Browsing by Author "Guerra Moreno, Ángel"

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  • AI-assisted proofreading of RNA splicing
    Guerra Moreno, Ángel; Valcárcel, J. (Juan) (Cold Spring Harbor Laboratory Press (CSHL Press), 2023)
    RNA helicases orchestrate proofreading mechanisms that facilitate accurate intron removal from pre-mRNAs. How these activities are recruited to spliceosome/pre-mRNA complexes remains poorly understood. In this issue of ...
  • Cross talk between the upstream exon-intron junction and Prp2 facilitates splicing of non-consensus introns
    Hümmer, Stefan; Borao Arriazu, Sonia, 1993-; Guerra Moreno, Ángel; Cozzuto, Luca; Hidalgo Hernando, Elena; Ayté del Olmo, José (Elsevier, 2021)
    Splicing of mRNA precursors is essential in the regulation of gene expression. U2AF65 recognizes the poly-pyrimidine tract and helps in the recognition of the branch point. Inactivation of fission yeast U2AF65 (Prp2) blocks ...
  • Prp4 kinase grants the license to splice: control of weak splice sites during spliceosome activation
    Eckert, Daniela; Andrée, Nicole; Razanau, Aleh; Zock-Emmenthal, Susanne; Lützelberger, Martin; Plath, Susann; Schmidt, Henning; Guerra Moreno, Ángel; Cozzuto, Luca; Ayté del Olmo, José; Käufer, Norbert F. (Public Library of Science (PLoS), 2016)
    The genome of the fission yeast Schizosaccharomyces pombe encodes 17 kinases that are essential for cell growth. These include the cell-cycle regulator Cdc2, as well as several kinases that coordinate cell growth, polarity, ...

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