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Browsing by Author "Grebennikov, Dmitry"
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Browsing by Author "Grebennikov, Dmitry"
Now showing items 1-9 of 9
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Bocharov, Gennady A.; Grebennikov, Dmitry; Argilaguet Marqués, Jordi, 1977-; Meyerhans, Andreas (Elsevier, 2021)A fundamental unsolved issue in vaccine design is how neutralizing antibodies and cytotoxic CD8+ T cells cooperate numerically in controlling virus infections. We hypothesize on a viewpoint for the multiplicative cooperativity ...
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Bocharov, Gennady A.; Grebennikov, Dmitry; Cebollada Rica, Paula; Domenjó Vila, Eva, 1993-; Casella, Valentina, 1991-; Meyerhans, Andreas (Frontiers, 2022)The clinical handling of chronic virus infections remains a challenge. Here we describe recent progress in the understanding of virus - host interaction dynamics. Based on the systems biology concept of multi-stability and ...
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Grebennikov, Dmitry; Kholodareva, Ekaterina; Sazonov, Igor; Karsonova, Antonina; Meyerhans, Andreas; Bocharov, Gennady A. (MDPI, 2021)SARS-CoV-2 infection represents a global threat to human health. Various approaches were employed to reveal the pathogenetic mechanisms of COVID-19. Mathematical and computational modelling is a powerful tool to describe ...
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Sazonov, Igor; Grebennikov, Dmitry; Meyerhans, Andreas; Bocharov, Gennady A. (MDPI, 2021)Replication of Human Immunodeficiency Virus type 1 (HIV) in infected CD4+ T cells represents a key driver of HIV infection. The HIV life cycle is characterised by the heterogeneity of infected cells with respect to ...
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Modeling of the HIV-1 life cycle in productively infected cells to predict novel therapeutic targetsShcherbatova, Olga; Grebennikov, Dmitry; Sazonov, Igor; Meyerhans, Andreas; Bocharov, Gennady A. (MDPI, 2020)There are many studies that model the within-host population dynamics of Human Immunodeficiency Virus Type 1 (HIV-1) infection. However, the within-infected-cell replication of HIV-1 remains to be not comprehensively ...
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Bocharov, Gennady A.; Casella, Valentina, 1991-; Argilaguet Marqués, Jordi, 1977-; Grebennikov, Dmitry; Güerri Fernández, Roberto; Ludewig, Burkhard; Meyerhans, Andreas (Frontiers, 2020)
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Grebennikov, Dmitry; Karsonova, Antonina; Loguinova, Marina; Casella, Valentina, 1991-; Meyerhans, Andreas; Bocharov, Gennady A. (MDPI, 2022)A calibrated mathematical model of antiviral immune response to SARS-CoV-2 infection is developed. The model considers the innate and antigen-specific responses to SARS-CoV-2 infection. Recently published data sets from ...
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Sazonov, Igor; Grebennikov, Dmitry; Meyerhans, Andreas; Bocharov, Gennady A. (MDPI, 2022)Mathematical modelling of infection processes in cells is of fundamental interest. It helps to understand the SARS-CoV-2 dynamics in detail and can be useful to define the vulnerability steps targeted by antiviral treatments. ...
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Grebennikov, Dmitry; Bouchnita, Anass; Volpert, Vitaly; Bessonov, Nickolay; Meyerhans, Andreas; Bocharov, Gennady A. (Frontiers, 2019)The surveillance of host body tissues by immune cells is central for mediating their defense function. In vivo imaging technologies have been used to quantitatively characterize target cell scanning and migration of ...
Now showing items 1-9 of 9
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