Browsing by Author "Hu, Frank B."

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  • Association between ultra-processed food consumption and gut microbiota in senior subjects with overweight/obesity and metabolic syndrome
    Atzeni, Alessandro; Martínez, María Ángeles; Babio, Nancy; Konstanti, Prokopis; Tinahones Madueño, Francisco José; Vioque, Jesus; Corella, Dolores; Fitó Colomer, Montserrat; Vidal Alaball, Josep; Moreno Indias, Isabel; Pertusa-Martinez, Salvador; Álvarez-Sala, Andrea; Castañer, Olga; Goday Arno, Alberto; Damas-Fuentes, Miguel; Belzer, Clara; Martínez-González, Miguel Ángel, 1957-; Hu, Frank B.; Salas Salvadó, Jordi (Frontiers, 2022)
    The production and consumption of ultra-processed foods (UPF) has increased considerably during the last years worldwide. Collective evidence shows the association between UPF consumption and adverse health outcomes, ...
  • Carbohydrate quality, fecal microbiota and cardiometabolic health in older adults: a cohort study
    Atzeni, Alessandro; Nishi, Stephanie; Babio, Nancy; Belzer, Clara; Konstanti, Prokopis; Vioque, Jesus; Corella, Dolores; Castañer, Olga; Vidal, Josep; Moreno-Indias, Isabel; Torres-Collado, Laura; Asensio, Eva María; Fitó Colomer, Montserrat; Gómez Pérez, Ana María; Arias, Alejandro; Ruiz-Canela, Miguel; Hu, Frank B.; Tinahones Madueño, Francisco José; Salas Salvadó, Jordi (Taylor & Francis, 2023)
    The impact of carbohydrate quality, measured by the carbohydrate quality index (CQI), on gut microbiota and health has been scarcely investigated. The aim of this study was to cross-sectionally and longitudinally explore ...
  • Changes in plasma total saturated fatty acids and palmitic acid are related to pro-inflammatory molecule IL-6 concentrations after nutritional intervention for one year
    Domínguez-López, Inés; Arancibia-Riveros, Camila; Casas, Rosa; Tresserra-Rimbau, Anna; Razquin, Cristina; Martínez-González, Miguel Ángel, 1957-; Hu, Frank B.; Ros, Emilio; Fitó Colomer, Montserrat; Estruch, Ramón; López-Sabater, M. Carmen (Elsevier, 2022)
    Systemic inflammation is associated with an increased risk of non-communicable diseases, such as cardiovascular diseases and diabetes. Circulating fatty acids (FA) are known to be related to these conditions, possibly ...
  • Circulating citric acid cycle metabolites and risk of cardiovascular disease in the PREDIMED study
    Santos-Lozano, José; Ruiz-Canela, Miguel; Razquin, Cristina; Clish, Clary B.; Guasch Ferré, Marta; Babio, Nancy; Corella, Dolores; Gómez-Gracia, Enrique; Fiol, Miquel; Estruch, Ramón; Lapetra, José; Fitó Colomer, Montserrat; Arós, Fernando; Serra-Majem, Luis; Liang, Liming; Martínez, María Ángeles; Toledo, Estefania; Salas Salvadó, Jordi; Hu, Frank B.; Martínez-González, Miguel Ángel, 1957- (Elsevier, 2023)
    Background and aim Plasma citric acid cycle (CAC) metabolites might be likely related to cardiovascular disease (CVD). However, studies assessing the longitudinal associations between circulating CAC-related metabolites ...
  • Lipid metabolic networks, Mediterranean diet and cardiovascular disease in the PREDIMED trial
    Wang, Dong D.; Fitó Colomer, Montserrat; Hu, Frank B. (Oxford University Press, 2018)
    BACKGROUND: Perturbed lipid metabolic pathways may play important roles in the development of cardiovascular disease (CVD). However, existing epidemiological studies have focused more on discovering individual lipid ...
  • Metabolites of glutamate metabolism are associated with incident cardiovascular events in the PREDIMED PREvención con DIeta MEDiterránea (PREDIMED) Trial.
