Browsing by Author "Knobel Freud, Hernando"

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  • Latorre, Irene; Leidinger, Petra; Backes, Christina; Domínguez, Jose; de Souza-Galvao, Malú; Maldonado, Jose; Prat, Cristina; Ruiz, Juan Jesús; Sánchez Martínez, Francisca; Casas, Irma; Keller, Andreas; Briesen, Hagen von; Knobel Freud, Hernando; Meese, Eckart; Meyerhans, Andreas (European Respiratory Society, 2015)
    Background: Deregulation of microRNAs (miRNAs)has been associated with various human pathologies including bacterial infections.Aim: To investigate the role of miRNAs as blood biomarkers for the diagnosis of active pulmonary ...
  • Troya, Jesús; Knobel Freud, Hernando; Imaz, Arkaitz; GESIDA-8314 Study Group (Public Library of Science (PLoS) , 2016)
    OBJECTIVES: Based on data from clinical practice, we evaluated the effectiveness and safety of switching to abacavir/lamivudine plus rilpivirine (ABC/3TC+RPV) treatment in virologically suppressed HIV-1-infected patients. ...
  • Soldado Folgado, Jade; Chillarón Jordan, Juan José; Cañas-Ruano, Esperanza; Arrieta Aldea, Itziar; González Mena, Alicia; Blasco-Hernando, Fabiola; Knobel Freud, Hernando; García-Giralt, Natalia; Güerri Fernández, Roberto (MDPI, 2022)
    Long-term non-progressors (LTNPs) are HIV-infected individuals (HIV+) whose viral replication is controlled. However, these individuals experience complications associated with HIV, among them, bone remodeling impairment. ...
  • Bernardino, Jose I.; Mocroft, Amanda; Wallet, Cedrick; de Wit, Stéphane; Katlama, Christine; Reiss, Peter; Mallon, Patrick W.; Richert, Laura; Molina, Jean-Michel; Knobel Freud, Hernando; Morlat, Philippe; Babiker, Abdel; Pozniac, Anton; Raffi, Francois; Arribas, José Ramón; NEAT001/ANRS143 Trial Study Group (Public Library of Science (PLoS), 2019)
    BACKGROUND: Comparison of changes in body composition, adipokines and inflammatory markers after initial therapy with a nucleos(t)ide reverse transcriptase inhibitor (N(t)RTI)- sparing or containing regimen are scarce. ...
  • Martín-Iguacel, Raquel; Vázquez-Friol, María del Carmen; Burgos Cibrian, Joaquin; Reyes-Urueña, Juliana; Moreno Fornés, Sergio; Aceitón Cardona, Jordi; Díaz, Yesika; Domingo, Pere; Saumoy, Maria; Knobel Freud, Hernando; Dalmau Juanola, David; Borjabad, Beatriz; Johansen, Isik Somuncu; Miró, Josep M.; Casabona, Jordi; Llibre, Josep M. (Frontiers, 2023)
    Objectives: People with HIV (PWH) have a higher cardiovascular risk than the general population. It remains unclear, however, whether the risk of cardiovascular disease (CVD) is higher in late HIV presenters (LP; CD4 ≤ 350 ...
  • Tiraboschi, Juan M.; Knobel Freud, Hernando; Imaz, Arkaitz; Villar García, Judit; Ferrer, Elena; Saumoy, Maria; González Mena, Alicia; Rozas, Nerea; Vila, Antonia; Niubó, Jordi; Curto, Jordi; Daniel Podzamczer (International Medical Press, 2016)
    BACKGROUND: Lopinavir/ritonavir (LPV/r) monotherapy is used in selected virologically suppressed HIV-infected patients. Some would prefer a once-daily (OD) dose instead of the usual twice-daily dose to favour adherence. ...
  • Soldado Folgado, Jade; Rins-Lozano, Oriol; Arrieta Aldea, Itziar; González Mena, Alicia; Cañas-Ruano, Esperanza; Knobel Freud, Hernando; Garcia Giralt, Natàlia (Frontiers, 2023)
    Background: The impact of tenofovir disoproxil fumarate (TDF) antiretroviral (ART) regimens on bone health has been characterized mostly by bone mineral density (BMD), but recently also by bone quality (BQ). The aim of ...
