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Browsing by Author "López Montesinos, Inmaculada"

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A case-control study of the clinical and economic impact of infections caused by Carbapenemase-producing Enterobacterales (CPE)

López Montesinos, Inmaculada; Carot, Aina; Milagro Montero, Maria; Sorli Redó, M. Luisa; Siverio-Parès, Ana; Esteban-Cucó, Sandra; Duran Jordà, Xavier, 1974-; Gómez-Zorrilla, Silvia; Horcajada Gallego, Juan Pablo (Taylor & Francis, 2024)

Purpose: The aim was to analyse the clinical and economic impact of carbapenemase-producing Enterobacterales (CPE) infections. Methods: Case-control study. Adult patients with CPE infections were considered cases, while ...
A large multicenter prospective study of community-onset healthcare associated bacteremic urinary tract infections in the era of multidrug resistance: even worse than hospital acquired infections?

Gómez-Zorrilla, Silvia; López Montesinos, Inmaculada; Horcajada Gallego, Juan Pablo; REIPI/GEIRAS-GEMARA SEIMC ITUBRAS-2 Group (SpringerOpen, 2021)

Introduction: Healthcare-associated (HCA) infections represent a growing public health problem. The aim of this study was to compare community-onset healthcare associated (CO-HCA) bacteremic urinary tract infections (BUTI) ...
Aminoglycoside or polymyxin monotherapy for treating complicated urinary tract infections caused by extensively drug-resistant pseudomonas aeruginosa: a propensity score-adjusted and matched cohort study

López Montesinos, Inmaculada; Gómez-Zorrilla, Silvia; Palacios-Baena, Zaira Raquel; Prim, Núria; Echeverría Esnal, Daniel; Gracia Arnillas, María Pilar; Montero, Maria Milagro; Duran Jordà, Xavier, 1974-; Sendra, Elena; Sorli Redó, M. Luisa; Güerri Fernández, Roberto; Padilla, Eduardo; Grau Cerrato, Santiago; Horcajada Gallego, Juan Pablo; PROA PSMAR group (SpringerOpen, 2022)

Introduction: extensively drug-resistant (XDR) Pseudomonas aeruginosa (PA) infections are difficult to treat. We aimed to compare aminoglycosides or polymyxin monotherapy versus other antibiotic regimens (carbapenems, ...
Ceftolozane-tazobactam: when, how and why using it?

López Montesinos, Inmaculada; Montero, Maria Milagro; Sorli Redó, M. Luisa; Horcajada Gallego, Juan Pablo (Sociedad Española de Quimioterapia, 2021)

Ceftolozane-tazobactam is currently the most active antipseudomonal agent, including multidrug-resistant extensively drug-resistant strains. Tazobactam provides additional activity against many extended-spectrum beta-lactamases ...
Characteristics and outcomes of patients with COVID-19 with and without prevalent hypertension: a multinational cohort study

Reyes, Carlen; Sorlí, Luisa; López Montesinos, Inmaculada; Duarte Salles, Talita, 1985- (BMJ Publishing Group, 2021)

Objective: To characterise patients with and without prevalent hypertension and COVID-19 and to assess adverse outcomes in both inpatients and outpatients. Design and setting: This is a retrospective cohort study using 15 ...
Clinical and economic burden of community-onset multidrug-resistant infections requiring hospitalization

López Montesinos, Inmaculada; Domínguez-Guasch, A.; Gómez-Zorrilla, Silvia; Duran Jordà, Xavier, 1974-; Siverio, Ana; Arenas-Miras, María Del Mar; Montero, Maria Milagro; Sorli Redó, M. Luisa; Grau Cerrato, Santiago; Horcajada Gallego, Juan Pablo (Elsevier, 2020)

Objectives: To analyze the clinical and economic burden of community-acquired (CA) or community-onset healthcare-associated (COHCA) multidrug-resistant (MDR) infections requiring hospitalization. Methods: Case-control ...
Comparative analysis of complicated urinary tract infections caused by extensively drug-resistant pseudomonas aeruginosa and extended-spectrum β-lactamase-producing klebsiella pneumoniae

Sendra, Elena; López Montesinos, Inmaculada; Rodríguez-Alarcón, Alicia; Du, Juan; Siverio-Parès, Ana; Arenas-Miras, María Del Mar; Cañas-Ruano, Esperanza; Prim, Núria; Duran Jordà, Xavier, 1974-; Blasco-Hernando, Fabiola; García-Alzórriz, Enric; Cots Reguant, Francesc; Ferrández, Olivia; Gómez-Zorrilla, Silvia (MDPI, 2022)

The objective was to compare clinical characteristics, outcomes, and economic differences in complicated urinary tract infections (cUTI) caused by extensively drug-resistant Pseudomonas aeruginosa (XDR P. aeruginosa) and ...
Comparative analysis of dalbavancin versus other antimicrobial options for gram-positive cocci infections: effectiveness, hospital stay and mortality

