Browsing by Author "La Porta, Carmen, 1985-"

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  • Effects of pregabalin on the nociceptive, emotional and cognitive manifestations of neuropathic pain in mice
    La Porta, Carmen, 1985-; Lara Mayorga, Itzel Montserrat, 1982-; Negrete Buela, Roger; Maldonado, Rafael, 1961- (Wiley, 2016)
    BACKGROUND: Preclinical drug discovery for the treatment of chronic pain is at present challenged by the difficulty to study behaviours comparable to the complex human pain experience in animals. Several reports have ...
  • Involvement of the endocannabinoid system in osteoarthritis pain
    La Porta, Carmen, 1985- (Universitat Pompeu Fabra, 2015-10-15)
    Chronic pain is a major clinical problem producing huge economic and social burdens. Currently, chronic pain treatment has limited efficacy and significant side effects. One of the reasons of this unmet clinical need is ...
  • Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate
    La Porta, Carmen, 1985-; Bura, S. Andreea, 1978-; Aracil Fernández, Auxiliadora; Manzanares, Jorge; Maldonado, Rafael, 1961- (Elsevier, 2013)
    Joint pain is a common clinical problem for which both inflammatory and degenerative joint diseases are major causes. The purpose of this study was to investigate the role of CB1 and CB2 cannabinoid receptors in the ...
  • Role of the endocannabinoid system in a mouse model of Fragile X undergoing neuropathic pain
    Ramírez López, Angela; Pastor, Antonio; Torre Fornell, Rafael de la; La Porta, Carmen, 1985-; Ozaita Mintegui, Andrés, 1969-; Cabañero Ferri, David; Maldonado, Rafael, 1961- (Wiley, 2021)
    Background: Neuropathic pain is a complex condition characterized by sensory, cognitive and affective symptoms that magnify the perception of pain. The underlying pathogenic mechanisms are largely unknown and there is an ...
  • Role of the endocannabinoid system in the emotional manifestations of osteoarthritis pain
    La Porta, Carmen, 1985-; Bura, S. Andreea, 1978-; Llorente Onaindia, Jone; Pastor, Antonio; Navarrete, Francisco; García-Gutiérrez, María S.; Torre Fornell, Rafael de la; Manzanares, Jorge; Monfort, Jordi; Maldonado, Rafael, 1961- (Lippincott Williams & Wilkins, 2015)
    In this study, we investigated the role of the endocannabinoid system (ECS) in the emotional and cognitive alterations associated with osteoarthritis pain. The monosodium iodoacetate model was used to evaluate the affective ...