Visualitza per autoria "Gabaldón Estevan, Juan Antonio, 1973-"

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  • A metabolic scenario for the evolutionary origin of peroxisomes from the endomembranous system
    Gabaldón Estevan, Juan Antonio, 1973- (SpringerOpen, 2014)
    A novel model for the evolutionary origin of peroxisomes and related organelles from within the endoplasmic reticulum is proposed.
  • A mouse model suggests that heart failure and its common comorbidity sleep fragmentation have no synergistic impacts on the gut microbiome
    Khannous Lleiffe, Olfat; Willis, Jesse R.; Saus Martínez, Ester; Cabrera-Aguilera, Ignacio; Almendros, Isaac; Farré, Ramon; Gozal, David; Farré López, Núria; Gabaldón Estevan, Juan Antonio, 1973- (MDPI, 2021)
    Heart failure (HF) is a common condition associated with a high rate of hospitalizations and adverse outcomes. HF is characterized by impairments of either the cardiac ventricular filling, ejection of blood capacity or ...
  • A phylogenomics approach for selecting robust sets of phylogenetic markers
    Capella Gutiérrez, Salvador Jesús, 1985-; Kauff, Frank; Gabaldón Estevan, Juan Antonio, 1973- (Oxford University Press, 2014)
    Reconstructing the evolutionary relationships of species is a major goal in biology. Despite the increasing number of completely sequenced genomes, a large number of phylogenetic projects rely on targeted sequencing and ...
  • Adaptation of S. cerevisiae to fermented food environments reveals remarkable genome plasticity and the footprints of domestication
    Legras, Jean-Luc; Galeote, Virginie; Bigey, Frédéric; Camarasa, Carole; Marsit, Souhir; Nidelet, Thibault; Sanchez, Isabelle; Couloux, Arnaud; Guy, Julie; Franco-Duarte, Ricardo; Marcet Houben, Marina; Gabaldón Estevan, Juan Antonio, 1973-; Schuller, Dorit; Sampaio, José Paulo; Dequin, Sylvie (Oxford University Press, 2018)
    The budding yeast Saccharomyces cerevisiae can be found in the wild and is also frequently associated with human activities. Despite recent insights into the phylogeny of this species, much is still unknown about how ...
  • Advances and applications in the quest for orthologs
    Glover, Natasha; Dessimoz, Christophe; Ebersberger, Ingo; Forslund, Sofia K.; Gabaldón Estevan, Juan Antonio, 1973-; Huerta Cepas, Jaime; Martin, Maria-Jesus; Muffato, Matthieu; Patricio, Mateus; Pereira, Cecile; Sousa da Silva, Alan; Wang, Yan-Dong; Sonnhammer, Erik; Thomas, Paul D. (Oxford University Press, 2019)
    Gene families evolve by the processes of speciation (creating orthologs), gene duplication (paralogs), and horizontal gene transfer (xenologs), in addition to sequence divergence and gene loss. Orthologs in particular play ...
  • An expanded evaluation of protein function prediction methods shows an improvement in accuracy
    Jiang, Yuxiang; Gabaldón Estevan, Juan Antonio, 1973-; Marcet Houben, Marina; Supek, Fran; Radivojac, Predrag (BioMed Central, 2016)
    Background: A major bottleneck in our understanding of the molecular underpinnings of life is the assignment of function to proteins. While molecular experiments provide the most reliable annotation of proteins, their ...
