Browsing by Author "Kollmorgen, Gwendlyn"

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  • Cacciaglia, Raffaele; Salvadó, Gemma; Molinuevo, José Luis; Shekari, Mahnaz; Falcón, Carles; Operto, Grégory; Suárez-Calvet, Marc; Milà Alomà, Marta; Sala, Arianna; Rodriguez-Vieitez, Elena; Kollmorgen, Gwendlyn; Suridjan, Ivonne; Blennow, Kaj; Zetterberg, Henrik; Gispert López, Juan Domingo; Alzheimer’s Disease Neuroimaging Initiative; ALFA Study (Nature Research, 2022)
    Amyloid (Aβ) pathology is the earliest detectable pathophysiological event along the Alzheimer's continuum, which can be measured both in the cerebrospinal fluid (CSF) and by Positron Emission Tomography (PET). Yet, these ...
  • Milà Alomà, Marta; Salvadó, Gemma; Gispert López, Juan Domingo; Vilor Tejedor, Natàlia, 1988-; Grau-Rivera, Oriol; Sala Vila, Aleix; Sánchez Benavides, Gonzalo; Arenaza Urquijo, Eider M.; Crous-Bou, Marta; González de Echávarri, José Maria; Minguillón, Carolina; Fauria, Karine; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Suárez-Calvet, Marc; Molinuevo, José Luis; ALFA Study (Wiley, 2020)
    Introduction: The biological pathways involved in the preclinical stage of the Alzheimer's continuum are not well understood. Methods: We used NeuroToolKit and Elecsys® immunoassays to measure cerebrospinal fluid (CSF) ...
  • Sánchez Benavides, Gonzalo; Suárez-Calvet, Marc; Milà Alomà, Marta; Arenaza Urquijo, Eider M.; Grau-Rivera, Oriol; Operto, Grégory; Domingo Gispert, Juan; Vilor Tejedor, Natàlia, 1988-; Sala Vila, Aleix; Crous-Bou, Marta; González de Echávarri, José Maria; Minguillón, Carolina; Fauria, Karine; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Molinuevo, José Luis; ALFA Study (Elsevier, 2021)
    Neurofilament light chain (NfL) is an axonal protein that when measured in cerebrospinal fluid (CSF) serves as a biomarker of neurodegeneration. We aimed at investigating the association among CSF NfL, presence of Subjective ...
  • Grau-Rivera, Oriol; Navalpotro Gómez, Irene; Sánchez Benavides, Gonzalo; Suárez-Calvet, Marc; Milà Alomà, Marta; Arenaza Urquijo, Eider M.; Salvadó, Gemma; Sala Vila, Aleix; Shekari, Mahnaz; González de Echávarri, José Maria; Minguillón, Carolina; Niñerola-Baizán, Aida; Perissinotti, Andrés; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Gispert López, Juan Domingo; Molinuevo, José Luis; ALFA Study (BioMed Central, 2021)
    Background: Recognizing clinical manifestations heralding the development of Alzheimer's disease (AD)-related cognitive impairment could improve the identification of individuals at higher risk of AD who may benefit from ...
  • Pelkmans, Wiesje; Shekari, Mahnaz; Brugulat Serrat, Anna, 1986-; Sánchez Benavides, Gonzalo; Minguillón, Carolina; Fauria, Karine; Molinuevo, José Luis; Grau-Rivera, Oriol; González Escalante, Armand; Kollmorgen, Gwendlyn; Carboni, Margherita; Ashton, Nicholas J.; Zetterberg, Henrik; Blennow, Kaj; Suárez-Calvet, Marc; Gispert López, Juan Domingo; ALFA Study (Wiley, 2024)
    Introduction: We studied how biomarkers of reactive astrogliosis mediate the pathogenic cascade in the earliest Alzheimer's disease (AD) stages. Methods: We performed path analysis on data from 384 cognitively unimpaired ...
  • Salvadó, Gemma; Milà Alomà, Marta; Shekari, Mahnaz; Minguillón, Carolina; Fauria, Karine; Niñerola-Baizán, Aida; Perissinotti, Andrés; Kollmorgen, Gwendlyn; Buckley, Christopher, 1948-; Farrar, Gill; Zetterberg, Henrik; Blennow, Kaj; Suárez-Calvet, Marc; Molinuevo, José Luis; Gispert López, Juan Domingo; ALFA Study (Wiley, 2021)
    Introduction: The association between cerebral amyloid-β accumulation and downstream CSF biomarkers is not fully understood, particularly in asymptomatic stages. Methods: In 318 cognitively unimpaired participants, we ...