Horcajada Gallego, Juan Pablo; de Pablo-Miró, Mar; Pujol-Ruiz¸ Sergi; Iftimie, Simona Mihaela; Arenas-Miras, María Del Mar; López Montesinos, Inmaculada; Duran Jordà, Xavier, 1974-; Anglès, Albert; Grau Cerrato, Santiago; Horcajada Gallego, Juan Pablo (MDPI, 2021)

Dalbavancin is a new antibiotic that is effective against Gram-positive microorganisms, including methicillin-resistant Staphylococci, and offers the possibility of administering intravenous therapy once weekly in an ...
Comparison of Ceftolozane/Tazobactam infusion regimens in a hollow-fiber infection model against extensively drug-resistant pseudomonas aeruginosa isolates

Montero, Maria Milagro; Domene Ochoa, Sandra; López-Causapé, Carla; López Montesinos, Inmaculada; Luque Pardos, Sònia; Sorli Redó, M. Luisa; Campillo Ambrós, Núria; Padilla, Eduardo; Prim, Núria; Ferrer Alapont, Lorena; Grau Cerrato, Santiago; Oliver, Antoni; Horcajada Gallego, Juan Pablo (ASM Press, 2022)

The aim of this study was to compare the efficacy of intermittent (1-h), extended (4-h), and continuous ceftolozane-tazobactam (C/T) infusion against three extensively drug-resistant (XDR) sequence type (ST) 175 P. aeruginosa ...
Comparison of hospitalized COVID-19 and influenza patients requiring supplemental oxygen in a cohort study: clinical impact and resource consumption

López Montesinos, Inmaculada; Arrieta Aldea, Itziar; Dicastillo, Aitor; Zuccarino, Flavio; Sorli Redó, M. Luisa; Güerri Fernández, Roberto; Arnau-Barrés, Isabel; Milagro Montero, Maria; Siverio-Parès, Ana; Duran Jordà, Xavier, 1974-; Arenas-Miras, María Del Mar; Brasé Arnau, Ariadna; Cañas-Ruano, Esperanza; Castañeda, Silvia; Kamber, Ignacio Domingo; Gómez Junyent, Joan; Pelegrín, Iván; Sánchez Martínez, Francisca; Sendra, Elena; Suaya Leiro, Lucía; Villar García, Judit; Nogués Solan, Francesc Xavier; Grau Cerrato, Santiago; Knobel Freud, Hernando; Gómez-Zorrilla, Silvia; Horcajada Gallego, Juan Pablo; COVID-MAR Group (Oxford University Press, 2022)

Background: To compare clinical characteristics, outcomes, and resource consumption of patients with COVID-19 and seasonal influenza requiring supplemental oxygen. Methods: Retrospective cohort study conducted at a ...
European society of Clinical Microbiology and Infectious Diseases guidelines on diagnosis and treatment of brain abscess in children and adults

Bodilsen, Jacob; D′Alessandris, Quintino Giorgio; Humphreys, Hilary; Iro, Mildred Adaku; Klein, Matthias; Last, Katharina; López Montesinos, Inmaculada; Pagliano, Pasquale; Sipahi, Oguz Resat; San-Juan, Rafael; Tattevin, Pierre; Thurnher, Majda; Treviño-Rangel, Rogelio de J.; Brouwer, Matthijs C.; ESCMID Study Group for Infections of the Brain (ESGIB) (Elsevier, 2024)

Scope: These European Society of Clinical Microbiology and Infectious Diseases guidelines are intended for clinicians involved in diagnosis and treatment of brain abscess in children and adults. Methods: Key questions were ...
Evaluation of the host immune response assay SeptiCyte RAPID for potential triage of COVID-19 patients

Montero, Maria Milagro; Hardy-Werbin, Max; Gonzalez-Gallardo, Soledad; Torres, Erica; Rueda, Rebeca; Arenas-Miras, María Del Mar; Arietta-Aldea, Itziar; Castañeda, Silvia; Gómez Junyent, Joan; Gómez-Zorrilla, Silvia; Guerri-Fernandez, Robert; Sánchez-Martínez, Francesca; López Montesinos, Inmaculada; Pelegrín, Iván; Sendra, Elena; Sorlí, Luisa; Villar García, Judit; Bellosillo Paricio, Beatriz; Horcajada Gallego, Juan Pablo (Nature Research, 2023)

Tools for the evaluation of COVID-19 severity would help clinicians with triage decisions, especially the decision whether to admit to ICU. The aim of this study was to evaluate SeptiCyte RAPID, a host immune response assay ...
High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement

Montero, Maria Milagro; Mir Fontana, M. Luisa; Sulleiro, Elena; Avalos Esquivel, J.L.; García López, E.; Molina-Morant, D.; López Montesinos, Inmaculada; Sorli Redó, M. Luisa; Veliz Espinosa, G.; Mounteis Oliva, E.; Crespo Barrio, Marta; Monge, I.; Horcajada Gallego, Juan Pablo; Grau Cerrato, Santiago; Pascual Santos, Julio (Elsevier, 2019)