  • López Montesinos, Inmaculada; Arrieta Aldea, Itziar; Dicastillo, Aitor; Zuccarino, Flavio; Sorli Redó, M. Luisa; Güerri Fernández, Roberto; Arnau-Barrés, Isabel; Milagro Montero, Maria; Siverio-Parès, Ana; Duran Jordà, Xavier, 1974-; Arenas-Miras, María Del Mar; Brasé Arnau, Ariadna; Cañas-Ruano, Esperanza; Castañeda, Silvia; Kamber, Ignacio Domingo; Gómez Junyent, Joan; Pelegrín, Iván; Sánchez Martínez, Francisca; Sendra, Elena; Suaya Leiro, Lucía; Villar García, Judit; Nogués Solan, Francesc Xavier; Grau Cerrato, Santiago; Knobel Freud, Hernando; Gómez-Zorrilla, Silvia; Horcajada Gallego, Juan Pablo; COVID-MAR Group (Oxford University Press, 2022)
    Background: To compare clinical characteristics, outcomes, and resource consumption of patients with COVID-19 and seasonal influenza requiring supplemental oxygen. Methods: Retrospective cohort study conducted at a ...
  • Morillo-Verdugo, Ramón; Polo, Rosa; Knobel Freud, Hernando (Sociedad Española de Farmacia Hospitalaria, 2020)
    Adherence to treatment in patients living with HIV remains the focus of attention of health professionals and researchers. However, patient profiles and the available therapeutic arsenal have changed greatly over the last ...
  • Chalouni, Mathieu; Rodríguez-Centeno, Javier; Samri, Assia; Blanco, Julian; Stella-Ascariz, Natalia; Wallet, Cedrick; Knobel Freud, Hernando; Zucman, David; Alejos Ferreras, Belen; Autran, Brigitte; Thiebaut, Rodolphe; Raffi, François; Arribas, José Ramón; NEAT 001/ANRS 143 Trial Study Group (Public Library of Science (PLoS), 2020)
    In 31 participants who started first-line antiretroviral therapy in the NEAT 001/ANRS 143 clinical trial, we found after 96 weeks a statistically significant increase in blood telomere length (TL) of 0.04 (T/S Ratio) (p = ...
  • Rivero, Antonio; Pérez-Molina, José Antonio; Blasco, Antonio Javier; Arribas, José Ramón; Crespo, Manuel; Domingo, Pere; Estrada, Vicente; Iribarren, José Antonio; Knobel Freud, Hernando; Lázaro, Pablo; López-Aldeguer, José; Lozano, Fernando; Moreno, Santiago; Palacios, Rosario; Pineda, Juan Antonio; Pulido, Federico; Rubio, Rafael; Torre, Javier de la; Tuset, Montserrat; Gatell, Josep M. (Elsevier, 2017)
    Introducción: El panel de expertos de GESIDA/Plan Nacional del Sida ha recomendado pautas preferentes (PP), pautas alternativas (PA) y otras pautas (OP) para el tratamiento antirretroviral (TARV) como terapia de inicio en ...
  • Acin, Pablo; Luque Pardos, Sònia; Subirana Cachinero, Isaac; Vila, Joan; Fernández-Sala, Xènia; Guelar Grinberg, Ana; Antonio, Marta de; Arrieta Aldea, Itziar; Knobel Freud, Hernando (Mary Ann Liebert, Inc, 2023)
    Several patient-related factors that influence adherence to antiretroviral therapy (ART) have been described. However, studies that propose a practical and simple tool to predict nonadherence after ART initiation are still ...
  • Rubio, Rafael; Knobel Freud, Hernando; Von Wichmann, Miguel Angel; GESIDA/SEIMC Writing Committee (Elsevier, 2016)
    A pesar del gran avance que ha supuesto el tratamiento antirretroviral (TAR) para el pronóstico de la infección por el VIH, las infecciones oportunistas (IO) continúan siendo causa de morbilidad y mortalidad ...
