Browsing by Author "Knobel, Philip A."

Sort by: Order: Results:

  • GEMC1 is a critical regulator of multiciliated cell differentiation.
    Terré, Berta; Piergiovanni, Gabriele; Segura-Bayona, Sandra; Gil Gómez, Gabriel; Youssef, Sameh A.; Attolini, Camille Stephan-Otto; Wilsch-Bräuninger, Michaela; Jung, Carole; Rojas Mendoza, Ana Maria; Marjanovi c, Marko; Knobel, Philip A.; Palenzuela, Lluís; López-Rovira, Teresa; Forrow, Stephen; Huttner, Wieland B.; Valverde, M. A. (Miguel Ángel), 1963-; de Bruin, Alain; Costanzo, Vincenzo; Stracker, Travis (EMBO Press, 2016)
    The generation of multiciliated cells (MCCs) is required for the proper function of many tissues, including the respiratory tract, brain, and germline. Defects in MCC development have been demonstrated to cause a subclass ...
  • Mitochondrial protein synthesis and mtDNA levels coordinated through an aminoacyl-tRNA synthetase subunit
    Picchioni, Daria; Antolin-Fontes, Albert; Camacho, Noelia; Schmitz, Claus; Pons-Pons, Alba; Rodríguez-Escribà, Marta; Machallekidou, Antoni; Güler, Merve Nur; Siatra, Panagiota; Carretero-Junquera, Maria; Serrano, Alba; Hovde, Stacy L.; Knobel, Philip A.; Novoa, Eva Maria; Solà-Vilarrubias, Maria; Kaguni, Laurie S.; Stracker, Travis; Ribas de Pouplana, Lluís (Elsevier, 2019)
    The aminoacylation of tRNAs by aminoacyl-tRNA synthetases (ARSs) is a central reaction in biology. Multiple regulatory pathways use the aminoacylation status of cytosolic tRNAs to monitor and regulate metabolism. The ...
  • PARP-1/PARP-2 double deficiency in mouse T cells results in faulty immune responses and T lymphomas
    Navarro, Judith; Gozalbo-López, Beatriz; Méndez, Andrea C.; Dantzer, Françoise; Schreiber, Valérie; Martínez, Carlos; Arana, David M.; Farrés, Jordi; Revilla-Nuin, Beatriz; Bueno, María F.; Ampurdanés, Coral; Galindo-Campos, Miguel A.; Knobel, Philip A.; Segura-Bayona, Sandra; Martin-Caballero, Juan; Stracker, Travis; Aparicio, Pedro; Del Val, Margarita; Yélamos López, José (Nature Publishing Group, 2017)
    The maintenance of T-cell homeostasis must be tightly regulated. Here, we have identified a coordinated role of Poly(ADP-ribose) polymerase-1 (PARP-1) and PARP-2 in maintaining T-lymphocyte number and function. Mice bearing ...