossati, Serena; González Ruiz, Juan Ramón; Maitre, Léa; Urquiza, José M.; Vrijheid, Martine; Chatzi, Leda (JAMA Network, 2020)
    IMPORTANCE: The balance of mercury risk and nutritional benefit from fish intake during pregnancy for the metabolic health of offspring to date is unknown. OBJECTIVE: To assess the associations of fish intake and mercury ...
  • Midya, Vishal; Andrušaitytė, Sandra; Basagaña Flores, Xavier; Casas Sanahuja, Maribel; Fossati, Serena; Gražulevičienė, Regina; Maitre, Léa; Urquiza, José M.; Vrijheid, Martine; Valvi, Damaskini, 1983- (American Medical Association, 2022)
    Importance: Prenatal exposures to endocrine-disrupting chemicals (EDCs) may increase the risk for liver injury in children; however, human evidence is scarce, and previous studies have not considered potential EDC-mixture ...
  • Guillien, Alicia; Casas Sanahuja, Maribel; Castro, Montserrat de; Maitre, Léa; Nieuwenhuijsen, Mark J.; Urquiza, José M.; Vrijheid, Martine; Basagaña Flores, Xavier; Siroux, Valérie (Elsevier, 2024)
    Introduction: Previous studies identified some environmental and lifestyle factors independently associated with children respiratory health, but few focused on exposure mixture effects. This study aimed at identifying, ...
  • Robinson, Oliver; Lau, Chung-Ho E.; Joo, Sungyeon; Andrušaitytė, Sandra; Borràs, Eva; Prado Bert, Paula de; Chatzi, Lida Vaia; Keun, Hector C.; Gražulevičienė, Regina; Gutzkow, Kristine B.; Maitre, Léa; Martens, Dries S.; Sabidó Aguadé, Eduard, 1981-; Siroux, Valérie; Urquiza, José M.; Vafeiadi, Marina, 1983-; Wright, John; Nawrot, Tim S.; Bustamante Pineda, Mariona; Vrijheid, Martine (eLife, 2023)
    Background: While biological age in adults is often understood as representing general health and resilience, the conceptual interpretation of accelerated biological age in children and its relationship to development ...
  • Anguita Ruiz, Augusto; Amine, Ines; Stratakis, Nikos; Maitre, Léa; Júlvez Calvo, Jordi; Urquiza, José M.; Luo, Chongliang; Nieuwenhuijsen, Mark J.; Thomsen, Cathrine; Gražulevičienė, Regina; Heude, Barbara; McEachan, Rosemary R.C.; Vafeiadi, Marina, 1983-; Chatzi, Leda; Wright, John; Yang, Tiffany C.; Slama, Rémy; Siroux, Valérie; Vrijheid, Martine; Basagaña Flores, Xavier (Elsevier, 2023)
    Outcome-wide analysis can offer several benefits, including increased power to detect weak signals and the ability to identify exposures with multiple effects on health, which may be good targets for preventive measures. ...
  • Dypås, Lene B.; Duale, Nur; Olsen, Ann-Karin; Bustamante Pineda, Mariona; Maitre, Léa; Escaramís, Geòrgia; Júlvez Calvo, Jordi; Aguilar Lacasaña, Sofía; Andrušaitytė, Sandra; Casas Sanahuja, Maribel; Vafeiadi, Marina, 1983-; Gražulevičienė, Regina; Heude, Barbara; Lepeule, Johanna; Urquiza, José M.; Wright, John; Yang, Tiffany C.; Vrijheid, Martine; Gützkow, Kristine B. (BioMed Central, 2023)
    Background: Attention-deficit/hyperactivity disorder (ADHD) is a prevalent and highly heritable neurodevelopmental disorder of major societal concern. Diagnosis can be challenging and there are large knowledge gaps regarding ...
  • Balcells Nadal, Cristina; Xu, Yitao; Gil Solsona, Rubén; Maitre, Léa; Gago Ferrero, Pablo; Keun, Hector C. (Elsevier, 2024)
    The aetiology of every human disease lies in a combination of genetic and environmental factors, each contributing in varying proportions. While genomics investigates the former, a comparable holistic paradigm was proposed ...
  • Ruiz Castell, María de la Concepción, 1981-; Le Coroller, Gwenaëlle; Pexaras, Achilleas; Ciprián, Giovana M.; Fagherazzi, Guy; Bohn, Torsten; Maitre, Léa; Sunyer Deu, Jordi; Appenzeller, Brice M. R. (Elsevier, 2023)
    Throughout life individuals are exposed to a large array of diverse environmental exposures (exposome). Hair analyses can assess chronic exposure to a large number of chemicals with less intra-variability than urine and ...