    Zheng, Yan; Hu, Frank B.; Ruiz-Canela, Miguel; Clish, Clary B.; Dennis, Courtney; Salas-Salvadó, Jordi; Hruby, Adela; Liang, Liming; Toledo, Estefania; Corella, Dolores; Ros, Emilio; Fitó Colomer, Montserrat; Gómez-Gracia, Enrique; Arós, Fernando; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Estruch, Ramón; Martínez-González, Miguel Ángel, 1957- (Willey, 2016)
    BACKGROUND: Glutamate metabolism may play a role in the pathophysiology of cardiometabolic disorders. However, there is limited evidence of an association between glutamate-related metabolites and, moreover, changes in ...
  • Metabolites related to purine catabolism and risk of type 2 diabetes incidence; modifying effects of the TCF7L2-rs7903146 polymorphism
    Papandreou, Christopher; Li, Jun; Liang, Liming; Bulló, Mònica; Zheng, Yan; Ruiz-Canela, Miguel; Yu, Edward; Guasch Ferré, Marta; Razquin, Cristina; Clish, Clary B.; Corella, Dolores; Estruch, Ramón; Ros, Emilio; Fitó Colomer, Montserrat; Arós, Fernando; Serra-Majem, Luis; Rosique-Esteban, Nuria; Martínez-González, Miguel Ángel, 1957-; Hu, Frank B.; Salas-Salvadó, Jordi (Nature Research, 2019)
    Studies examining associations between purine metabolites and type 2 diabetes (T2D) are limited. We prospectively examined associations between plasma levels of purine metabolites with T2D risk and the modifying effects ...
  • Plasma acylcarnitines and risk of cardiovascular disease: effect of Mediterranean diet interventions
    Guasch Ferré, Marta; Zheng, Yan; Ruiz-Canela, Miguel; Martínez-González, Miguel Ángel, 1957-; Corella, Dolores; Estruch, Ramón; Ros, Emilio; Fitó Colomer, Montserrat; Dennis, Courtney; Morales-Gil, Isabel M.; Arós, Fernando; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Hu, Frank B.; Salas-Salvadó, Jordi; Hruby, Adela; Clish, Clary B. (American Society for Nutrition, 2017)
    BACKGROUND: Previous studies have suggested that metabolite profiles of elevated acylcarnitines were associated with increased risk of cardiovascular disease (CVD) in populations with established coronary disease. However, ...
  • Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study
    Yu, Edward; Ruiz-Canela, Miguel; Hu, Frank B.; Clish, Clary B.; Corella, Dolores; Salas-Salvadó, Jordi; Hruby, Adela; Fitó Colomer, Montserrat; Liang, Liming; Toledo, Estefania; Ros, Emilio; Estruch, Ramón; Gómez-Gracia, Enrique; Lapetra, José; Arós, Fernando; Romaguera Bosch, Dora; Serra-Majem, Luis; Guasch Ferré, Marta; Wang, Dong D.; Martínez-González, Miguel Ángel, 1957- (Oxford University Press, 2017)
    CONTEXT: Arginine, its methylated metabolites, and other metabolites related to the urea cycle have been independently associated with cardiovascular risk, but the potential causal meaning of these associations (positive ...
  • Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study
    Guasch Ferré, Marta; Hu, Frank B.; Ruiz-Canela, Miguel; Bulló, Mònica; Toledo, Estefania; Wang, Dong D.; Corella, Dolores; Gómez Gracia, Enrique; Fiol, Miquel; Estruch, Ramón; Lapetra, José; Fitó Colomer, Montserrat; Arós, Fernando; Serra-Majem, Luis; Ros, Emilio; Dennis, Courtney; Liang, Liming; Clish, Clary B.; Martínez-González, Miguel Ángel, 1957-; Salas-Salvadó, Jordi (Wiley, 2017)
    BACKGROUND: The relationship between plasma concentrations of betaine and choline metabolism and major cardiovascular disease (CVD) end points remains unclear. We have evaluated the association between metabolites from the ...
  • Urinary metabolomics of phenolic compounds reveals biomarkers of type-2 diabetes within the PREDIMED trial
    Domínguez-López, Inés; Lozano-Castellón, Julián; Vallverdú-Queralt, Anna; Jáuregui, Olga; Martínez-González, Miguel Ángel, 1957-; Hu, Frank B.; Fitó Colomer, Montserrat; Ros, Emilio; Estruch, Ramón; Lamuela-Raventós, Rosa M. (Elsevier, 2023)
    Background: Phenolic compounds have been associated with protective effects against type-2 diabetes (T2D). We used a metabolomics approach to determine urinary phenolic metabolites associated with T2D and fasting plasma ...

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