  • Milà Alomà, Marta; Brinkmalm, Ann; Ashton, Nicholas J.; Kvartsberg, Hlin; Shekari, Mahnaz; Operto, Grégory; Salvadó, Gemma; Falcon, Carles; Domingo Gispert, Juan; Vilor Tejedor, Natàlia, 1988-; Arenaza Urquijo, Eider M.; Grau-Rivera, Oriol; Sala Vila, Aleix; Sanchez-Benavides, Gonzalo; González de Echávarri, José Maria; Minguillón, Carolina; Fauria, Karine; Niñerola-Baizán, Aida; Perissinotti, Andrés; Kollmorgen, Gwendlyn; Suridjan, Ivonne; Zetterberg, Henrik; Molinuevo, José Luis; Blennow, Kaj; Suárez-Calvet, Marc; ALFA Study (Lippincott Williams & Wilkins, 2021)
    Background and objectives: To determine whether CSF synaptic biomarkers are altered in the early preclinical stage of the Alzheimer continuum and associated with Alzheimer disease (AD) risk factors, primary pathology, and ...
  • Brugulat Serrat, Anna, 1986-; Cañas-Martínez, Alba; Canals-Gispert, Lidia; Marne, Paula; Gramunt Fombuena, Nina; Suárez-Calvet, Marc; Arenaza Urquijo, Eider M.; Grau-Rivera, Oriol; González de Echávarri, José Maria; Minguillón, Carolina; Fauria, Karine; Kollmorgen, Gwendlyn; Suridjan, Ivonne; Zetterberg, Henrik; Blennow, Kaj; Gispert López, Juan Domingo; Molinuevo, José Luis; Sánchez Benavides, Gonzalo; ALFA Study (IOS Press, 2021)
    Background: Cognitive performance of a given individual should be interpreted in the context of reference standards obtained in cognitively healthy populations. Recent evidence has shown that removing asymptomatic individuals ...
  • Johnson, Sterling C.; Suárez-Calvet, Marc; Suridjan, Ivonne; Minguillón, Carolina; Gispert López, Juan Domingo; Jonaitis, Erin; Michna, Agatha; Carboni, Margherita; Bittner, Tobias; Rabe, Christina; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj (BioMed Central, 2023)
    Background: Alzheimer's disease (AD) is a complex and heterogeneous disease, which requires reliable biomarkers for diagnosis and monitoring disease activity. Preanalytical protocol and technical variability associated ...
  • Vilor Tejedor, Natàlia, 1988-; Ciampa, Iacopo; Operto, Grégory; Falcón, Carles; Suárez-Calvet, Marc; Crous-Bou, Marta; Shekari, Mahnaz; Arenaza Urquijo, Eider M.; Milà Alomà, Marta; Grau-Rivera, Oriol; Minguillón, Carolina; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Guigó Serra, Roderic; Molinuevo, José Luis; Gispert López, Juan Domingo; ALFA Study (BioMed Central, 2021)
    Background: Perivascular spaces (PVS) have an important role in the elimination of metabolic waste from the brain. It has been hypothesized that the enlargement of PVS (ePVS) could be affected by pathophysiological mechanisms ...
  • Akinci, Muge; Peña-Gómez, Cleofé; Operto, Grégory; Fuentes-Julian, Sherezade; Deulofeu, Carme; Sánchez Benavides, Gonzalo; Milà Alomà, Marta; Grau-Rivera, Oriol; Gramunt Fombuena, Nina; Navarro i Cuartiellas, Arcadi, 1969-; Minguillón, Carolina; Fauria, Karine; Suridjan, Ivonne; Kollmorgen, Gwendlyn; Bayfield, Anna; Blennow, Kaj; Zetterberg, Henrik; Molinuevo, José Luis; Suárez-Calvet, Marc; Gispert López, Juan Domingo; Arenaza-Urquijo, Eider M.; ALFA Study (Lippincott Williams & Wilkins, 2022)
    Background and objectives: Increased anxious-depressive symptomatology is observed in the preclinical stage of Alzheimer disease (AD), which may accelerate disease progression. We investigated whether β-amyloid, cortical ...

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