Browsing by Author "Guerra, Stefano"

Sort by: Order: Results:

  • B Cell-Adaptive immune profile in emphysema-predominant chronic obstructive pulmonary disease
    Sullivan, John-Lawrence; Bagevalu, Bhavani; Glass, Carolyn; Sholl, Lynette; Kraft, Monica; Martinez, Fernando D.; Bastarrika, Gorka; de-Torres, Juan P.; Estepar, Raul San Jose; Guerra, Stefano; Polverino, Francesca (American Thoracic Society, 2019)
  • Characterisation and prognosis of undiagnosed chronic obstructive pulmonary disease patients at their first hospitalisation
    Balcells Vilarnau, Eva, 1967-; Gimeno Santos, Elena, 1980-; De Batlle, Jordi; Ramon, Maria Antonia; Rodríguez, Esther; Benet, Marta; Ferrer, Jaume; Farrero, Eva; Ferrer, Antoni-Lluc, 1942-; Guerra, Stefano; Ferrer, Jaume; Sauleda Roig, Jaume; Barberà, Joan Albert; Agustí, Alvar; Rodriguez, Robert, 1968-; Gea Guiral, Joaquim; Antó i Boqué, Josep Maria; García Aymerich, Judith (BioMed Central, 2015)
    Background. Under-diagnosis of COPD is an important unmet medical need. We investigated the characteristics and prognosis of hospitalised patients with undiagnosed COPD./nMethods. The PAC-COPD cohort included 342 COPD ...
  • Computational analysis of multimorbidity between asthma, eczema and rhinitis
    Aguilar, Daniel; Pinart, Mariona; Benet, Marta; García Aymerich, Judith; González Ruiz, Juan Ramón; Guerra, Stefano; Kogevinas, Manolis; Sunyer Deu, Jordi; Valverde, Sergi; Oliva Miguel, Baldomero; Antó i Boqué, Josep Maria (Public Library of Science (PLoS), 2017)
    Background: The mechanisms explaining the co-existence of asthma, eczema and rhinitis (allergic multimorbidity) are largely unknown. We investigated the mechanisms underlying multimorbidity between three main allergic ...
  • DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
    Joubert, Bonnie R.; Salas Díaz, Lucas Andrés, 1980-; Ruiz, Carlos; Bustamante Pineda, Mariona; Gonzalez, Juan Ramon; Pinart, Mariona; Guerra, Stefano; Vrijheid, Martine; Antó i Boqué, Josep Maria; Sunyer Deu, Jordi; London, Stephanie J. (Elsevier, 2016)
    Epigenetic modifications, including DNA methylation, represent a potential mechanism for environmental impacts on human disease. Maternal smoking in pregnancy remains an important public health problem that impacts child ...
  • Genetic and epigenetic regulation of YKL-40 in childhood
    Guerra, Stefano; Sunyer Deu, Jordi; Lavi, Iris; Benet, Marta; Bustamante Pineda, Mariona; Carsin, Anne-Elie; Dobaño, Carlota; Guxens Junyent, Mònica; Tischer, Christina; Vrijheid, Martine; Antó i Boqué, Josep Maria; Koppelman, Gerard H. (Elsevier, 2018)
    Background: Circulating levels of the chitinase-like protein YKL-40 are influenced by genetic variation in its encoding gene (chitinase 3–like 1 [CHI3L1]) and are increased in patients with several diseases, including ...
  • Inspiratory capacity-to-total lung capacity ratio and dyspnoea predict exercise capacity decline in COPD
    Ramon, Maria Antonia; Ferrer, Jaume; Gimeno Santos, Elena, 1980-; Donaire González, David; Rodríguez, Esther; Balcells Vilarnau, Eva, 1967-; De Batlle, Jordi; Benet, Marta; Guerra, Stefano; Sauleda Roig, Jaume; Ferrer, Antoni-Lluc, 1942-; Farrero, Eva; Gea Guiral, Joaquim; Barberà, Joan Albert; Agustí, Alvar; Rodríguez Roisin, Robert; Antó i Boqué, Josep Maria; García Aymerich, Judith; PAC-COPD Study Group (Wiley, 2016)
    BACKGROUND AND OBJECTIVE: Exercise capacity decline is a predictor of mortality in patients with chronic obstructive pulmonary disease (COPD). Static pulmonary hyperinflation is a key determinant of exercise performance, ...
  • Predictors of microbial agents in dust and respiratory health in the Ecrhs.
    Tischer, Christina; Zock, Jan-Paul; Valkonen, Maria; Doekes, Gert; Guerra, Stefano; Heederik, Dick; Jarvis, Deborah; Norbäck, Dan; Olivieri, Mario; Sunyer Deu, Jordi; Svanes, Cecilie; Täubel, Martin; Thiering, Elisabeth; Verlato, Giuseppe; Hyvärinen, Anne; Heinrich, Joachim (BioMed Central, 2015)
    BACKGROUND: Dampness and mould exposure have been repeatedly associated with respiratory health. However, less is known about the specific agents provoking or arresting health effects in adult populations. We aimed to ...
