Browsing by Author "Latorre Doménech, Pablo, 1993-"

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  • Data-driven identification of inherent features of eukaryotic stress-responsive genes
    Latorre Doménech, Pablo, 1993-; Böttcher, René; Nadal Ribelles, Mariona, 1984-; Li, Constance H.; Solé, Carme; Martínez Cebrián, Gerard, 1992-; Boutros, Paul C.; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (Oxford University Press, 2022)
    Living organisms are continuously challenged by changes in their environment that can propagate to stresses at the cellular level, such as rapid changes in osmolarity or oxygen tension. To survive these sudden changes, ...
  • Decoding the nature of the transcriptional response to stress
    Latorre Doménech, Pablo, 1993- (2021-06-15)
    Virtually all living organisms are challenged by changes in their environment, such as sudden increases in osmolarity. To cope with these stresses, cells have developed stress responses that tune every aspect of cell ...
  • LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions
    Serra, Selma A.; Stojakovic, Predrag; Amat, Ramon; Rubio Moscardó, Fanny; Latorre Doménech, Pablo, 1993-; Seisenbacher, Gerhard; Canadell, David; Böttcher, René; Aregger, Michael; Moffat, Jason; Nadal Clanchet, Eulàlia de; Valverde, M. A. (Miguel Ángel), 1963-; Posas Garriga, Francesc (National Academy of Sciences, 2021)
    Regulation of cell volume is essential for tissue homeostasis and cell viability. In response to hypertonic stress, cells need rapid electrolyte influx to compensate water loss and to prevent cell death in a process known ...
  • Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program
    Jiménez, Carlos; Antonelli, Roberta; Nadal-Ribelles, Mariona; Devis-Jauregui, Laura; Latorre Doménech, Pablo, 1993-; Solé, Carme; Masanas, Marc; Molero-Valenzuela, Adrià; Soriano, Aroa; Sánchez de Toledo, Josep; Llobet-Navas, David; Roma, Josep; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de; Gallego, Soledad; Moreno, Lucas; Segura, Miguel F. (BioMed Central, 2022)
    Background: Epigenetic programming during development is essential for determining cell lineages, and alterations in this programming contribute to the initiation of embryonal tumour development. In neuroblastoma, neural ...