Browsing by Author "Hitte, Christophe"

Sort by: Order: Results:

  • A Point Mutation in a lincRNA Upstream of GDNF Is Associated to a Canine Insensitivity to Pain: A Spontaneous Model for Human Sensory Neuropathies
    Plassais, Jocelyn; Lagoutte, Laetitia; Correard, Solenne; Paradis, Manon; Guaguère, Eric; Hédan, Benoit; Pommier, Alix; Botherel, Nadine; Cadiergues, Marie-Christine; Pilorge, Philippe; Silversides, David; Bizot, Maud; Amuels, Mark; Arnan Ros, Carme; Johnson, Rory; Hitte, Christophe; Salbert, Gilles; Méreau, Agnès; Quignon, Pascale; Derrien, Thomas; André, Catherine (Public Library of Science (PLoS), 2016)
    Human Hereditary Sensory Autonomic Neuropathies (HSANs) are characterized by insensitivity to pain, sometimes combined with self-mutilation. Strikingly, several sporting dog breeds are particularly affected by such ...
  • Dog10K: an international sequencing effort to advance studies of canine domestication, phenotypes and health
    Ostrander, Elaine A.; Wang, Guo-Dong; Larson, Greger; vonHoldt, Bridgett M.; Davis, Brian W.; Jagannathan, Vidhya; Hitte, Christophe; Wayne, Robert K.; Zhang, Ya-Ping; Dog10K Consortium (Oxford University Press, 2019)
    Dogs are the most phenotypically diverse mammalian species, and they possess more known heritable disorders than any other non-human mammal. Efforts to catalog and characterize genetic variation across well-chosen populations ...
  • Genome-wide analysis of long non-coding RNA profiles in canine oral melanomas
    Hitte, Christophe; Le Béguec, Céline; Cadieu, Edouard; Wucher, Valentin; Primot, Aline; Prouteau, Anaïs; Botherel, Nadine; Hédan, Benoit; Lindblad-Toh, Kerstin; André, Catherine; Derrien, Thomas (MDPI, 2019)
    Mucosal melanomas (MM) are rare aggressive cancers in humans, and one of the most common forms of oral cancers in dogs. Similar biological and histological features are shared between MM in both species, making dogs a ...