Visualitza per autoria "Lau, Chung-Ho E."

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  • Assessment of metabolic phenotypic variability in children’s urine using 1H NMR spectroscopy
    Maitre, Léa; Lau, Chung-Ho E.; Vizcaino, Esther; Robinson, Oliver; Casas Sanahuja, Maribel; Siskos, Alexandros P.; Want, Elizabeth J.; Athersuch, Toby J.; Slama, Rémy; Vrijheid, Martine; Keun, Hector C.; Coen, Muireann (Nature Research, 2017)
    The application of metabolic phenotyping in clinical and epidemiological studies is limited by a poor understanding of inter-individual, intra-individual and temporal variability in metabolic phenotypes. Using 1H NMR ...
  • Associations of four biological age markers with child development: A multi-omic analysis in the European HELIX cohort
    Robinson, Oliver; Lau, Chung-Ho E.; Joo, Sungyeon; Andrušaitytė, Sandra; Borràs, Eva; Prado Bert, Paula de; Chatzi, Lida Vaia; Keun, Hector C.; Gražulevičienė, Regina; Gutzkow, Kristine B.; Maitre, Léa; Martens, Dries S.; Sabidó Aguadé, Eduard, 1981-; Siroux, Valérie; Urquiza, José M.; Vafeiadi, Marina, 1983-; Wright, John; Nawrot, Tim S.; Bustamante Pineda, Mariona; Vrijheid, Martine (eLife, 2023)
    Background: While biological age in adults is often understood as representing general health and resilience, the conceptual interpretation of accelerated biological age in children and its relationship to development ...
  • Childhood exposure to non-persistent endocrine disrupting chemicals and multi-omic profiles: a panel study
    Fabbri, Lorenzo; Garlantézec, Ronan; Audouze, Karine; Bustamante Pineda, Mariona; Carracedo, Ángel; Chatzi, Leda; González, Juan Ramón; Gražulevičienė, Regina; Keun, Hector C.; Lau, Chung-Ho E.; Sabidó, Eduard; Siskos, Alexandros P.; Slama, Rémy; Thomsen, Cathrine; Wright, John; Yuan, Wen Lun; Casas, Maribel; Vrijheid, Martine; Maitre, Léa (Elsevier, 2023)
    Individuals are exposed to environmental pollutants with endocrine disrupting activity (endocrine disruptors, EDCs) and the early stages of life are particularly susceptible to these exposures. Previous studies have focused ...
  • Determinants of the urinary and serum metabolome in children from six European populations
    Lau, Chung-Ho E.; Maitre, Léa; Urquiza, José M.; Casas Sanahuja, Maribel; Vrijheid, Martine; Coen, Muireann (BioMed Central, 2018)
    Background: Environment and diet in early life can affect development and health throughout the life course. Metabolic phenotyping of urine and serum represents a complementary systems-wide approach to elucidate ...
  • Urinary metabolite quantitative trait loci in children and their interaction with dietary factors
    Calvo Serra, Beatriz; Maitre, Léa; Lau, Chung-Ho E.; Siskos, Alexandros P.; Gützkow, Kristine B.; Andrušaitytė, Sandra; Casas Sanahuja, Maribel; Cadiou, Solène; Chatzi, Leda; González, Juan Ramón; Gražulevičienė, Regina; McEachan, Rosemary R.C.; Slama, Rémy; Vafeiadi, Marina, 1983-; Wright, John; Coen, Muireann; Vrijheid, Martine; Keun, Hector C.; Escaramís, Geòrgia; Bustamante Pineda, Mariona (Oxford University Press, 2021)
    Human metabolism is influenced by genetic and environmental factors. Previous studies have identified over 23 loci associated with more than 26 urine metabolites levels in adults, which are known as urinary metabolite ...

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