Browsing by Author "Langohr, Klaus"

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  • Torrens Cánovas, Carlos; Marí, Raquel; Cuenca, Marta; Ferrer, Tulia; Langohr, Klaus; Santana Pérez, Fernando (Elsevier, 2018)
    The objective of this study is to analyze the effect of different imaging modalities in treatment decision making in proximal humeral fractures. After evaluation of 116 consecutive proximal humeral fractures, observers ...
  • Pastor, Antonio; Fernández Aranda, Fernando; Fitó Colomer, Montserrat; Jiménez Murcia, Susana; Botella, Cristina; Fernández Real, Jose M.; Frühbeck, Gema; Tinahones Madueño, Francisco José; Fagundo, Ana B.; Rodríguez Rodríguez, Juan Francisco; Agüera, Zaida; Langohr, Klaus; Casanueva, Felipe F.; Torre Fornell, Rafael de la (Public Library of Science , 2016)
    The endocannabinoid (eCB) system can promote food intake by increasing odor detection in mice. The eCB system is over-active in human obesity. Our aim is to measure circulating eCB concentrations and olfactory capacity in ...
  • Sola Llopis, Susana de; Torre Fornell, Rafael de la; Sánchez Benavides, Gonzalo; Benejam, Bessy; Cuenca Royo, Aida Ma, 1981-; Del Hoyo Soriano, Laura; Rodríguez, Joan; Catuara Solarz, Silvina, 1986-; Sánchez Gutiérrez, Judit; Dueñas-Espín, Iván, 1979-; Hernández, Gimena; Peña-Casanova, J. (Jordi); Langohr, Klaus; Videla, Sebastià; Blehaut, Henry; Farré Albaladejo, Magí; Dierssen, Mara; TESDAD Study Group (Frontiers, 2015)
    The recent prospect of pharmaceutical interventions for cognitive impairment of Down syndrome (DS) has boosted a number of clinical trials in this population. However, running the trials has raised some methodological ...
  • Fonseca Casals, Francina, 1972-; Mestre-Pintó, Juan Ignacio; Rodríguez-Minguela, Rocío; Papaseit Fontanet, Esther; Pérez Mañá, Clara; Langohr, Klaus; Barbuti, Margherita; Farré Albaladejo, Magí; Torrens, Marta; Neurodep Group (Frontiers, 2022)
    Background: Major depressive disorder (MDD) and cocaine use disorder (CUD) are related with disability and high mortality rates. The assessment and treatment of psychiatric comorbidity is challenging due to its high ...
  • Boronat Rigol, Anna, 1990-; Mateus Rodriguez, Julian Andrés; Soldevila-Domenech, Natalia; Guerra, Mercè; Rodríguez-Morató, Jose, 1987-; Varon, Carlota; Muñoz Aguayo, Daniel; Barbosa, Francina; Morales, Juan Carlos; Gaedigk, Andreas; Langohr, Klaus; Covas Planells, Maria Isabel; Pérez Mañá, Clara; Fitó Colomer, Montserrat; Tyndale, Rachel F.; Torre Fornell, Rafael de la (Elsevier, 2019)
    Introduction: The simple phenol hydroxytyrosol (OHTyr) has been associated with the beneficial health effects of extra virgin olive oil. Pre-clinical studies have identified Tyr hydroxylation, mediated by cytochrome P450 ...
  • Pardo Lozano, Ricardo; Farré Albaladejo, Magí; Yubero Lahoz, Samanta, 1985-; O'Mathuna, Brian; Torrens, Marta; Mustata, Cristina; Pérez Mañá, Clara; Langohr, Klaus; Cuyàs, Elisabet; Carbó Banús, Marcel·lí; Torre Fornell, Rafael de la (Public Library of Science (PLoS), 2012)
    The synthetic psychostimulant MDMA (±3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). ...
