Browsing by Author "García-Foncillas, Jesús"

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  • Calleja, Miguel Angel; Albanell Mestres, Joan; Aranda, Enrique; García-Foncillas, Jesús; Feliu, Anna; Rivera, Fernando; Oyagüez, Itziar; Salinas-Ortega, Laura; Soto Alvarez, Javier (BMJ Publishing Group, 2021)
    Objective: to assess the economic impact of introducing biosimilars of bevacizumab for the management of cancer patients receiving systemic bevacizumab in the National Health System (SNHS) of Spain. Methods: a 3-year budget ...
  • Luque, Melani; Cristóbal, Ion; Sanz Álvarez, Marta; Santos, Andrea; Zazo, Sandra; Eroles, Pilar; Arpí Llucià, Oriol; Rovira Guerín, Ana; Albanell Mestres, Joan; Madoz-Gúrpide, Juan; García-Foncillas, Jesús; Rojo, Federico (MDPI, 2022)
    Together with its reported ability to modulate AKT phosphorylation (p-AKT) status in several tumor types, the oncoprotein CIP2A has been described to induce breast cancer progression and drug resistance. However, the ...
  • Sanz Álvarez, Marta; Cristóbal, Ion; Luque, Melani; Santos, Andrea; Zazo, Sandra; Madoz-Gúrpide, Juan; Caramés, Cristina; Chiang, Cheng-Ming; García-Foncillas, Jesús; Eroles, Pilar; Albanell Mestres, Joan; Rojo, Federico (MDPI, 2021)
    The bromodomain-containing protein 4 (BRD4), a member of the bromodomain and extra-terminal domain (BET) protein family, has emerged in the last years as a promising molecular target in many tumors including breast cancer. ...
  • Rincón, Raúl; Cristóbal, Ion; Zazo, Sandra; Arpí Llucià, Oriol; Menendez Romero, Silvia; Manso, Rebeca; Lluch, Ana; Eroles, Pilar; Rovira Guerín, Ana; Albanell Mestres, Joan; García-Foncillas, Jesús; Madoz-Gúrpide, Juan; Rojo, Federico (Impact Journals, 2015)
    The protein phosphatase 2A (PP2A) is a key tumor suppressor which has emerged as a novel molecular target in some human cancers. Here, we show that PP2A inhibition is a common event in breast cancer and identified PP2A ...
  • García-Foncillas, Jesús; Tabernero Cartula, Josep; Élez, Elena; Aranda, Enrique; Benavides, Manuel; Camps, Carlos; Jantus-Lewintre, Eloisa; López, Rafael; Muinelo-Romay, Laura; Montagut Viladot, Clara; Antón, Antonio; López, Guillermo; Díaz-Rubio, Eduardo; Rojo, Federico; Vivancos Prellezo, Ana (Nature Research, 2018)
    BACKGROUND: Liquid biopsy offers a minimally invasive alternative to tissue-based evaluation of mutational status in cancer. The goal of the present study was to evaluate the aggregate performance of OncoBEAM RAS mutation ...
  • Martínez-Useros, Javier; Georgiev Hristov, Tihomir; Fernández Aceñero, María Jesús; Borrero-Palacios, Aurea; Indacochea Cusirramos, Alberto; Guerrero Jijon, Santiago Xavier; Li, Weiyao; Cebrián, Arancha; del Pulgar, Teresa Gómez; Puime Otín, Alberto; Puerto Nevado, Laura del; Rodríguez Remírez, María; Pérez, Núria; Celdrán Uriarte, Ángel; Gebauer, Fátima; García-Foncillas, Jesús (Public Library of Science (PLoS), 2017)
    Pancreatic ductal adenocarcinoma is an aggressive form of pancreatic cancer and the fourth leading cause of cancer-related death. When possible, curative approaches are based on surgical resection, though not every patient ...
  • Prieto-Potin, Iván; Carvajal, Nerea; Plaza-Sánchez, Jenifer; Manso, Rebeca; Aúz-Alexandre, Carmen Laura; Chamizo, Cristina; Zazo, Sandra; López-Sánchez, Almudena; Rodríguez-Pinilla, Socorro María; Camacho Díaz, Laura; Longarón Rozalen, Raquel; Bellosillo Paricio, Beatriz; Somoza, Rosa; Hernández-Losa, Javier; Fernández-Soria, Víctor Manuel; Ramos-Ruiz, Ricardo; Cristóbal, Ion; García-Foncillas, Jesús; Rojo, Federico (PeerJ Inc., 2020)
    Background: Next-generation sequencing (NGS) is a high-throughput technology that has become widely integrated in molecular diagnostics laboratories. Among the large diversity of NGS-based panels, the Trusight Tumor 26 ...

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