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Browsing by Author "Kaplan, Allen P."

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Chronic spontaneous urticaria. Focus on pathophysiology to unlock treatment advances

Kaplan, Allen P.; Lebwohl, Mark; Giménez Arnau, Anna Maria; Hide, Michihiro; Armstrong, April W.; Maurer, Marcus (Wiley, 2023)

Chronic spontaneous urticaria (CSU) is a debilitating skin disease characterized by intensely itchy wheals, angioedema, or both. Symptoms recur spontaneously, on a near-daily basis, over >6 weeks; many patients experience ...
Mechanisms of action that contribute to efficacy of omalizumab in chronic spontaneous urticaria

Kaplan, Allen P.; Giménez Arnau, Anna Maria; Saini, Sarbjit S. (Wiley, 2017)

The monoclonal anti-immunoglobulin E (IgE) antibody, omalizumab, was the first drug approved for use in patients with chronic idiopathic/spontaneous urticaria (CIU/CSU) who remain symptomatic despite H1 -antihistamine ...
Similar Efficacy with Omalizumab in Chronic Idiopathic/Spontaneous Urticaria Despite Different Background Therapy.

Casale, Thomas B.; Bernstein, Jonathan A.; Maurer, Marcus; Saini, Sarbjit S.; Trzaskoma, Benjamin; Chen, Hubert; Clive, Grattan; Giménez Arnau, Anna Maria; Kaplan, Allen P.; Rosén, Karin (Elsevier, 2015)

BACKGROUND: Data from the 3 omalizumab pivotal trials in patients with chronic idiopathic urticaria/chronic spontaneous urticaria (CIU/CSU) represent the largest database of patients reported to date with refractory disease ...
The pathogenesis of chronic spontaneous urticaria: the role of infiltrating cells

Giménez Arnau, Anna Maria; DeMontojoye, Laurence; Asero, Riccardo; Cugno, Massimo; Kulthanan, Kanokvalai; Yanase, Yuhki; Hide, Michihiro; Kaplan, Allen P. (Elsevier, 2021)

Chronic spontaneous urticaria is characterized by a perivascular non-necrotizing cellular infiltrate around small venules of the skin. It consists primarily of CD4(+) lymphocytes, a prominence of the T helper (Th)2 subtype ...

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Browsing by Author "Kaplan, Allen P."

Browsing by Author "Kaplan, Allen P."

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