Browsing by Author "Lloreta Trull, Josep, 1958-"

Sort by: Order: Results:

  • Agell, Laia; Hernández, Silvia; Nonell Mazelón, Lara; Lorenzo Perez, Marta; Puigdecanet Riubugent, Eulàlia; Muga, Silvia de; Juanpere, Nuria; Bermudo, Raquel; Fernández, Pedro L.; Lorente Garin, José Antonio; Serrano Figueras, Sergi; Lloreta Trull, Josep, 1958- (Elsevier, 2012)
    The main challenge for clinical management of prostate cancer is to distinguish tumors that will progress faster and will show a higher tendency to recur from the more indolent ones. We have compared expression profiles ...
  • Rothman, Nathaniel; Real, Francisco X.; Serra, Consol; Lloreta Trull, Josep, 1958-; Chanock, Stephen J. (Nature Research, 2010)
    We conducted a multi-stage, genome-wide association study of bladder cancer with a primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of European descent from five studies followed by a ...
  • Balbás Martínez, Cristina; Rodríguez Pinilla, María; Casanova, Ariel; Domínguez, Orlando; Pisano, David G.; Gómez López, Gonzalo; Lloreta Trull, Josep, 1958-; Lorente Garin, José Antonio; Malats i Riera, Núria; Real, Francisco X. (Public Library of Science (PLoS), 2013)
    Urothelial bladder cancer (UBC) is heterogeneous at the clinical, pathological, genetic, and epigenetic levels. Exome sequencing has identified ARID1A as a novel tumor suppressor gene coding for a chromatin remodeling ...
  • del Rey, Javier; Prat, Esther; Ponsa, Immaculada; Lloreta Trull, Josep, 1958-; Gelabert, Antoni; Algaba, Ferran; Camps, Jordi; Miró, Rosa (BioMed Central, 2010)
    Background: Aneuploidy, centrosome abnormalities and gene amplification are hallmarks of chromosome instability (CIN) in cancer. Yet there are no studies of the in vivo behavior of these phenomena within the same bladder ...
  • Núñez Ollé, Marc, 1984-; Jung, Carole; Terré, Berta; Balsiger, Norman A.; Plata, Cristina; Roset i Huguet, Ramon; Pardo Pastor, Carlos; Garrido, Marta; Rojas, Santiago; Alameda Quitllet, Francisco; Lloreta Trull, Josep, 1958-; Martín Caballero, Juan; Flores, Juana M.; Stracker, Travis; Valverde, M. A. (Miguel Ángel), 1963-; Muñoz López, Francisco José, 1964-; Gil Gómez, Gabriel (Impact Journals, 2017)
    Cyclin O (encoded by CCNO) is a member of the cyclin family with regulatory functions in ciliogenesis and apoptosis. Homozygous CCNO mutations have been identified in human patients with Reduced Generation of Multiple ...
  • Alejo, María; Alemany, Laia; Clavero, Omar; Quirós, Beatriz; Vighi, Susana Graciela; Seoud, Muhieddine; Cheng-Yang, Chou; Garland, Suzanne Marie; Juanpere, Nuria; Lloreta Trull, Josep, 1958-; Tous, Sara; Klaustermeier, Jo Ellen; Quint, Wim G.V.; Bosch, Francesc Xavier; Sanjosé Llongueras, Silvia de; Lloveras Rubio, Belen; RIS Human papillomavirus (HPV) TT study group (Elsevier, 2018)
    AIMS: Neuroendocrine tumors (NET) of the cervix are rare tumors with a very aggressive course. The human papillomavirus (HPV) has been linked to its etiology. The objective of this study is to describe HPV prevalence and ...
  • Czachorowski, Maciej J; Amaral, André F.S.; Montes-Moreno, Santiago; Lloreta Trull, Josep, 1958-; Carrato, Alfredo; Tardón, Adonina; Morente, Manuel M; Kogevinas, Manolis; Real, Francisco X.; Malats i Riera, Núria (Public Library of Science (PLoS), 2012)
    Aberrant overexpression of cyclooxygenase-2 (COX2) is observed in urothelial carcinoma of the bladder (UCB). Studies evaluating COX2 as a prognostic marker in UCB report contradictory results. We determined the prognostic ...
  • Riera Oliva, Marta; Márquez, Eva; Clotet, Sergi; Gimeno, Javier; Roca-Ho, Heleia; Lloreta Trull, Josep, 1958-; Juanpere, Nuria; Batlle, Daniel; Pascual Santos, Julio; Soler, María José (Public Library of Science (PLoS), 2014)
    We studied the non-obese diabetic (NOD) mice model because it develops autoimmune diabetes that resembles human type 1 diabetes. In diabetic mice, urinary albumin excretion (UAE) was ten-fold increased at an “early stage” ...
  • Hernández Llodrà, Sílvia; Juanpere, Nuria; Muga, Silvia de; Lorenzo Perez, Marta; Gil Ortega, Joan; Font Tello, Alba 1990-; Agell, Laia; Albero-González, Raquel; Segalés, Laura; Merino, José; Serrano, Laia; Fumadó Ciutat, Lluis; Cecchini Rosell, Lluís; Lloreta Trull, Josep, 1958- (Impact Journals, 2017)
    TMPRSS2 and SLC45A3 rearrangements may coexist in the same tumor. ERG rearrangements and PTEN loss are concomitant events in prostate cancer (PrCa), and can cooperate in progression. We have reported that mRNA expression ...