  • Catuara Solarz, Silvina, 1986-; Espinosa-Carrasco, José; Erb, Ionas; Langohr, Klaus; Gonzalez, Juan Ramon; Notredame, Cedric; Dierssen, Mara (Society for Neuroscience, 2016)
    Intellectual disability in Down syndrome (DS) is accompanied by altered neuro-architecture, deficient synaptic plasticity, and excitation-inhibition imbalance in critical brain regions for learning and memory. Recently, ...
  • Martin Casals, Miquel; Gutiérrez Martos, Miriam, 1989-; Cabrera Ortega, Roberto; Langohr, Klaus; Maldonado, Rafael, 1961-; Farré Albaladejo, Magí; Torre Fornell, Rafael de la (Springer, 2021)
    Rationale: Cocaine addiction is a chronic relapsing disorder that lacks of an effective treatment. Isoflavones are a family of compounds present in different plants and vegetables like soybeans that share a common chemical ...
  • Boronat Rigol, Anna, 1990-; Mateus Rodriguez, Julian Andrés; Soldevila-Domenech, Natalia; Guerra Albà, Mercè; Rodríguez-Morató, Jose, 1987-; Varon, Carlota; Muñoz, Daniel; Barbosa, Francina; Morales, Juan Carlos; Gaedigk, Andreas; Langohr, Klaus; Covas Planells, Maria Isabel; Pérez Mañá, Clara; Fitó Colomer, Montserrat; Tyndale, Rachel F.; Torre Fornell, Rafael de la (Elsevier, 2019)
    Here we present new and original data on the endogenous conversion of tyrosol (Tyr) into hydroxytyrosol (OHTyr) in humans and its effects on the cardiovascular system. A randomized, crossover, controlled clinical trial was ...
  • Pérez Mañá, Clara; Mateus Rodriguez, Julian Andrés; Díaz-Pellicer, Patricia; Díaz-Baggerman, Ariadna; Pérez, Marta; Pujadas Bastardes, Mitona; Fonseca Casals, Francina, 1972-; Papaseit Fontanet, Esther; Pujol, Jesús; Langohr, Klaus; Torre Fornell, Rafael de la (Oxford University Press, 2022)
    Background: Energy drinks (EDs) reduce sleepiness and fatigue and improve driving performance whereas alcohol does just the opposite. Although it is a trendy combination among young people, the effects of alcohol mixed ...
  • Gomez-Gomez, Àlex; Aguilera, Paula; Langohr, Klaus; Casals, Gregori; Pavon, Cristina; Marcos del Águila, Josep, 1971-; To-Figueras, Jordi; Pozo Mendoza, Óscar J., 1975- (MDPI, 2022)
    Acute intermittent porphyria (AIP) is an inherited rare hepatic disorder due to mutations within the hydroxymethylbilane gene. AIP patients with active disease overproduce aminolevulinic acid (ALA) and porphobilinogen (PBG) ...
  • Udina, M. ; Navinés, Ricard; Egmond, E.  ; Oriolo, Giovanni; Langohr, Klaus; Gimenez, Dolors; Valdés, M. ; Gómez-Gil, E. ; Grande, Iria; Gratacós Mayora, Mònica; Kapczinski, F.  ; Artigas, Francesc; Vieta, Eduard; Solà, Rosa; Martín Santos, Rocío (Oxford University Press, 2016)
    BACKGROUND: The role of inflammation in mood disorders has received increased attention. There is substantial evidence that cytokine therapies, such as interferon alpha (IFN-alpha), can induce depressive symptoms. Indeed, ...
  • Cuyàs, Elisabet; Verdejo García, Antonio; Fagundo, Ana B.; Khymenets, Olha, 1974-; Rodríguez, Joan; Cuenca Royo, Aida Ma, 1981-; De Sola Llopis, Susana; Langohr, Klaus; Peña-Casanova, J. (Jordi); Torrens, Marta; Martín Santos, Rocío; Farré Albaladejo, Magí; Torre Fornell, Rafael de la (Public Library of Science (PLoS), 2011)
    This study is aimed to clarify the association between MDMA cumulative use and cognitive dysfunction, and the potential role of candidate genetic polymorphisms in explaining individual differences in the cognitive effects ...
