Browsing by Author "Lozano, Juan José"

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  • Jiménez, Natalia; Reig, Òscar; Montalbo, Ruth; Milà-Guasch, Maria; Nadal-Dieste, Lluis; Castellano, Giancarlo; Lozano, Juan José; Victoria, Iván; Font, Albert; Rodriguez-Vida, Alejo; Carles, Joan; Suárez, Cristina; Doménech, Montserrat; Sala-González, Núria; Fernández, Pedro Luís; Rodríguez-Carunchio, Leonardo; Díaz, Sherley; Prat, Aleix; Marín-Aguilera, Mercedes; Mellado, Begoña (Frontiers, 2020)
    The prostatic tumor cells plasticity is involved in resistance to hormone-therapy, allowing these cells to survive despite androgen receptor inhibition. However, its role in taxanes resistance has not been fully established. ...
  • Thomson, Timothy M.; Lozano, Juan José; Loukili, Noureddine; Carrió, Roberto; Serras Rigalt, Florenci; Cormand, Bru; Valeri, Marta; Díaz, Víctor M.; Abril Ferrando, Josep Francesc; Burset Albareda, Moisès; Merino, Jesús; Macaya, Alfons; Corominas Guiu, Montserrat; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press-CSHL Press, 2000)
    UEV proteins are enzymatically inactive variants of the E2 ubiquitin-conjugating enzymes that regulate noncanonical elongation of ubiquitin chains. In Saccharomyces cerevisiae, UEV is part of the RAD6-mediated error-free ...
  • Abulí, Anna; Castells, Antoni; Bujanda, Luis; Lozano, Juan José; Bessa Caserras, Xavier; Hernández Rodríguez, Cristina; Alvarez Urturi, Cristina; Pellisé, Maria; Esteban Jurado, Clara; Hijona, Elizabeth; Buron Pust, Andrea; Macià Guilà, Francesc Assís; Grau, Jaume; Guayta, Rafael; Castellví Bel, Sergi; Andreu García, Montserrat; PROCOLON research group (Public Library of Science, 2016)
    BACKGROUND: Common low-penetrance genetic variants have been consistently associated with colorectal cancer risk. AIM: To determine if these genetic variants are associated also with adenoma susceptibility and may improve ...
  • Mercader Bigas, Josep Maria; Lozano, Juan José; Sumoy Van Dyck, Lauro; Dierssen, Mara; Visa, Joana; Gratacós Mayora, Mònica; Estivill, Xavier, 1955- (American Physiological Society, 2008)
    The anx/anx mouse displays poor appetite and lean appearance and is considered a good model for the study of anorexia nervosa. To identify new genes involved in feeding behavior and body weight regulation we performed an ...
  • Llorens, Franc; Hummel, Manuela; Pastor Ruiz, Javier; Ferrer Salvador, Anna; Pluvinet, Raquel; Vivancos Prellezo, Ana; Castillo Andreo, Esther; Iraola Guzmán, Susana; Mosquera Miguel, Ana; González-Roca, Eva; Lozano, Juan José; Ingham, Matthew; Dohm, Juliane C.; Noguera, Marc; Kofler, Robert; Río, Jose Antonio del; Bayés, Mònica; Himmelbauer, Heinz; Sumoy Van Dyck, Lauro (BioMed Central, 2011)
    Background: Epidermal Growth Factor (EGF) is a key regulatory growth factor activating many processes relevant to normal development and disease, affecting cell proliferation and survival. Here we use a combined approach ...
  • Díaz-Gay, Marcos; Vila-Casadesús, Maria; Franch-Expósito, Sebastià; Hernández-Illán, Eva; Lozano, Juan José; Castellví Bel, Sergi (BioMed Central, 2018)
    Background: Mutational signatures have been proved as a valuable pattern in somatic genomics, mainly regarding cancer, with a potential application as a biomarker in clinical practice. Up to now, several bioinformatic ...
  • Esteban Jurado, Clara; Garre, Pilar; Vila, Maria; Lozano, Juan José; Pristoupilova, Anna; Beltrán, Sergi; Abulí, Anna; Muñoz, Jenifer; Balaguer, Francesc; Ocaña, Teresa; Castells, Antoni; Piqué, Josep M.; Carracedo, Ángel; Ruiz Ponte, Clara; Bessa Caserras, Xavier; Andreu García, Montserrat; Bujanda, Luis; Caldés, Trinidad; Castellví Bel, Sergi (Baishideng Publishing Group, 2014)
    Colorectal cancer (CRC) is one of the most frequent neoplasms and an important cause of mortality in the developed world. This cancer is caused by both genetic and environmental factors although 35% of the variation in CRC ...
  • Ortega, Guadalupe; Castellà, Cristina; Martin Cantera, Carlos; Ballvé, José L.; Díaz, Estela; Sáez, Marc; Lozano, Juan José; Rofes, Lourdes; Morera, Concepció; Barceló, Antònia; Cabezas, Carmen; Pascual, José A.; Pérez Ortuño, Raúl, 1976-; Saltó i Cerezuela, Esteve; Valverde, Araceli; Jané, Mireia; BIBE Study Group (BioMed Central, 2010)
    Background: There is evidence that exposure to passive smoking in general, and in babies in particular, is an important cause of morbimortality. Passive smoking is related to an increased risk of pediatric diseases such ...
  • Pablo Fontecha, Verónica; Hernández-Illán, Eva; Reparaz, Andrea; Asensio Juan, Elena; Morata, Jordi; Tonda, Raúl; Lahoz, Sara; Parra, Carolina; Lozano, Juan José; García-Heredia, Anabel; Martínez-Roca, Alejandro; Beltran, Sergi; Balaguer, Francesc; Jover, Rodrigo; Castells, Antoni; Trullàs, Ramón; Podlesniy, Petar; Camps-Puchadas, Jordi (Nature Research, 2023)
    Somatic single-nucleotide variants (SNVs) occur every time a cell divides, appearing even in healthy tissues at low frequencies. These mutations may accumulate as neutral variants during aging, or eventually, promote the ...
  • Sánchez-Tilló, Ester; Pedrosa, Leire; Vila, Ingrid; Chen, Yongxu; Gyorffy, Balázs; Sánchez-Moral, Lidia; Siles, Laura; Lozano, Juan José; Esteve-Codina, Anna; Darling, Douglas S.; Cuatrecasas, Miriam; Castells, Antoni; Maurel, Joan; Postigo, Antonio (American Society for Clinical Investigation, 2023)
    Despite being in the same pathway, mutations of KRAS and BRAF in colorectal carcinomas (CRCs) determine distinct progression courses. ZEB1 induces an epithelial-to-mesenchymal transition (EMT) and is associated with worse ...

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