Browsing by Author "Langohr, Klaus"

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  • Pastor, Antonio; Fernández Aranda, Fernando; Fitó Colomer, Montserrat; Jiménez Murcia, Susana; Botella, Cristina; Fernández Real, Jose M.; Frühbeck, Gema; Tinahones Madueño, Francisco José; Fagundo, Ana B.; Rodríguez Rodríguez, Juan Francisco; Agüera, Zaida; Langohr, Klaus; Casanueva, Felipe F.; Torre Fornell, Rafael de la (Public Library of Science , 2016)
    The endocannabinoid (eCB) system can promote food intake by increasing odor detection in mice. The eCB system is over-active in human obesity. Our aim is to measure circulating eCB concentrations and olfactory capacity in ...
  • Sola Llopis, Susana de; Torre Fornell, Rafael de la; Sánchez Benavides, Gonzalo; Benejam, Bessy; Cuenca Royo, Aida Ma, 1981-; Del Hoyo Soriano, Laura; Rodríguez, Joan; Catuara Solarz, Silvina, 1986-; Sánchez Gutiérrez, Judit; Dueñas-Espín, Iván, 1979-; Hernández, Gimena; Peña-Casanova, J. (Jordi); Langohr, Klaus; Videla, Sebastià; Blehaut, Henry; Farré Albaladejo, Magí; Dierssen, Mara; TESDAD Study Group (Frontiers, 2015)
    The recent prospect of pharmaceutical interventions for cognitive impairment of Down syndrome (DS) has boosted a number of clinical trials in this population. However, running the trials has raised some methodological ...
  • Boronat Rigol, Anna; Mateus Rodriguez, Julian Andrés; Soldevila-Domenech, Natalia; Guerra, Mercè; Rodríguez-Morató, Jose, 1987-; Varon, Carlota; Muñoz Aguayo, Daniel; Barbosa, Francina; Morales, Juan Carlos; Gaedigk, Andreas; Langohr, Klaus; Covas Planells, Maria Isabel; Pérez Mañá, Clara; Fitó Colomer, Montserrat; Tyndale, Rachel F.; Torre Fornell, Rafael de la (Elsevier, 2019)
    Introduction: The simple phenol hydroxytyrosol (OHTyr) has been associated with the beneficial health effects of extra virgin olive oil. Pre-clinical studies have identified Tyr hydroxylation, mediated by cytochrome P450 ...
  • Pardo Lozano, Ricardo; Farré Albaladejo, Magí; Yubero Lahoz, Samanta, 1985-; O'Mathuna, Brian; Torrens, Marta; Mustata, Cristina; Pérez Mañá, Clara; Langohr, Klaus; Cuyàs, Elisabet; Carbó Banús, Marcel·lí; Torre Fornell, Rafael de la (Public Library of Science (PLoS), 2012)
    The synthetic psychostimulant MDMA (±3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). ...
  • Catuara Solarz, Silvina, 1986-; Espinosa-Carrasco, José; Erb, Ionas; Langohr, Klaus; Gonzalez, Juan Ramon; Notredame, Cedric; Dierssen, Mara (Society for Neuroscience, 2016)
    Intellectual disability in Down syndrome (DS) is accompanied by altered neuro-architecture, deficient synaptic plasticity, and excitation-inhibition imbalance in critical brain regions for learning and memory. Recently, ...
  • Boronat Rigol, Anna, 1990-; Mateus Rodriguez, Julian Andrés; Soldevila-Domenech, Natalia; Guerra Albà, Mercè; Rodríguez-Morató, Jose, 1987-; Varon, Carlota; Muñoz, Daniel; Barbosa, Francina; Morales, Juan Carlos; Gaedigk, Andreas; Langohr, Klaus; Covas Planells, Maria Isabel; Pérez Mañá, Clara; Fitó Colomer, Montserrat; Tyndale, Rachel F.; Torre Fornell, Rafael de la (Elsevier, 2019)
    Here we present new and original data on the endogenous conversion of tyrosol (Tyr) into hydroxytyrosol (OHTyr) in humans and its effects on the cardiovascular system. A randomized, crossover, controlled clinical trial was ...
  • Udina, M. ; Navinés, Ricard; Egmond, E.  ; Oriolo, Giovanni; Langohr, Klaus; Gimenez, Dolors; Valdés, M. ; Gómez-Gil, E. ; Grande, Iria; Gratacós Mayora, Mònica; Kapczinski, F.  ; Artigas, Francesc; Vieta, Eduard; Solà, Rosa; Martín Santos, Rocío (Oxford University Press, 2016)
    BACKGROUND: The role of inflammation in mood disorders has received increased attention. There is substantial evidence that cytokine therapies, such as interferon alpha (IFN-alpha), can induce depressive symptoms. Indeed, ...
