Browsing by Author "Hughes, David"

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  • Biological processes modulating longevity across primates: a phylogenetic genome-phenome analysis
    Muntané, Gerard; Farré, Xavier; Rodríguez Pérez, Juan Antonio, 1985-; Pegueroles Queralt, Maria Cinta; Hughes, David; Magalhães, João Pedro de; Gabaldón Estevan, Juan Antonio, 1973-; Navarro i Cuartiellas, Arcadi, 1969- (Oxford University Press, 2018)
    Aging is a complex process affecting different species and individuals in different ways. Comparing genetic variation across species with their aging phenotypes will help understanding the molecular basis of aging and ...
  • Evaluating intra- and inter-individual variation in the human placental transcriptome
    Hughes, David; Kircher, Martin; He, Zhisong; Guo, Songtao; Fairbrother, Genevieve; Moreno, Carlos; Khaitovich, Philipp; Stoneking, Mark (BioMed Central, 2015)
    Background. Gene expression variation is a phenotypic trait of particular interest as it represents the initial link between genotype and other phenotypes. Analyzing how such variation apportions among and within groups ...
  • Expanding the geographic characterisation of epstein-barr virus variation through gene-based approaches
    Telford, Marco, 1984-; Hughes, David; Juan, David; Stoneking, Mark; Navarro i Cuartiellas, Arcadi, 1969-; Santpere Baró, Gabriel, 1981- (MDPI, 2020)
    The Epstein-Barr Virus (EBV) infects the vast majority of human individuals worldwide (~90%) and is associated with several diseases, including different types of cancer and multiple sclerosis, which show wide variation ...
  • The genetic impact of an Ebola outbreak on a wild gorilla population
    Fontseré Alemany, Clàudia, 1992-; Frandsen, Peter; Hernández Rodríguez, Jéssica, 1983-; Niemann, Jonas; Scharff-Olsen, Camilla Hjorth; Vallet, Dominique; Le Gouar, Pascaline; Ménard, Nelly; Navarro i Cuartiellas, Arcadi, 1969-; Siegismund, Hans R.; Hvilsom, Christina; Gilbert, M Thomas; Kuhlwilm, Martin; Hughes, David; Marquès i Bonet, Tomàs, 1975- (BioMed Central, 2021)
    Background: Numerous Ebola virus outbreaks have occurred in Equatorial Africa over the past decades. Besides human fatalities, gorillas and chimpanzees have also succumbed to the fatal virus. The 2004 outbreak at the ...
  • The impact of endogenous content, replicates and pooling on genome capture from faecal samples
    Hernández Rodríguez, Jéssica, 1983-; Arandjelovic, Mimi; Lester, Jack; Filippo, Cesare de; Weihmann, Antje; Meyer, Matthias; Angedakin, Samuel; Casals López, Ferran; Navarro i Cuartiellas, Arcadi, 1969-; Vigilant, Linda; Kühl, Hjalmar S.; Langergraber, Kevin; Boesch, Christophe; Hughes, David; Marquès i Bonet, Tomàs, 1975- (Wiley-Blackwell, 2018)
    Target-capture approach has improved over the past years, proving to be very efficient tool for selectively sequencing genetic regions of interest. These methods have also allowed the use of noninvasive samples such as ...