  • Fabbri, Lorenzo; Garlantézec, Ronan; Audouze, Karine; Bustamante Pineda, Mariona; Carracedo, Ángel; Chatzi, Leda; González, Juan Ramón; Gražulevičienė, Regina; Keun, Hector C.; Lau, Chung-Ho E.; Sabidó, Eduard; Siskos, Alexandros P.; Slama, Rémy; Thomsen, Cathrine; Wright, John; Yuan, Wen Lun; Casas, Maribel; Vrijheid, Martine; Maitre, Léa (Elsevier, 2023)
    Individuals are exposed to environmental pollutants with endocrine disrupting activity (endocrine disruptors, EDCs) and the early stages of life are particularly susceptible to these exposures. Previous studies have focused ...
  • Handakas, Evangelos; Keski-Rahkonen, Pekka; Chatzi, Leda; Alfano, Rossella; Roumeliotaki, Theano; Plusquin, Michelle; Maitre, Léa; Richiardi, Lorenzo; Brescianini, Sonia; Scalbert, Augustin; Robinot, Nivonirina; Nawrot, Tim S.; Sassi, Franco; Vrijheid, Martine; Vineis, Paolo; Robinson, Oliver (Nature Research, 2021)
    Introduction: Metabolomics may identify biological pathways predisposing children to the risk of overweight and obesity. In this study, we have investigated the cord blood metabolic signatures of rapid growth in infancy ...
  • Alfano, Rossella; Plusquin, Michelle; Robinson, Oliver; Brescianini, Sonia; Chatzi, Leda; Keski-Rahkonen, Pekka; Handakas, Evangelos; Maitre, Léa; Nawrot, Tim S.; Robinot, Nivonirina; Roumeliotaki, Theano; Sassi, Franco; Scalbert, Augustin; Vrijheid, Martine; Vineis, Paolo; Richiardi, Lorenzo; Zugna, Daniela (Nature Research, 2022)
    Background: The mechanisms underlying childhood overweight and obesity are poorly known. Here, we investigated the direct and indirect effects of different prenatal exposures on offspring rapid postnatal growth and overweight ...
  • Lau, Chung-Ho E.; Maitre, Léa; Urquiza, José M.; Casas Sanahuja, Maribel; Vrijheid, Martine; Coen, Muireann (BioMed Central, 2018)
    Background: Environment and diet in early life can affect development and health throughout the life course. Metabolic phenotyping of urine and serum represents a complementary systems-wide approach to elucidate ...
  • Papadopoulou, Eleni, 1985-; Haug, Line Småstuen; Sakhi, Amrit Kaur; Andrušaitytė, Sandra; Basagaña Flores, Xavier; Brantsaeter, Anne Lise; Casas Sanahuja, Maribel; Fernández-Barrés, Sílvia; Gražulevičienė, Regina; Knutsen, Helle Katrine; Maitre, Léa; Meltzer, Helle Margrete; McEachan, Rosemary R.C.; Roumeliotaki, Theano; Slama, Rémy; Vafeiadi, Marina, 1983-; Wright, John; Vrijheid, Martine; Thomsen, Cathrine; Chatzi, Leda (National Institute of Environmental Health Sciences, 2019)
    Background: Pregnant women and children are especially vulnerable to exposures to food contaminants, and a balanced diet during these periods is critical for optimal nutritional status. Objectives: Our objective was to ...
  • Lozano, Manuel; McEachan, Rosemary R.C.; Wright, John; Yang, Tiffany C.; Dow, Courtney; Kadawathagedara, Manik; Lepeule, Johanna; Bustamante Pineda, Mariona; Maitre, Léa; Vrijheid, Martine; Brantsaeter, Anne Lise; Meltzer, Helle Margrete; Bempi, Vasiliki; Roumeliotaki, Theano; Thomsen, Cathrine; Nawrot, Tim S.; Broberg, Karin; Llop, Sabrina (Elsevier, 2024)
    Background: Telomere length (TL) and mitochondrial function expressed as mitochondrial DNA copy number (mtDNAcn) are biomarkers of aging and oxidative stress and inflammation, respectively. Methylmercury (MeHg), a common ...
  • Julvez, Jordi; López Vicente, Mònica, 1988-; Warembourg, Charline; Maitre, Léa; Philippat, Claire; Gützkow, Kristine B.; Guxens Junyent, Mònica; Evandt, Jorunn; Andrušaitytė, Sandra; Burgaleta Díaz, Miguel, 1981-; Casas Sanahuja, Maribel; Chatzi, Leda; de Castro, Montserrat; Donaire González, David; Gražulevičienė, Regina; Hernandez-Ferrer, Carles, 1987-; Heude, Barbara; McEachan, Rosie; Mon-Williams, Mark; Nieuwenhuijsen, Mark J.; Robinson, Oliver; Sakhi, Amrit Kaur; Sebastián Gallés, Núria; Slama, Rémy; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Thomsen, Cathrine; Urquiza, José M.; Vafeiadi, Marina, 1983-; Basagaña Flores, Xavier; Vrijheid, Martine (Elsevier, 2021)
    Epidemiological studies mostly focus on single environmental exposures. This study aims to systematically assess associations between a wide range of prenatal and childhood environmental exposures and cognition. The study ...

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