Browsing by Author "Izpisúa Belmonte, J. C."

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  • A protocol describing the genetic correction of somatic human cells and subsequent generation of IPS cell
    Rodríguez Pizà, Ignasi; Raya Chamorro, Ángel; Navarro, Susanna; Izpisúa Belmonte, J. C.; Bueren, Juan; Consiglio, Antonella; Sánchez Danés, Adriana, 1984-; Guenechea, Guillermo; Richaud Patin, Yvonne (Nature Publishing Group, 2010)
    The generation of patient-specific induced pluripotent stem cells (iPSCPSCPSCs) offers unprecedented opportunities for modeling and treating human disease. In combination with gene therapy, the iPSCPSCPSC technology can ...
  • Derivation of human embryonic stem cells at the center for regenerative medicine in Barcelona
    Rodríguez Pizà, Ignasi; Raya Chamorro, Ángel; Aran, Begoña; Veiga, Anna; Izpisúa Belmonte, J. C.; Barri, Pere N.; Muñoz, Yolanda; Consiglio, Antonella (Springer, 2010)
    We report here the legislative issues related to/nembryo research and human embryonic stem cell (hESC)/nresearch in Spain and the derivation of nine hESC lines at/nthe Center of Regenerative Medicine in Barcelona. You ...
  • Development of xenobiotic-free conditions towards the generation and propagation of clinically-safe human pluripotent stem cells
    Rodríguez Pizà, Ignasi (Universitat Pompeu Fabra, 2011-04-12)
    Les cèl·lules mare embrionàries humanes (hESC) i més recentment les cèl·lules de pluripotència induïda (iPSC) representen una oportunitat sense precedents per al desenvolupament de noves estratègies terapèutiques per ...
  • Disease-corrected haematopoietic progenitors from Fanconi anemia induced pluripotent stem cells
    Rodríguez Pizà, Ignasi; Verma, Inder M.; Veiga, Anna; Aasen, Trond; Izpisúa Belmonte, J. C.; Bueren, Juan; Garreta Bahima, Elena; Tiscornia, Gustavo; Sleep Ronquillo, Eduard; Raya Chamorro, Ángel; Río, Paula; Consiglio, Antonella; Barrero Núñez, María José; Navarro, Susanna; Vassena, Rita; Guenechea, Guillermo (Nature Publishing Group, 2009)
    The generation of induced pluripotent stem (iPS) cells has enabled the derivation of patient-specific pluripotent cells and/nprovided valuable experimental platforms to model human disease. Patient-specific iPS cells are ...
  • Generation of cardiomyocytes from new human embrionic stem cell lines derived from poor-quanlity blastocysts
    Raya Chamorro, Ángel; Rodríguez Pizà, Ignasi; Aran, Begoña; Consiglio, Antonella; Barri, Pere N.; Veiga, Anna; Izpisúa Belmonte, J. C. (Cold Spring Harbor Laboratory Press-CSHL Press, 2008)
    Human embryonic stem (hES) cells represent a potential source for cell replacement therapy of many degenerative diseases. Most frequently, hES cell lines are derived from surplus embryos from assisted reproduction cycles, ...
  • Generation of feeder-free pig induced pluripotent stem cells without Pou5f1
    Montserrat Pulido, Núria; Oñate Monje, Lorena de, 1985-; Garreta Bahima, Elena; González, Federico; Adamo, Antonio; Eguizábal, Cristina; Häfner, Sophia; Vassena, Rita; Izpisúa Belmonte, J. C. (Cognizant Communication Corporation, 2012)
    The pig represents an ideal large-animal model, intermediate between rodents and humans, for the preclinical assessment of emerging cell therapies. As no validated pig embryonic stem (pES) cell lines have been derived so ...
  • Generation of induced pluripotent stem cells from human cord blood cells with only two factors:OCT4 and SOX2
    Giorgetti, Alessandra; Montserrat Pulido, Núria; Rodríguez Pizà, Ignasi; Azqueta, Carmen; Veiga, Anna; Izpisúa Belmonte, J. C. (Nature Publishing Group, 2010)
    Induced pluripotent stem cells (iPSC ) provide an invaluable resource for regenerative medicine as they allow the generation/nof patient-specific progenitors with potential value for cell therapy. However, in many instances, ...
  • Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector
    Rodríguez Pizà, Ignasi; Barragan, Montserrat; González, Federico; Izpisúa Belmonte, J. C.; Batlle Morera, Laura; Vassena, Rita; Montserrat Pulido, Núria; Tiscornia, Gustavo (National Academy of Sciences, 2009)
    Induced pluripotent stem (iPS) cells have generated keen interest/ndue to their potential use in regenerative medicine. They have/nbeen obtained from various cell types of both mice and humans by/nexogenous delivery of ...
  • Reprogramming of human fibroblasts to induced pluripotent stem cells under xeno-free conditions
    Rodríguez Pizà, Ignasi; Vassena, Rita; Richaud Patin, Yvonne; Izpisúa Belmonte, J. C.; Raya Chamorro, Ángel; Veiga, Anna; Barrero Núñez, María José; González, Federico (AlphaMed Press and Wiley-Blackwell, 2010)
    The availability of induced pluripotent stem cells (iPSCs)/nhas created extraordinary opportunities for modeling and/nperhaps treating human disease. However, all reprogramming/nprotocols used to date involve the use of ...
  • The Role of adult stem cells in tumor formation : mutations in Sox2+ cells induce lineage-specific proliferation
    Vázquez Ferrer, Eric (Universitat Pompeu Fabra, 2018-12-12)
    It has been well-established that progressive accumulation of genetic mutations in proto-oncogenes and tumor suppressors induces cancer. However, the early molecular mechanisms leading to tumor initiation remain elusive. ...

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