Browsing by Author "Kiefer, Kerstin, 1986-"

Sort by: Order: Results:

  • Ceramide imbalance and impaired TLR4-Mediated autophagy in BMDM of an ORMDL3-overexpressing mouse model
    Kiefer, Kerstin, 1986-; Casas, Josefina; García López, Roberto, 1991-; Vicente García, Rubén, 1978- (MDPI, 2019)
    Increased orosomucoid-like 3 (ORMDL3) expression levels, due to single nucleotide polymorphisms (SNPs), have been associated with several inflammatory diseases, including asthma and inflammatory bowel diseases. ORMDL ...
  • Implication of the disease-associated ORMDL3 in macrophage physiology
    Kiefer, Kerstin, 1986- (Universitat Pompeu Fabra, 2016-05-12)
    Genome-wide association studies linked increased ORMDL3 expression levels to several inflammatory diseases via single nucleotide polymorphisms. However, the pathophysiological mechanisms underlying this association are ...
  • Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21
    Carreras Sureda, Amado, 1986-; Rubio Moscardó, Fanny; Olvera, Alex; Argilaguet Marqués, Jordi, 1977-; Kiefer, Kerstin, 1986-; Mothe, Beatriz; Meyerhans, Andreas; Brander, Christian; Vicente García, Rubén, 1978- (Public Library of Science (PLoS), 2016)
    Single nucleotide polymorphisms (SNPs) located in the chromosome region 17q12-q21 are risk factors for asthma. Particularly, there are cis-regulatory haplotypes within this region that regulate differentially the expression ...
  • The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism
    Matalonga, Jonathan; Kiefer, Kerstin, 1986-; Vicente García, Rubén, 1978-; Valledor, Annabel F. (Elsevier, 2017)
    Macrophages exert potent effector functions against invading microorganisms but constitute, paradoxically, a preferential niche for many bacterial strains to replicate. Using a model of infection by Salmonella Typhimurium, ...
  • TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells
    Mitrovic, Sandra; Nogueira, Cristina; Cantero Recasens, Gerard, 1984-; Kiefer, Kerstin, 1986-; Fernández-Fernández, José Manuel, 1967-; Popoff, Jean-François; Casano, Laetitia; Bard, Frederic A.; Gómez, Raul; Valverde, M. A. (Miguel Ángel), 1963-; Malhotra, Vivek (eLife, 2013)
    Mucin 5AC (MUC5AC) is secreted by goblet cells of the respiratory tract and, surprisingly, also expressed de novo in mucus secreting cancer lines. siRNA-mediated knockdown of 7343 human gene products in a human colonic ...