  • Garcia de Olalla, Patricia; Molas, Ema; Barberà, María Jesús; Martín, Silvia; Arellano, Encarnació; Gosch, Mercè; Saladie, Pilar; Carbonell, Teresa; Knobel Freud, Hernando; Díez, Elia; Caylà i Busqueras, Joan A. (Public Library of Science, 2015)
    BACKGROUND: An estimated 30% of HIV cases in the European Union are not aware of their serological status. This study aimed to assess the effectiveness of a pilot HIV partner notification program. METHODS: HIV cases diagnosed ...
  • Martí-Pastor, Marc; Garcia de Olalla, Patricia; Barberà, María Jesús; Manzardo, Christian; Ocaña, Inma; Knobel Freud, Hernando; Gurguí, Mercè; Humet, Victoria; Vall, Martí; Ribera, Esteban; Villar García, Judit; Martin-Ezquerra, Gemma; Sambeat, Maria A.; Marco, Andrés; Vives, Alvaro; Alsina, Mercè; Mir, Josep M.; Caylà i Busqueras, Joan A.; HIV Surveillance Group (BioMed Central, 2015)
    BACKGROUND: The aim of this study was to determine the evolution of HIV infection, gonorrhea, syphilis and lymphogranuloma venereum (LGV), and their epidemiological characteristics in Barcelona city. METHODS: Population-based ...
  • De Antonio Cuscó, Marta; Parrilla, F.J.; Knobel Freud, Hernando; Echeverría Esnal, Daniel; Castellví Font,A.; Vázquez, Ana; Masclans Enviz, Joan Ramon; Ferrández, Olivia; Grau Cerrato, Santiago (Sociedad Española de Quimioterapia, 2022)
  • Gutierrez-San-Juan, Júlia; Arrieta Aldea, Itziar; Arnau-Barrés, Isabel; García-Escobar, Greta; Lerma-Chippirraz, Elisabet; Pérez-García, Paula; Marcos, Agustin; Blasco-Hernando, Fabiola; González Mena, Alicia; Cañas-Ruano, Esperanza; Knobel Freud, Hernando; Güerri Fernández, Roberto (BioMed Central, 2022)
    Objective: The HIV infection is a chronic disease that causes neurocognitive impairment (NI) and has been related with early development of frailty. We aimed to study the main risk factors for neurocognitive disorders and ...
  • Molas, Ema; Luque Pardos, Sònia; Retamero, A.; Echeverría Esnal, Daniel; Guelar Grinberg, Ana; Montero, Maria Milagro; Güerri Fernández, Roberto; Sorli Redó, M. Luisa; Lerma-Chippirraz, Elisabet; Villar García, Judit; Knobel Freud, Hernando (Taylor & Francis (Routledge), 2018)
    OBJECTIVES: Interactions between antiretroviral treatment (ART) and comedications are a concern in HIV-infected patients. This study aimed to determine the frequency and severity of potential drug-drug interactions (PDDIs) ...
  • Meseguer Donlo, Javier; Soldado Folgado, Jade; Du, Juan; González Mena, Alicia; Blasco-Hernando, Fabiola; Cañas-Ruano, Esperanza; Nogués Solan, Francesc Xavier; Knobel Freud, Hernando; Garcia Giralt, Natàlia; Güerri Fernández, Roberto (Elsevier, 2023)
    Background: HIV infection produces a chronic inflammation which leads to early aging of people living with HIV. Even though antiretroviral treatments (ART) have significantly increased HIV patient survival, an underlying ...
  • Villar García, Judit; Güerri Fernández, Roberto; Moya, Andrés; González Mena, Alicia; Hernández, Juan José; Lerma-Chippirraz, Elisabet; Guelar Grinberg, Ana; Sorli Redó, M. Luisa; Horcajada Gallego, Juan Pablo; Artacho, Alejandro; D´Auria, Giuseppe; Knobel Freud, Hernando (Public Library of Science (PLoS), 2017)
    Dysbalance in gut microbiota has been linked to increased microbial translocation, leading to chronic inflammation in HIV-patients, even under effective HAART. Moreover, microbial translocation is associated with insufficient ...

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