  • Lloreta Trull, Josep, 1958-; Font-Tello, Alba; Juanpere, Nuria; Frances, Albert; Lorenzo Perez, Marta; Nonell Mazelón, Lara; Muga, Silvia de; Vázquez‐de las Heras, Ivonne; Cecchini Rosell, Lluís; Hernández, Silvia (Elsevier, 2017)
    Nuclear FOXOs mediate cell cycle arrest and promote apoptosis. FOXOs and p53 could have similar effects as tumor suppressor genes. In spite of extensive literature, little is known about the role of FOXO1 and its relationship ...
  • Pineda, Silvia; Milne, Roger L.; Calle, M. Luz; Rothman, Nathaniel; López De Maturana, Evangelina; Herranz, Jesús; Kogevinas, Manolis; Chanock, Stephen J.; Tardón, Adonina; Márquez, Mirari; Guey, Lin T.; García Closas, Montserrat; Lloreta Trull, Josep, 1958-; Baum, Erin; González Neira, Anna; Carrato, Alfredo; Navarro i Cuartiellas, Arcadi, 1969-; Silverman, Debra T.; Real, Francisco X.; Malats i Riera, Núria (Public Library of Science (PLoS), 2014)
    Introduction: Germline variants in TP63 have been consistently associated with several tumors, including bladder cancer, indicating the importance of TP53 pathway in cancer genetic susceptibility. However, variants in other ...
  • Menashe, Idan; Real, Francisco X.; Kogevinas, Manolis; Serra, Consol; Lloreta Trull, Josep, 1958-; Rothman, Nathaniel (Public Library of Science (PLoS), 2012)
    Pathway analysis of genome-wide association studies (GWAS) offer a unique opportunity to collectively evaluate genetic variants with effects that are too small to be detected individually. We applied a pathway analysis to ...
  • Sintes, Jordi; Serrano Figueras, Sergi; Lloreta Trull, Josep, 1958-; Cerutti, Andrea, 1965- (Nature Publishing Group, 2017)
    Mechanistic target of rapamycin (mTOR) enhances immunity in addition to orchestrating metabolism. Here we show that mTOR coordinates immunometabolic reconfiguration of marginal zone (MZ) B cells, a pre-activated lymphocyte ...
  • Rovira Clusellas, Meritxell; Delaspre, Fabien; Massumi, Mohammad; Serra Pascual, Selma A., 1981-; Valverde, M. A. (Miguel Ángel), 1963-; Lloreta Trull, Josep, 1958-; Dufresne, Marlène; Payré, Bruno; Konieczny, Stephen F.; Savatier, Pierre; Real, Francisco X.; Skoudy, Anouchka (Elsevier, 2008)
    Background & Aims: Acinar cells constitute 90% of the pancreas epithelium, are polarized, and secrete digestive enzymes. These cells play a crucial role in pancreatitis and pancreatic cancer. However, there are limited ...
  • Guitart, Maria; Lloreta Trull, Josep, 1958-; Mañas-García, Laura; Barreiro Portela, Esther (Wiley, 2018)
    Reduced muscle activity leads to muscle atrophy and function loss in patients and animal models. Satellite cells (SCs) are postnatal muscle stem cells that play a pivotal role in skeletal muscle regeneration following ...
  • García Closas, Montserrat; Malats i Riera, Núria; Kogevinas, Manolis; Serra, Consol; Lloreta Trull, Josep, 1958-; Castaño Vinyals, Gemma; Torà, Montserrat; Fernández-Avilés, Francisco; Real, Francisco X.; Rothman, Nathaniel (Elsevier, 2005)
    BACKGROUND: Many reported associations between common genetic polymorphisms and complex diseases have not been confirmed in subsequent studies. An exception could be the association between NAT2 slow acetylation, GSTM1 ...
  • García Closas, Montserrat; Malats i Riera, Núria; Kogevinas, Manolis; Serra, Consol; Lloreta Trull, Josep, 1958-; Real, Francisco X.; Rothman, Nathaniel (Elsevier, 2005)
    Background: Many reported associations between common genetic polymorphisms and complex diseases have not been confirmed in subsequent studies. An exception could be the association between NAT2 slow acetylation, GSTM1 ...
  • López De Maturana, Evangelina; Picornell, Antoni; Masson-Lecomte, Alexandra; Kogevinas, Manolis; Márquez, Mirari; Carrato, Alfredo; Tardón, Adonina; Lloreta Trull, Josep, 1958-; García Closas, Montserrat; Silverman, Debra T.; Rothman, Nathaniel; Chanock, Stephen J.; Real, Francisco X.; Goddard, M. E.; Malats i Riera, Núria; SBC/EPICURO Study Investigators (BioMed Central, 2016)
    BACKGROUND: We adapted Bayesian statistical learning strategies to the prognosis field to investigate if genome-wide common SNP improve the prediction ability of clinico-pathological prognosticators and applied it to ...