  • Cuyàs, Elisabet; Verdejo García, Antonio; Fagundo, Ana B.; Khymenets, Olha, 1974-; Rodríguez, Joan; Cuenca Royo, Aida Ma, 1981-; De Sola Llopis, Susana; Langohr, Klaus; Peña-Casanova, J. (Jordi); Torrens, Marta; Martín Santos, Rocío; Farré Albaladejo, Magí; Torre Fornell, Rafael de la (Public Library of Science (PLoS), 2011)
    This study is aimed to clarify the association between MDMA cumulative use and cognitive dysfunction, and the potential role of candidate genetic polymorphisms in explaining individual differences in the cognitive effects ...
  • Soldevila-Domenech, Natalia; Boronat Rigol, Anna; Langohr, Klaus; Torre Fornell, Rafael de la (Frontiers, 2019)
    Longer life expectancy has led to an increase in the prevalence of age-related cognitive decline and dementia worldwide. Due to the current lack of effective treatment for these conditions, preventive strategies represent ...
  • Pérez Mañá, Clara; Farré Albaladejo, Magí; Pastor, Antonio; Fonseca Casals, Francina, 1972-; Torrens, Marta; Menoyo Colomer, Esther; Pujadas Bastardes, Mitona; Frias, Silvia; Langohr, Klaus; Torre Fornell, Rafael de la (Oxford University Press, 2017)
    AIMS: Ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) are non-oxidative metabolites of alcohol that can be detected in conventional and non-conventional biological matrices for longer periods than alcohol. The ...
  • Goday Arno, Alberto; Farré Albaladejo, Magí; Rodríguez-Morató, Jose, 1987-; Ramón Moros, José Manuel; Pérez Mañá, Clara; Papaseit Fontanet, Esther; Civit, Ester; Langohr, Klaus; Carbó Banús, Marcel·lí; Benaiges Foix, David; Castañer, Olga; Flores-Le-Roux, Juana Antonia; Pera Roman, Manuel Ramón; Grande Posa, Luís; Torre Fornell, Rafael de la (Springer, 2017)
    PURPOSE: The purpose of the study was to study the impact of the two most common bariatric surgery techniques on paracetamol pharmacokinetics (a marker of gastric emptying) and caffeine metabolism (a marker of liver ...
  • Catuara Solarz, Silvina, 1986-; Espinosa-Carrasco, José; Erb, Ionas; Langohr, Klaus; Notredame, Cedric; González Ruiz, Juan Ramón; Dierssen, Mara (Frontiers, 2015)
    Down syndrome (DS) individuals present increased risk for Alzheimer's disease (AD) neuropathology and AD-type dementia. Here, we investigated the use of green tea extracts containing (-)-epigallocatechin-3-gallate (EGCG), ...
  • Chacón Cabrera, Alba, 1988-; Mateu-Jimenez, Mercè; Langohr, Klaus; Fermoselle Pérez, Clara, 1985-; García-Arumí, Elena; Andreu, Antoni; Yelamos López, Jose; Barreiro Portela, Esther (Wiley, 2017)
    Strategies to treat cachexia are still at its infancy. Enhanced muscle protein breakdown and ubiquitin-proteasome system are common features of cachexia associated with chronic conditions including lung cancer (LC). ...
  • Del Hoyo Soriano, Laura; Xicota Vila, Laura, 1987-; Sánchez Benavides, Gonzalo; Cuenca Royo, Aida Ma, 1981-; Sola Llopis, Susana de; Langohr, Klaus; Fagundo, Ana B.; Farré Albaladejo, Magí; Dierssen, Mara; Torre Fornell, Rafael de la (Frontiers, 2015)
    Down syndrome (DS) is an intellectual disability (ID) disorder in which language and specifically, verbal fluency are strongly impaired domains; nearly all adults show neuropathology of Alzheimer's disease (AD), including ...
  • Rodríguez-Morató, Jose, 1987-; Goday Arno, Alberto; Langohr, Klaus; Pujadas Bastardes, Mitona; Civit, Ester; Pérez Mañá, Clara; Papaseit Fontanet, Esther; Ramon, Jose Manuel; Benaiges Foix, David; Castañer, Olga; Farré Albaladejo, Magí; Torre Fornell, Rafael de la (Nature Research, 2019)
    Morbid obesity and bariatric surgery induce anatomical, physiological and metabolic alterations that may alter the body's disposition of drugs. Current literature on this topic is limited and sometimes inconsistent. ...
  • Del Hoyo Soriano, Laura; Xicota Vila, Laura, 1987-; Langohr, Klaus; Sánchez Benavides, Gonzalo; Sola Llopis, Susana de; Cuenca Royo, Aida Ma, 1981-; Rodríguez, Joan; Rodríguez-Morató, Jose, 1987-; Farré Albaladejo, Magí; Dierssen, Mara; Torre Fornell, Rafael de la; The TESDAD Study Group (Frontiers, 2016)
    Down syndrome (DS) is an aneuploidy syndrome that is caused by trisomy for human chromosome 21 resulting in a characteristic cognitive and behavioral phenotype, which includes executive functioning and adaptive behavior ...