Visualitza per autoria "Kleinjans, Jos C."

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  • Birth weight, head circumference, and prenatal exposure to acrylamide from maternal diet: The European prospective mother-child study (NewGeneris)
    Sunyer Deu, Jordi; Pedersen, Marie; Stedingk, Hans von; Botsivali, Maria; Agramunt, Silvia; Alexander, Jan; Brunborg, Gunnar; Chatzi, Leda; Fleming, Sarah; Fthenou, Eleni; Granum, Berit; Gutzkow, Kristine B.; Hardie, Laura J.; Knudsen, Lisbeth E.; Kyrtopoulos, Sosterios A.; Mendez, Michelle A.; Merlo, Domenico Franco; Nielsen, Jeanette K.; Rydberg, Per; Segerbäck, Dan; Wright, John; Törnqvist, Margareta; Kleinjans, Jos C.; Kogevinas, Manolis; NewGeneris Consortium (National Institute of Environmental Health Sciences (NIEHS), 2012)
    Background: Acrylamide is a common dietary exposure that crosses the human placenta. It is classified as a probable human carcinogen, and developmental toxicity has been observed in rodents. Objectives: We examined the ...
  • DNA methylation profiling implicates exposure to PCBs in the pathogenesis of B-cell chronic lymphocytic leukemia
    Georgiadis, Panagiotis; Gavriil, Marios; Rantakokko, Panu; Ladoukakis, Efthymios; Botsivali, Maria; Kelly, Rachel S.; Bergdahl, Ingvar A.; Kiviranta, Hannu; Vermeulen, Roel; Spaeth, Florentin; Hebbels, Dennie G. A. J.; Kleinjans, Jos C.; Kok, Theo M. de; Palli, Domenico; Vineis, Paolo; Kyrtopoulos, Sosterios A.; EnviroGenomarkers consortium (Elsevier, 2019)
    Objectives: To characterize the impact of PCB exposure on DNA methylation in peripheral blood leucocytes and to evaluate the corresponding changes in relation to possible health effects, with a focus on B-cell lymphoma. ...
  • Embracing the dark side: computational approaches to unveil the functionality of genes lacking biological annotation in drug-induced liver injury
    Souza, Terezinha; Panuwat, Trairatphisan; Piñero González, Janet, 1977-; Furlong, Laura I., 1971-; Saez-Rodriguez, Julio; Kleinjans, Jos C.; Jennen, Danyel (Frontiers, 2018)
    In toxicogenomics, functional annotation is an important step to gain additional insights into genes with aberrant expression that drive pathophysiological mechanisms. Nevertheless, there exists a gap on annotation of these ...
  • Short-term exposure to traffic-related air pollution reveals a compound-specific circulating miRNA profile indicating multiple disease risks
    Krauskopf, Julian; van Veldhoven, Karin; Chadeau-Hyam, Marc; Vermeulen, Roel; Carrasco Turigas, Glòria; Nieuwenhuijsen, Mark J.; Vineis, Paolo; Kok, Theo M. de; Kleinjans, Jos C. (Elsevier, 2019)
    Traffic-related air pollution (TRAP) is a complex mixture of compounds that contributes to the pathogenesis of many diseases including several types of cancer, pulmonary, cardiovascular and neurodegenerative diseases, and ...

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