Browsing by Author "Klonizakis, Antonios"

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  • SEGCOND predicts putative transcriptional condensate-associated genomic regions by integrating multi-omics data
    Klonizakis, Antonios; Nikolaou, Christoforos; Graf, T. (Thomas) (Oxford University Press, 2023)
    Motivation: The compartmentalization of biochemical reactions, involved in the activation of gene expression in the eukaryotic nucleus, leads to the formation of membraneless bodies through liquid-liquid phase separation. ...
  • The trophectoderm acts as a niche for the inner cell mass through C/EBPα-regulated IL-6 signaling
    Plana-Carmona, Marcos; Stik, Grégoire; Bulteau, Romain; Segura-Morales, Carolina; Alcázar, Noelia; Wyatt, Christopher Douglas Robert, 1988-; Klonizakis, Antonios; Andrés Aguayo, Luisa de; Gasnier, Maxime; Tian, Tian V.; Torcal Garcia, Guillem, 1991-; Vila-Casadesús, Maria; Plachta, Nicolas; Serrano, Manuel; Francesconi, Mirko; Graf, T. (Thomas) (Elsevier, 2022)
    IL-6 has been shown to be required for somatic cell reprogramming into induced pluripotent stem cells (iPSCs). However, how Il6 expression is regulated and whether it plays a role during embryo development remains unknown. ...