Browsing by Author "Jené i Sanz, Alba, 1984-"

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  • Inhibition of specific NF-KB activity contributes to the tumor suppressor function of 14-3-3omega in breast cancer
    Inglés Esteve, Julia; Morales, Mònica; Dalmases Massegú, Alba, 1982-; Garcia Carbonell, Ricard; Jené i Sanz, Alba, 1984-; López Bigas, Núria; Iglesias Coma, Mar; Ruiz Herguido, Cristina; Rovira Guerín, Ana; Rojo, Federico; Albanell Mestres, Joan; Gomis, Roger R.; Bigas Salvans, Anna; Espinosa Blay, Lluís (Public Library of Science (PLoS), 2012)
    14-3-3σ is frequently lost in human breast cancers by genetic deletion or promoter methylation. We have now investigated the involvement of 14-3-3σ in the termination of NF-κB signal in mammary cells and its putative role ...
  • IntOGen - Arrays
    Gundem, Gunes; Pérez Llamas, Christian, 1976-; Jené i Sanz, Alba, 1984-; Kedzierska, Anna; Islam, Abul, 1978-; Déu Pons, Jordi; Furney, Simon J.; López Bigas, Núria (Universitat Pompeu Fabra, 2010-02)
    Genes and pathways affected by expression and copy number changes in tumors across projects and cancer types.
  • IntOGen - Cancer driver database (2013)
    González-Pérez, Abel; Pérez Llamas, Christian, 1976-; Déu Pons, Jordi; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Jené i Sanz, Alba, 1984-; Santos, Alberto; López Bigas, Núria (Universitat Pompeu Fabra, 2013-05)
    Mutations, genes and pathways involved in tumorigenesis across 4,623 cancer genomes/exomes from 13 cancer sites. IntOGen-mutations identifies cancer drivers across tumor types. Nature Methods 10, 2013, doi:10.1038/nmeth.2642
  • IntOGen - Pipeline
    González-Pérez, Abel; Pérez Llamas, Christian, 1976-; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Jené i Sanz, Alba, 1984-; Santos, Alberto; López Bigas, Núria; Déu Pons, Jordi (Universitat Pompeu Fabra, 2016-07-18)
    Analyses somatic mutations in thousands of tumor genomes to identify cancer driver genes.
  • IntOGen-mutations identifies cancer drivers across tumor types
    Gonzalez-Perez, Abel; Pérez Llamas, Christian, 1976; Deu Pons, Jordi; Tamborero Noguera, David; Schroeder, Michael Philipp,1986-; Jené i Sanz, Alba, 1984-; Santos, Alberto; López Bigas, Núria (Nature Research, 2013)
    The IntOGen-mutations platform (http://www.intogen.org/mutations/) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 ...
  • The mutational landscape of chromatin regulatory factors across 4,623 tumor samples
    González-Pérez, Abel; Jené i Sanz, Alba, 1984-; López Bigas, Núria (BioMed Central, 2013)
    Background: Chromatin regulatory factors are emerging as important genes in cancer development and are regarded as interesting candidates for novel targets for cancer treatment. However, we lack a comprehensive understanding ...

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