  • Regular physical activity levels and incidence of restrictive spirometry pattern: a longitudinal analysis of 2 population-based cohorts
    Carsin, Anne-Elie; Guerra, Stefano; García Aymerich, Judith (Oxford University Press, 2020)
    We estimated the association between regular physical activity and the incidence of restrictive spirometry pattern. Forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and physical activity were ...
  • Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a prospective study
    Guerra, Stefano; Halonen, Marilyn; Vasquez, Monica M.; Spangenberg, Amber; Stern, Debra A.; Morgan, Wayne J.; Wright, Anne L.; Carsin, Anne-Elie; Dobaño, Carlota; Barreiro Portela, Esther; Zock, Jan-Paul; Martínez-Moratalla, Jesús; Sunyer Deu, Jordi; Antó i Boqué, Josep Maria; Martinez, Fernando D. (Elsevier, 2015)
    BACKGROUND: Low concentrations of the anti-inflammatory protein CC16 (approved symbol SCGB1A1) in serum have been associated with accelerated decline in forced expiratory volume in 1 s (FEV1) in patients with chronic ...
  • Restrictive spirometry pattern is associated with low physical activity levels. A population based international study
    Carsin, Anne-Elie; Fuertes, Elaine; Antó i Boqué, Josep Maria; Guerra, Stefano; García Aymerich, Judith (Elsevier, 2019)
    Introduction: Restrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortality prognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and with ...
  • Serum cytokine profiles as predictors of asthma control in adults from the EGEA study
    Akiki, Zeina; Rava, Marta; Díaz Gil, Oscar; Pin, Isabelle; Moual, Nicole Le; Siroux, Valérie; Guerra, Stefano; Chamat, Soulaima; Matran, Regis; Fitó Colomer, Montserrat; Salameh, Pascale; Nadif, Rachel (Elsevier, 2017)
    BACKGROUND: To which extent serum cytokines may predict asthma control in adults remains understudied. OBJECTIVES: We investigated cross-sectional and longitudinal associations between cytokine profiles and asthma outcomes. ...
  • Systematic review protocol to define classical IgE-associated diseases from birth to adolescence: the MeDALL study
    Pinart, Mariona; Gimeno Santos, Elena, 1980-; García Aymerich, Judith; Guerra, Stefano; Benet, Marta; Jacquemin Leonard, Bénédicte; Kogevinas, Manolis; Lavi, Iris; Sunyer Deu, Jordi; Antó i Boqué, Josep Maria (WebmedCentral, 2012)
    BACKGROUND: Classical disease phenotypes are mainly based on descriptions of symptoms and the hypothesis that a given pattern of symptoms provides a diagnosis. With refined technologies there is growing evidence that disease ...
  • The role of C-reactive protein levels on the association of physical activity with lung function in adults
    Fuertes, Elaine; Carsin, Anne-Elie; Garcia-Larsen, Vanessa; Guerra, Stefano; Pin, Isabelle; Leynaert, Bénédicte; Accordini, Simone; Martínez-Moratalla, Jesús; Antó i Boqué, Josep Maria; Urrutia, Isabel; Le Gouellec, Audrey; Heinrich, Joachim; Gislason, Thorarinn; Jõgi, Rain; Janson, Christer; Jarvis, Debbie; García Aymerich, Judith (Public Library of Science (PLoS), 2019)
    Objective: Regular physical activity may be associated with improved lung function via reduced systemic inflammation, although studies exploring this mechanism are rare. We evaluated the role of C-reactive protein in blood, ...
  • Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS)
    Castro Giner, Francesc; Künzli, Nino; Jacquemin Leonard, Bénédicte; Forsberg, Bertil; Cid Ibeas, Rafael de; Sunyer Deu, Jordi; Jarvis, Deborah; Briggs, David; Vienneau, Danielle; Norbäck, Dan; Gonzalez, Juan Ramon; Guerra, Stefano; Janson, Christer; Antó i Boqué, Josep Maria; Wjst, Matthias; Heinrich, Joachim; Estivill, Xavier, 1955-; Kogevinas, Manolis (National Institute of Environmental Health Sciences (NIEHS), 2009)
    BACKGROUND: Traffic-related air pollution is related with asthma, and this association may be modified by genetic factors. OBJECTIVES: We investigated the role of genetic polymorphisms potentially modifying the association ...
  • Understanding allergic multimorbidity within the non-eosinophilic interactome
    Aguilar, Daniel; Lemonnier, Nathanael; Koppelman, Gerard H.; Melén, Erik; Oliva Miguel, Baldomero; Pinart, Mariona; Guerra, Stefano; Bousquet, Jean; Antó i Boqué, Josep Maria (Public Library of Science (PLoS), 2019)
    Background: The mechanisms explaining multimorbidity between asthma, dermatitis and rhinitis (allergic multimorbidity) are not well known. We investigated these mechanisms and their specificity in distinct cell types by ...