Browsing by Author "Lluís Ganella, Carla, 1984-"

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  • Musameh, Muntaser D.; Wang, William Y. S.; Nelson, Christopher P.; Lluís Ganella, Carla, 1984-; Debiec, Radoslaw; Subirana Cachinero, Isaac; Elosua Llanos, Roberto; Balmforth, Anthony J.; Ball, Stephen G.; Hall, Alistair S.; Kathiresan, Sekar; Thompson, John R.; Lucas, Gavin, 1977-; Samani, Nilesh J.; Tomaszewski, Maciej (Public Library of Science, 2015)
    OBJECTIVE: Only a small fraction of coronary artery disease (CAD) heritability has been explained by common variants identified to date. Interactions between genes of importance to cardiovascular regulation may account for ...
  • Elosua Llanos, Roberto; Lluís Ganella, Carla, 1984-; Subirana Cachinero, Isaac; Havulinna, Aki; Läll, Kristi; Lucas, Gavin, 1977-; Sayols, Sergi; Pietilä, Arto; Alver, Maris; Cabrera de León, Antonio; Sentí Clapés, Mariano; Siscovick, David; Mellander, Olle; Fischer, Krista; Salomaa, Veikko; Marrugat de la Iglesia, Jaume (Lippincott Williams & Wilkins, 2016)
    BACKGROUND: Cardiovascular risk factors tend to aggregate. The biological and predictive value of this aggregation is questioned and genetics could shed light on this debate. Our aims were to reappraise the impact of risk ...
  • Sayols Baixeras, Sergi, 1988-; Hernáez, Álvaro; Subirana Cachinero, Isaac; Lluís Ganella, Carla, 1984-; Muñoz Aguayo, Daniel; Fitó Colomer, Montserrat; Marrugat de la Iglesia, Jaume; Elosua Llanos, Roberto (American Hearth Association, 2017)
    Objective: The function of high-density lipoproteins (HDLs) may better reflect their atheroprotective role, compared with HDL-cholesterol levels. The association between DNA methylation and HDL function has not yet been ...
  • Sayols Baixeras, Sergi (Universitat Pompeu Fabra, 2019-02-25)
    La malaltia cardiovascular, que és primera causa de mortalitat al món, com a fenotip complex depèn tant dels factors ambientals com dels genètics. Les variants genètiques comunes expliquen un 15-20% de l’heretabilitat ...
  • Lluís Ganella, Carla, 1984- (Universitat Pompeu Fabra, 2012-10-03)
    The main expansion of the discovery of genetic variants associated with complex diseases has occurred during the last decade. This expansion has been accompanied, and in some sense motivated, by the desire to use this ...
  • Lucas, Gavin, 1977-; Lluís Ganella, Carla, 1984-; Subirana Cachinero, Isaac; Musameh, Muntaser D.; González Ruiz, Juan Ramón; Nelson, Christopher P.; Sentí Clapés, Mariano; Myocardial Infarction Genetics; Wellcome Trust Case Control Constortium; Schwartz, Stephen M; Siscovick, David; O'Donnell, Christopher J; Melander, Olle; Salomaa, Veikko; Purcell, Shaun; Altshuler, David; Samani, Nilesh J.; Kathiresan, Sekar; Elosua Llanos, Roberto (Public Library of Science (PLoS), 2012)
    The genetic loci that have been found by genome-wide association studies to modulate risk of coronary heart disease explain only a fraction of its total variance, and gene-gene interactions have been proposed as a potential ...
  • Sayols, Sergi; Subirana Cachinero, Isaac; Lluís Ganella, Carla, 1984-; Civeira, Fernando; Roquer, Jaume; Do, AN; Absher, Devin; Cenarro, A.; Muñoz, Daniel; Soriano Tarraga, Carolina; Jiménez Conde, Jordi; Ordovás, José M.; Sentí Clapés, Mariano; Aslibekyan, Stella W.; Marrugat de la Iglesia, Jaume; Arnett, Donna K.; Elosua Llanos, Roberto (Oxford University Press, 2016)
    Lipid traits (total, low-densityand high-density lipoproteincholesterol, and triglycerides) are risk factors for cardiovascular disease. DNA methylation is an inherited but also modifiable epigenetic mark ...
  • Sayols, Sergi; Lluís Ganella, Carla, 1984-; Subirana Cachinero, Isaac; Salas, Lucas A.; Vilahur Chiaraviglio, Nadia, 1982-; Corella, Dolores; Muñoz, Daniel; Segura, Antoni, 1952-; Jiménez Conde, Jordi; Moran, Sebastian; Soriano Tarraga, Carolina; Roquer, Jaume; Lopez-Farré, Antonio; Marrugat de la Iglesia, Jaume; Fitó Colomer, Montserrat; Elosua Llanos, Roberto (Taylor & Francis, 2015)
    Smoking increases the risk of many diseases and could act through changes in DNA methylation patterns. The aims of this study were to determine the association between smoking and DNA methylation throughout the genome at ...
  • Iribarren, Carlos; Lu, Meng; Jorgenson, Eric; Martínez, Manuel; Lluís Ganella, Carla, 1984-; Subirana Cachinero, Isaac; Salas, Eduardo; Elosua Llanos, Roberto (Nature Research, 2018)
    We examined the clinical utility of two multi-locus genetic risk scores (GRSs) previously validated in Europeans among persons of African (AFR; n = 2,089), Latino (LAT; n = 4,349) and East-Asian (EA; n = 4,804) ancestry. ...

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