Browsing by Author "Lao Grueso, Oscar, 1976-"

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  • López De Maturana, Evangelina; Rodríguez, Juan Antonio; Lao Grueso, Oscar, 1976-; Iglesias Coma, Mar; Cecchini Rosell, Lluís; Ilzarbe Sánchez, Lucas; Real, Francisco X.; Malats i Riera, Núria (BioMed Central, 2021)
    Background: Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% ...
  • Mendizábal Eceizabarrena, Isabel, 1981-; Marigorta, Urko M.; Lao Grueso, Oscar, 1976-; Comas, David, 1969- (Springer, 2012)
    African Pygmies are hunter-gatherer populations from the equatorial rainforest that present the lowest height averages among humans. The biological basis and the putative adaptive role of the short stature of Pygmy populations ...
  • Maceda Porto, Iago, 1986-; Lao Grueso, Oscar, 1976- (MDPI, 2021)
    The 1000 Genomes Project (1000G) is one of the most popular whole genome sequencing datasets used in different genomics fields and has boosting our knowledge in medical and population genomics, among other fields. Recent ...
  • Mondal, Mayukh, 1989-; Bertranpetit, Jaume, 1952-; Lao Grueso, Oscar, 1976- (Nature Research, 2019)
    Since anatomically modern humans dispersed Out of Africa, the evolutionary history of Eurasian populations has been marked by introgressions from presently extinct hominins. Some of these introgressions have been identified ...
  • Moreno-Ruiz, Nerea; Genomics England Research Consortium; Lao Grueso, Oscar, 1976-; Aróstegui Gorospe, Juan Ignacio; Laayouni, Hafid, 1968-; Casals López, Ferran (Nature Research, 2022)
    An important fraction of patients with rare disorders remains with no clear genetic diagnostic, even after whole-exome or whole-genome sequencing, posing a difficulty in giving adequate treatment and genetic counseling. ...
  • de Manuel, Marc; Kuhlwilm, Martin; Sousa, Victor C.; Prado Martínez, Javier, 1987-; Hernández Rodríguez, Jéssica, 1983-; Dupanloup, Isabelle; Lao Grueso, Oscar, 1976-; Heredia Genestar, José María, 1985-; Kuderna, Lukas, 1989-; Casals López, Ferran; Angedakin, Samuel; Arandjelovic, Mimi; Boesch, Christophe; Kühl, Hjalmar S.; Vigilant, Linda; Navarro i Cuartiellas, Arcadi, 1969-; Excoffier, Laurent; Marquès i Bonet, Tomàs, 1975- (American Association for the Advancement of Science (AAAS), 2016)
    Our closest living relatives, chimpanzees and bonobos, have a complex demographic history. We analyzed the high-coverage whole genomes of 75 wild-born chimpanzees and bonobos from 10 countries in Africa. We found that ...
  • Jablonszky, Mónika; Canal, David; Hegyi, Gergely; Herényi, Márton; Laczi, Miklós; Lao Grueso, Oscar, 1976-; Markó, Gábor; Nagy, Gergely; Rosivall, Balázs; Szász, Eszter; Török, János; Zsebők, Sándor; Garamszegi, László Zsolt (Frontiers, 2022)
    Heritable genetic variation is a prerequisite for adaptive evolution; however, our knowledge about the heritability of plastic traits, such as behaviors, is scarce, especially in wild populations. In this study, we ...
  • Dolgova, Olga; Lao Grueso, Oscar, 1976- (MDPI, 2018)
    The demographic history of anatomically modern humans (AMH) involves multiple migration events, population extinctions and genetic adaptations. As genome-wide data from complete genome sequencing becomes increasingly ...
  • Fernàndez-Castillo, Noèlia; Cabana-Domínguez, Judit; Kappel, Djenifer B.; Torrico, Bàrbara; Weber, Keike; Lesch, Klaus-Peter; Lao Grueso, Oscar, 1976-; Reif, Andreas; Cormand, Bru (MDPI, 2021)
    Attention-deficit hyperactivity disorder (ADHD) is a complex neurodevelopmental disorder characterized by hyperactivity, impulsivity, and/or inattention, which are symptoms also observed in many rare genetic disorders. We ...
  • Maceda Porto, Iago, 1986-; Martín Álvarez, Miguel; Athanasiadis, Georgios; Tonda, Raúl; Camps-Puchadas, Jordi; Beltran, Sergi; Camps, Agustí; Fàbrega, Jordi; Felisart, Josefina; Grané, Joan; Remón, José Luis; Serra, Jordi; Moral, Pedro; Lao Grueso, Oscar, 1976- (Springer Nature, 2021)
    The area of the Spanish Pyrenees is particularly interesting for studying the demographic dynamics of European rural areas given its orography, the main traditional rural condition of its population and the reported higher ...
