Browsing by Author "Gutiérrez Cuesta, Javier"

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  • Epigenetic and proteomic expression changes promoted by eating addictive-like behavior
    Mancino, Samantha, 1987-; Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Gutiérrez Martos, Miriam, 1989-; Martín García, Elena, 1975-; Pucci, Mariangela; Falconi, Anastasia; D'Addario, Claudio; Maccarrone, Mauro; Maldonado, Rafael, 1961- (Nature Publishing Group, 2015)
    An increasing perspective conceptualizes obesity and overeating as disorders related to addictive-like processes that could share common neurobiological mechanisms. In the present study, we aimed at validating an animal ...
  • Frustrated expected reward induces differential transcriptional changes in the mouse brain
    Martín García, Elena, 1975-; Fernández Castillo, Noelia; Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Sánchez-Mora, Cristina; Casas, Miguel; Ribasés, Marta; Cormand, Bru; Maldonado, Rafael, 1961- (Wiley, 2015)
    Frustration represents a particular aspect of the addictive process that is related to loss of control when the expected reward is not obtained. We aim to study the consequences of frustrated expected reward on gene ...
  • Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice
    Planagumà, Jesús; Leypoldt, Frank; Mannara, Francesco; Gutiérrez Cuesta, Javier; Martín García, Elena, 1975-; Aguilar, Esther; Titulaer, Maarten J.; Petit-Pedrol, Mar; Jain, Ankit; Balice-Gordon, Rita; Lakadamyali, Melike; Graus, Francesc; Maldonado, Rafael, 1961-; Dalmau, Josep (Oxford University Press, 2015)
    Anti-N-methyl D-aspartate receptor (NMDAR) encephalitis is a severe neuropsychiatric disorder that associates with prominent memory and behavioural deficits. Patients' antibodies react with the N-terminal domain of the ...
  • Intrathecal injection of P/Q type voltage-gated calcium channel antibodies from paraneoplastic cerebellar degeneration cause ataxia in mice
    Martín García, Elena, 1975-; Mannara, Francesco; Gutiérrez Cuesta, Javier; Sabater, Lidia; Dalmau, Josep; Maldonado, Rafael, 1961-; Graus, Francesc (Elsevier, 2013)
    The role of antibodies against the P/Q type voltage-gated calcium channels (VGCC-ab) in the pathogenesis of paraneoplastic cerebellar degeneration (PCD) and lung cancer is unclear. We evaluated in mice the effect of ...
  • Operant model of frustrated expected reward in mice
    Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Martín García, Elena, 1975-; Maldonado, Rafael, 1961- (Wiley-Blackwell, 2012)
    One aspect of the addictive process that has not been thoroughly investigated is the consequence of the frustrated state occurring when the drug is not available. The present study aimed to validate a novel operant model ...
  • The absence of VGLUT3 predisposes to cocaine abuse by increasing dopamine and glutamate signaling in the nucleus accumbens
    Sakae, Diana Yae; Martín García, Elena, 1975-; Gutiérrez Cuesta, Javier; Maldonado, Rafael, 1961-; El Mestikawy, Salah (Nature Publishing Group, 2015)
    Tonically active cholinergic interneurons (TANs) from the nucleus accumbens (NAc) are centrally involved in reward behavior. TANs express a vesicular glutamate transporter referred to as VGLUT3 and thus use both acetylcholine ...