There is little published data on benznidazole dosing, or levels in cerebrospinal fluid. In this report, we describe the clinical course of an immunosuppressed patient with Chagas central nervous system involvement. He was ...
Impact of a nosocomial COVID-19 outbreak on a non-COVID-19 nephrology ward during the first wave of the pandemic in Spain

Montero, Maria Milagro; Hidalgo López, Carlota; López Montesinos, Inmaculada; Sorli Redó, M. Luisa; Barrufet González, Cristina; Villar García, Judit; Güerri Fernández, Roberto; Herranz, Milagros; Crespo Barrio, Marta; Arenas Jiménez, María Dolores; Pascual Santos, Julio; González Juanes, Cristina; Horcajada Gallego, Juan Pablo (MDPI, 2021)

Introduction: The aim of this study was to analyze a nosocomial coronavirus disease 2019 (COVID-19) outbreak that occurred on a polyvalent non-COVID-19 ward at a tertiary care university hospital in Spain during the first ...
Individuals with higher CD4/CD8 ratio exhibit increased risk of acute respiratory distress syndrome and in-hospital mortality during acute SARS-CoV-2 infection

Pascual-Dapena, Ana; Chillarón Jordan, Juan José; Llauradó Cabot, Gemma; Arnau-Barrés, Isabel; Flores-Le-Roux, Juana Antonia; López Montesinos, Inmaculada; Sorli Redó, M. Luisa; Martínez-Pérez, Juan Luis; Gómez-Zorrilla, Silvia; Du, Juan; García-Giralt, Natalia; Güerri Fernández, Roberto (Frontiers, 2022)

Background: CD4/CD8 ratio has been used as a quantitative prognostic risk factor in patients with viral infections. This study aims to assess the association between in-hospital mortality and at admission CD4/CD8 ratio ...
Low zinc levels at admission associates with poor clinical outcomes in SARS-CoV-2 infection

Vogel-González, Marina; Talló Parra, Marc, 1992-; Herrera-Fernández, Víctor; Pérez Vilaró, Gemma, 1985-; Chillón, Miguel; Nogués Solan, Francesc Xavier; Gómez-Zorrilla, Silvia; López Montesinos, Inmaculada; Arnau-Barrés, Isabel; Sorli Redó, M. Luisa; Horcajada Gallego, Juan Pablo; García-Giralt, Natalia; Pascual Santos, Julio; Díez Antón, Juana, 1962-; Vicente García, Rubén, 1978-; Güerri Fernández, Roberto (MDPI, 2021)

Background: Zinc is an essential micronutrient that impacts host-pathogen interplay at infection. Zinc balances immune responses, and also has a proven direct antiviral action against some viruses. Importantly, zinc ...
Oral and intravenous fosfomycin in complicated urinary tract infections

López Montesinos, Inmaculada; Horcajada Gallego, Juan Pablo (Sociedad Española de Quimioterapia, 2019)

Urinary tract infections are one of the most common health problems and entail a high consumption of health system resources. Due to the increase in global antibiotic resistances in recent years, it is increasingly common ...
Prevalence and prognostic value of myocardial injury in the initial presentation of SARS-CoV-2 infection among older adults

Arnau-Barrés, Isabel; Pascual-Dapena, Ana; López Montesinos, Inmaculada; Gómez-Zorrilla, Silvia; Sorli Redó, M. Luisa; Herrero, Marta; Nogués Solan, Francesc Xavier; Montero, Milagros; Vázquez Ibar, Olga; García-Giralt, Natalia; Miralles Basseda, Ramon; Güerri Fernández, Roberto (MDPI, 2021)

Myocardial involvement during SARS-CoV-2 infection has been reported in many prior publications. We aim to study the prevalence and the clinical implications of acute myocardial injury (MIN) during SARS-CoV-2 infection, ...
Risk factors and clinical impact of multidrug resistance in healthcare-associated bacteraemic urinary tract infections: a post-hoc analysis of a multicentre prospective cohort in Spain

Gómez-Zorrilla, Silvia; Sendra, Elena; López Montesinos, Inmaculada; Duran Jordà, Xavier, 1974-; Horcajada Gallego, Juan Pablo; ITUBRAS-2 Group (Elsevier, 2024)

Background: The global burden associated with antimicrobial resistance is of increasing concern. Aim: To evaluate risk factors associated with multidrug-resistant (MDR) infection and its clinical impact in a cohort of ...
Risk Factors for mortality among patients with pseudomonas aeruginosa bloodstream infections: what is the influence of XDR phenotype on outcomes?

Montero, Maria Milagro; López Montesinos, Inmaculada; Knobel Freud, Hernando; Molas, Ema; Sorli Redó, M. Luisa; Siverio, Ana; Prim, Núri; Segura, Concepción; Duran Jordà, Xavier, 1974-; Grau Cerrato, Santiago; Horcajada Gallego, Juan Pablo (MDPI, 2020)

This study aimed to assess the impact of extensively drug-resistant (XDR) phenotype on mortality in Pseudomonas aeruginosa bacteremia. A retrospective cohort study was performed in a tertiary hospital from January 2000 to ...

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