  • Soldevila-Domenech, Natalia; Boronat Rigol, Anna, 1990-; Langohr, Klaus; Torre Fornell, Rafael de la (Frontiers, 2019)
    Longer life expectancy has led to an increase in the prevalence of age-related cognitive decline and dementia worldwide. Due to the current lack of effective treatment for these conditions, preventive strategies represent ...
  • Pérez Mañá, Clara; Farré Albaladejo, Magí; Pastor, Antonio; Fonseca Casals, Francina, 1972-; Torrens, Marta; Menoyo Colomer, Esther; Pujadas Bastardes, Mitona; Frias, Silvia; Langohr, Klaus; Torre Fornell, Rafael de la (Oxford University Press, 2017)
    AIMS: Ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) are non-oxidative metabolites of alcohol that can be detected in conventional and non-conventional biological matrices for longer periods than alcohol. The ...
  • Goday Arno, Alberto; Farré Albaladejo, Magí; Rodríguez-Morató, Jose, 1987-; Ramón Moros, José Manuel; Pérez Mañá, Clara; Papaseit Fontanet, Esther; Civit, Ester; Langohr, Klaus; Carbó Banús, Marcel·lí; Benaiges Foix, David; Castañer, Olga; Flores-Le-Roux, Juana Antonia; Pera Roman, Manuel Ramón; Grande Posa, Luís; Torre Fornell, Rafael de la (Springer, 2017)
    PURPOSE: The purpose of the study was to study the impact of the two most common bariatric surgery techniques on paracetamol pharmacokinetics (a marker of gastric emptying) and caffeine metabolism (a marker of liver ...
  • Catuara Solarz, Silvina, 1986-; Espinosa-Carrasco, José; Erb, Ionas; Langohr, Klaus; Notredame, Cedric; González Ruiz, Juan Ramón; Dierssen, Mara (Frontiers, 2015)
    Down syndrome (DS) individuals present increased risk for Alzheimer's disease (AD) neuropathology and AD-type dementia. Here, we investigated the use of green tea extracts containing (-)-epigallocatechin-3-gallate (EGCG), ...
  • Chacón Cabrera, Alba, 1988-; Mateu-Jimenez, Mercè; Langohr, Klaus; Fermoselle Pérez, Clara, 1985-; García-Arumí, Elena; Andreu, Antoni; Yélamos López, José; Barreiro Portela, Esther (Wiley, 2017)
    Strategies to treat cachexia are still at its infancy. Enhanced muscle protein breakdown and ubiquitin-proteasome system are common features of cachexia associated with chronic conditions including lung cancer (LC). ...
  • Cieuta-Walti, Cécile; Cuenca Royo, Aida Ma, 1981-; Langohr, Klaus; López-Vílchez, María Ángeles; García García, Jordi; Aldea-Perona, Ana; Forcano, Laura; Gomis González, Maria, 1988-; Torre Fornell, Rafael de la; PERSEUS Study Group (Elsevier, 2022)
    Purpose: although some caregivers are using epigallocatechin gallate (EGCG) off label in hopes of improving cognition in young adults with Down syndrome (DS), nothing is known about its safety, tolerability, and efficacy ...
  • Del Hoyo Soriano, Laura; Xicota Vila, Laura, 1987-; Sánchez Benavides, Gonzalo; Cuenca Royo, Aida Ma, 1981-; Sola Llopis, Susana de; Langohr, Klaus; Fagundo, Ana B.; Farré Albaladejo, Magí; Dierssen, Mara; Torre Fornell, Rafael de la (Frontiers, 2015)
    Down syndrome (DS) is an intellectual disability (ID) disorder in which language and specifically, verbal fluency are strongly impaired domains; nearly all adults show neuropathology of Alzheimer's disease (AD), including ...

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