Browsing by Author "López Otín, Carlos"

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  • Comparative analysis of cancer genes in the human and chimpanzee genomes
    Puente, Xosé S.; Velasco, Gloria; Gutiérrez Fernández, Ana; Bertranpetit, Jaume, 1952-; King, Mary Claire; López Otín, Carlos (BioMed Central, 2006)
    Background: Cancer is a major medical problem in modern societies. However, the incidence of this disease in non-human primates is very low. To study whether genetic differences between human and chimpanzee could contribute ...
  • Giant tortoise genomes provide insights into longevity and age-related disease
    Quesada, Víctor; Kuderna, Lukas F.K.; Marquès i Bonet, Tomàs, 1975-; López Otín, Carlos (Nature Research, 2019)
    Giant tortoises are among the longest-lived vertebrate animals and, as such, provide an excellent model to study traits like longevity and age-related diseases. However, genomic and molecular evolutionary information on ...
  • The novel evolution of the sperm whale genome
    Warren, Wesley C.; Kuderna, Lukas F.K.; Alexander, Alana; Catchen, Julian; Pérez Silva, José G.; López Otín, Carlos; Quesada, Víctor; Minx, Patrick; Tomlinson, Chad; Montague, Michael J.; Farias, Fabiana; Walter, Ronald B.; Marquès i Bonet, Tomàs, 1975-; Glenn, Travis; Kieran, Troy John; Wise, Sandra S.; Wise, John Pierce; Waterhouse, Robert M. (Oxford University Press, 2017)
    The sperm whale, made famous by Moby Dick, is one of the most fascinating of all ocean-dwelling species given their unique life history, novel physiological adaptations to hunting squid at extreme ocean depths, and their ...