  • Esteller Cucala, Paula; Maceda Porto, Iago, 1986-; Børglum, Anders D.; Demontis, Ditte; Faraone, Stephen V.; Cormand, Bru; Lao Grueso, Oscar, 1976- (Nature Research, 2020)
    Attention-deficit/hyperactivity disorder (ADHD) is an impairing neurodevelopmental condition highly prevalent in current populations. Several hypotheses have been proposed to explain this paradox, mainly in the context of ...
  • González Neira, Anna; Calafell i Majó, Francesc; Navarro i Cuartiellas, Arcadi, 1969-; Lao Grueso, Oscar, 1976-; Cann, Howard M.; Comas, David, 1969-; Bertranpetit, Jaume, 1952- (BioMed Central, 2004)
    Recent studies of haplotype diversity in a number of genomic regions have suggested that long stretches of DNA are preserved in the same chromosome, with little evidence of recombination events. The knowledge of the extent ...
  • Dolgova, Olga; Lao Grueso, Oscar, 1976- (MDPI, 2018)
    Evolutionary medicine applies the principles of evolutionary biology to understand why we get sick rather than how, and it has undergone an exponential growth since the early 1990s [...].
  • Marigorta, Urko M.; Lao Grueso, Oscar, 1976-; Casals López, Ferran; Calafell i Majó, Francesc; Morcillo Suárez, Carlos, 1969-; Faria, Rui; Bosch Fusté, Elena; Serra, François; Bertranpetit, Jaume, 1952-; Dopazo, Hernán; Navarro i Cuartiellas, Arcadi, 1969- (BioMed Central, 2011)
    Background: Searching for associations between genetic variants and complex diseases has been a very active area of research for over two decades. More than 51,000 potential associations have been studied and published, a ...
  • Vives, Sergi; Gilbert, M Thomas; Arenas, Conxita; Gigli, Elena, 1978-; Lao Grueso, Oscar, 1976-; Lalueza Fox, Carles, 1965- (BioMed Central, 2008)
    Background: We have analysed the distribution of post mortem DNA damage derived miscoding lesions from the datasets of seven published Neandertal specimens that have extensive cloned sequence coverage over the mitochondrial ...
  • Altena, Eveline; Smeding, Risha; van der Gaag, Kristiaan J.; Larmuseau, Maarten H. D.; Decorte, Ronny; Lao Grueso, Oscar, 1976-; Kayser, Manfred; Kraaijenbrink, Thirsa; de Knijff, Peter (Nature Research, 2020)
    Previous studies indicated existing, albeit limited, genetic-geographic population substructure in the Dutch population based on genome-wide data and a lack of this for mitochondrial SNP based data. Despite the aforementioned ...
  • Clemente, Florian; Dolgova, Olga; Lao Grueso, Oscar, 1976-; Papageorgopoulou, Christina (Elsevier, 2021)
    The Cycladic, the Minoan, and the Helladic (Mycenaean) cultures define the Bronze Age (BA) of Greece. Urbanism, complex social structures, craft and agricultural specialization, and the earliest forms of writing characterize ...
  • Fibla, Joan; Maceda Porto, Iago, 1986-; Laplana, Marina; Guerrero, Montserrat; Martín Álvarez, Miguel; Burgueño, Jesús; Camps, Agustí; Fàbrega, Jordi; Felisart, Josefina; Grané, Joan; Remón, José Luis; Serra, Jordi; Moral, Pedro; Lao Grueso, Oscar, 1976- (Frontiers, 2023)
    The genetic variation of the European population at a macro-geographic scale follows genetic gradients which reflect main migration events. However, less is known about factors affecting mating patterns at a micro-geographic ...
  • Lorente-Galdós, Belén, 1981-; Lao Grueso, Oscar, 1976-; Serra Vidal, Gerard, 1989-; Santpere Baró, Gabriel, 1981-; Kuderna, Lukas, 1989-; Arauna, Lara R; Fadhlaoui-Zid, Karima; Pimenoff, Ville N.; Soodyall, Himla; Zalloua, Pierre A.; Marquès i Bonet, Tomàs, 1975-; Comas, David, 1969- (BioMed Central, 2019)
    Background: Population demography and gene flow among African groups, as well as the putative archaic introgression of ancient hominins, have been poorly explored at the genome level. Results: Here, we examine 15 African ...

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