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Browsing by Author "Gutiérrez Gallego, Ricardo, 1968-"

Browsing by Author "Gutiérrez Gallego, Ricardo, 1968-"

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  • Dissecting the energy metabolism in Mycoplasma pneumoniae through genome-scale metabolic modeling
    Wodke, Judith A.H.; Puchalka, Jacek; Lluch-Senar, Maria 1982-; Marcos del Águila, Josep, 1971-; Yus, Eva; Godinho, Miguel; Gutiérrez Gallego, Ricardo, 1968-; Martins dos Santos, Vitor; Serrano Pubull, Luis, 1982-; Klipp, E., 1965-; Maier, Tobias (Nature Publishing Group, 2013)
    Mycoplasma pneumoniae, a threatening pathogen with a minimal genome, is a model organism for bacterial systems biology for which substantial experimental information is available. With the goal of understanding the complex ...
  • Identification of antithrombin-modulating genes. Role of LARGE, a gene encoding a bifunctional
    de la Morena-Barrio, María Eugenia; Buil, Alfonso; Antón, Ana Isabel; Martínez-Martínez, Irene; Miñano, Antornia; Gutiérrez Gallego, Ricardo, 1968-; Navarro-Fernández, José; Águila, Sonia; Souto, Juan Carlos; Vicente, Vicente; Soria, José Manuel; Corral, Javier (Public Library of Science (PLoS), 2013)
    The haemostatic relevance of antithrombin together with the low genetic variability of SERPINC1, and the high heritability of plasma levels encourage the search for modulating genes. We used a hypothesis-free approach to ...
  • Identification of bovine sperm surface proteins involved in carbohydrate-mediated fertilization interactions
    Defaus, Sira; Avilés, Manuel; Andreu Martínez, David; Gutiérrez Gallego, Ricardo, 1968- (Elsevier, 2016)
    Glycan-protein interactions play a key role in mammalian fertilization, but data on the composition and identities of protein complexes involved in fertilization events are scarce, with the added complication that the ...
  • Increased N-glycosylation efficiency by generation of an aromatic sequon on N135 of antithrombin
    Águila, Sonia; Martínez-Martínez, Irene; Dichiara, Gilda; Gutiérrez Gallego, Ricardo, 1968-; Navarro-Fernández, José; Vicente, Vicente; Corral, Javier (Public Library of Science (PLoS), 2014)
    The inefficient glycosylation of consensus sequence on N135 in antithrombin explains the two glycoforms of this key anticoagulant serpin found in plasma: α and β, with four and three N-glycans, respectively. The lack of ...
  • Lectin-binding specificity of the fertilization-relevant protein PDC-109 by means of surface plasmon resonance and carbohydrate recognition domain excision-mass spectrometry
    Defaus, Sira; Avilés, Manuel; Andreu Martínez, David; Gutiérrez Gallego, Ricardo, 1968- (MDPI, 2018)
    Seminal plasma proteins are relevant for sperm functionality and some appear responsible for establishing sperm interactions with the various environments along the female genital tract towards the oocyte. In recent years, ...
  • Lysyl oxidase-like 2 deaminates lysine 4 in histone H3
    Herranz Martín, Nicolás; Dave, Natàlia; Millanes Romero, Alba, 1986-; Morey Ramonell, Lluís; Díaz, Víctor M.; Lórenz Fonfria, Víctor; Gutiérrez Gallego, Ricardo, 1968-; Jerónimo, Celia; Di Croce, Luciano; García de Herreros, Antonio; Peiró Sales, Sandra (American Society for Cell Biology, 2012)
    Methylation of lysine 4 (K4) within histone H3 has been linked to active transcription and is removed by LSD1 and the JmjC domain-containing proteins by amino-oxidation or hydroxylation, respectively. Here, we describe the ...
  • SUMOylation of the brain-predominant Ataxin-3 isoform modulates its interaction with p97
    Almeida Cotrim, Bruno; Abreu, Isabel A.; Matos, Carlos A.; Fraga, Joana F.; Fernandes, Sara; Macedo, Maria G.; Gutiérrez Gallego, Ricardo, 1968-; Barbosa Pereira, Pedro José; Carvalho, Ana Luísa; Macedo Ribeiro, Sandra (Elsevier, 2015)
    BACKGROUND: Machado-Joseph Disease (MJD), a form of dominantly inherited ataxia belonging to the group of polyQ expansion neurodegenerative disorders, occurs when a threshold value for the number of glutamines in Ataxin-3 ...

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