Browsing by Author "Keil, Thomas"

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  • The development of the MeDALL core questionnaires for a harmonized follow-up assessment of eleven European birth cohorts on asthma and allergies
    Hohmann, Cynthia; Pinart, Mariona; Torrent Quetglas, Maties; Esplugues, Ana; Sunyer Deu, Jordi; Antó i Boqué, Josep Maria; Keil, Thomas; The MeDALL Study Group (Karger (S. Karger AG), 2014)
    Background: Numerous birth cohorts have been initiated in the world over the past 30 years using heterogeneous methods to assess the incidence, course and risk factors of asthma and allergies. The aim of the present work ...
  • Distinction between rhinitis alone and rhinitis with asthma using interactomics
    Aguilar, Daniel; Lemonnier, Nathanael; Melén, Erik; Bustamante Pineda, Mariona; Gruzieva, Olena; Guerra, Stefano; Keil, Thomas; Koppelman, Gerard H.; Celedón, Juan C.; Antó i Boqué, Josep Maria; Bousquet, Jean (Nature Research, 2023)
    The concept of "one-airway-one-disease", coined over 20 years ago, may be an over-simplification of the links between allergic diseases. Genomic studies suggest that rhinitis alone and rhinitis with asthma are operated by ...
  • Early-life house dust mite allergens, childhood mite sensitization, and respiratory outcomes.
    Casas, Lidia; Sunyer Deu, Jordi; Tischer, Christina; Gehring, Ulrike; Wickman, Magnus; García Esteban, Raquel; Lehmann, Irina; Kull, Inger; Reich, Andreas; Lau, Susanne; Wijga, Alet; Antó i Boqué, Josep Maria; Nawrot, Tim S.; Heinrich, Joachim; Keil, Thomas; Torrent Quetglas, Maties (Wiley, 2015)
    BACKGROUND: Exposure to indoor allergens during early life may play a role in the development of the immune system and inception of asthma. OBJECTIVE: To describe the house dust mite (HDM) allergen concentrations in bedroom ...
  • Environmental exposure assessment in European birth cohorts: results from the ENRIECO project
    Gehring, Ulrike; Casas Sanahuja, Maribel; Brunekreef, Bert; Bergström, Anna; Bonde, Jens Peter; Botton, Jérémie; Chévrier, Cecile; Cordier, Sylvaine; Heinrich, Joachim; Hohmann, Cynthia; Keil, Thomas; Sunyer Deu, Jordi; Tischer, Christina; Toft, Gunnar; Wickman, Magnus; Vrijheid, Martine; Nieuwenhuijsen, Mark J. (BioMed Central, 2013)
    Environmental exposures during pregnancy and early life may have adverse health effects. Single birth cohort studies often lack statistical power to tease out such effects reliably. To improve the use of existing data and ...
  • Is there a sex-shift in prevalence of allergic rhinitis and comorbid asthma from childhood to adulthood? A meta-analysis
    Fröhlich, Matthias; Pinart, Mariona; Keller, Theresa; Reich, Andreas; Cabieses, Báltica; Hohmann, Cynthia; Postma, Dirkje S.; Bousquet, Jean; Antó i Boqué, Josep Maria; Keil, Thomas; Roll, Stephanie (BioMed Central, 2017)
    BACKGROUND: Allergic rhinitis and asthma as single entities affect more boys than girls in childhood but more females in adulthood. However, it is unclear if this prevalence sex-shift also occurs in allergic rhinitis and ...
  • Phenotyping asthma, rhinitis, and eczema in MeDALL population-based birth cohorts: an allergic comorbidity cluster
    García Aymerich, Judith; Benet, Marta; Saeys, Y.; Pinart, Mariona; Basagaña Flores, Xavier; Smit, Henriëtte A.; Siroux, Valérie; Just, Jocelyne; Momas, Isabelle; Rancière, Fanny; Keil, Thomas; Hohmann, Cynthia; Lau, Susanne; Wahn, Ulrich; Heinrich, Joachim; Tischer, Christina; Fantini, Maria Pia; Lenzi, Jacopo; Porta, Daniela; Koppelman, Gerard H.; Postma, Dirkje S.; Berdel, Dietrich; Koletzko, Sibylle; Kerkhof, Marjan; Gehring, Ulrike; Wickman, Magnus; Melén, Erik; Hallberg, Jenny; Bindslev Jensen, Carsten; Eller, Esben; Kull, Inger; Lodrup Carlsen, Karin C.; Carlsen, Kai-Håkon; Lambrecht, Bart N.; Kogevinas, Manolis; Sunyer Deu, Jordi; Kauffmann, Francine; Bousquet, Jean; Antó i Boqué, Josep Maria (Wiley, 2015)
    BACKGROUND: Asthma, rhinitis and eczema often co-occur in children, but their interrelationships at the population level have been poorly addressed. We assessed co-occurrence of childhood asthma, rhinitis and eczema using ...
  • Sex-specific incidence of asthma, rhinitis and respiratory multimorbidity before and after puberty onset: individual participant meta-analysis of five birth cohorts collaborating in MeDALL
    Hohmann, Cynthia; Keller, Theresa; Gehring, Ulrike; Wijga, Alet; Standl, Marie; Kull, Inger; Bergström, Anna; Lehmann, Irina; von Berg, Andrea; Heinrich, Joachim; Lau, Susanne; Wahn, Ulrich; Maier, Dieter; Antó i Boqué, Josep Maria; Bousquet, Jean; Smit, Henriëtte A.; Keil, Thomas; Roll, Stephanie (BMJ Publishing Group, 2019)
    Introduction To understand the puberty-related sex shift in the prevalence of asthma and rhinitis as single entities and as respiratory multimorbidities, we investigated if there is also a sex-specific and puberty-related ...
  • Specific IgE and IgG measured by the MeDALL allergen-chip depend on allergen and route of exposure: The EGEA study
    Siroux, Valérie; Lupinek, Christian; Resch, Yvonne; Curin, Mirela; Just, Jocelyne; Keil, Thomas; Kiss, Renata; Lodrup Carlsen, Karin C.; Melén, Erik; Nadif, Rachel; Pin, Isabelle; Skrindo, Ingebjorg; Vrtala, Susanne; Wickman, Magnus; Antó i Boqué, Josep Maria; Valenta, Rudolf; Bousquet, Jean (Elsevier, 2017)
    Background: The nature of allergens and route and dose of exposure may affect the natural development of IgE and IgG responses. Objective: We sought to investigate the natural IgE and IgG responses toward a large panel of ...
  • The Sex-shift in single disease and multimorbid asthma and rhinitis during puberty - a study by MeDALL
    Keller, Theresa; Hohmann, Cynthia; Standl, Marie; Wijga, Alet; Gehring, Ulrike; Melén, Erik; Almqvist, Catarina; Lau, Susanne; Eller, Esben; Wahn, Ulrich; Christiansen, E.S.; von Berg, Andrea; Heinrich, Joachim; Lehmann, Irina; Maier, Dieter; Postma, Dirkje S.; Antó i Boqué, Josep Maria; Bousquet, Jean; Keil, Thomas; Roll, Stephanie (Wiley, 2018)
    Background - Cross‐sectional studies suggested that allergy prevalence in childhood is higher in boys compared to girls, but it remains unclear whether this inequality changes after puberty. We examined the sex‐specific ...

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