  • Ancient dispersal of the human fungal pathogen Cryptococcus gattii from the Amazon rainforest
    Hagen, Ferry; Ceresini, Paulo C.; Polacheck, Itzhack; Ma, Hansong; Nieuwerburgh, Filip van; Gabaldón Estevan, Juan Antonio, 1973-; Kagan, Sarah; Pursall, E. Rhiannon; Hoogveld, Hans L.; Iersel, Leo J. van; Klau, Gunnar W.; Kelk, Steven M.; Stougie, Leen; Bartlett, Karen H.; Voelz, Kerstin; Pryszcz, Leszek Piotr, 1985-; Castañeda, Elizabeth; Lazera, Marcia; Meyer, Wieland; Deforce, Dieter; Meis, Jacques F.; May, Robin C.; Klaassen, Corné H. W.; Boekhout, Teun (Public Library of Science (PLoS), 2013)
    Over the past two decades, several fungal outbreaks have occurred, including the high-profile 'Vancouver Island' and 'Pacific Northwest' outbreaks, caused by Cryptococcus gattii, which has affected hundreds of otherwise ...
  • Apolipoprotein L2 contains a BH3-like domain but it does not behave as a BH3-only protein
    Galindo-Moreno, Juan; Iurlaro, Raffaella; El Mjiyad, Nadia; Díez-Pérez, Javier; Gabaldón Estevan, Juan Antonio, 1973-; Muñoz-Pinedo, Cristina (Springer, 2014)
    Apolipoproteins of the L family are lipid-binding proteins whose function is largely unknown. Apolipoprotein L1 and apolipoprotein L6 have been recently described as novel pro-death BH3-only proteins that are also capable ...
  • ArthropodaCyc: a CycADS powered collection of BioCyc databases to analyse and compare metabolism of arthropods
    Baa-Puyoulet, Patrice; Parisot, Nicolas; Febvay, Gérard; Huerta Cepas, Jaime; Vellozo, Augusto F.; Gabaldón Estevan, Juan Antonio, 1973-; Calevro, Federica; Charles, Hubert; Colella, Stefano (Oxford University Press, 2016)
    Arthropods interact with humans at different levels with highly beneficial roles (e.g. as pollinators), as well as with a negative impact for example as vectors of human or animal diseases, or as agricultural pests. Several ...
  • Bacillus firmus strain I-1582, a nematode antagonist by itself and through the plant
    Ghahremani, Zahra; Escudero, Nuria; Beltrán Anadón, Daniel; Saus Martínez, Ester; Cunquero, Marina; Andilla, Jordi; Loza-Alvarez, Pablo; Gabaldón Estevan, Juan Antonio, 1973-; Sorribas, F. Javier (Frontiers, 2020)
    Bacillus firmus I-1582 is approved in Europe for the management of Meloidogyne on vegetable crops. However, little information about its modes of action and temperature requirements is available, despite the effect of these ...
  • Beyond the whole-genome duplication: phylogenetic evidence for an ancient interspecies hybridization in the Baker's yeast lineage
    Marcet Houben, Marina; Gabaldón Estevan, Juan Antonio, 1973- (Public Library of Science (PLoS), 2015)
    Whole-genome duplications have shaped the genomes of several vertebrate, plant, and fungal lineages. Earlier studies have focused on establishing when these events occurred and on elucidating their functional and evolutionary ...
  • Biological processes modulating longevity across primates: a phylogenetic genome-phenome analysis
    Muntané, Gerard; Farré, Xavier; Rodríguez Pérez, Juan Antonio, 1985-; Pegueroles Queralt, Maria Cinta; Hughes, David; Magalhães, João Pedro de; Gabaldón Estevan, Juan Antonio, 1973-; Navarro i Cuartiellas, Arcadi, 1969- (Oxford University Press, 2018)
    Aging is a complex process affecting different species and individuals in different ways. Comparing genetic variation across species with their aging phenotypes will help understanding the molecular basis of aging and ...
  • Candida pathogens induce protective mitochondria-associated type I interferon signalling and a damage-driven response in vaginal epithelial cells
    Pekmezovic, Marina; Hovhannisyan, Hrant, 1992-; Gresnigt, Mark S.; Iracane, Elise; Oliveira Pacheco, João; Siscar Lewin, Sofía; Seemann, Eric; Qualmann, Britta; Kalkreuter, Till; Müller, Sylvia; Kamradt, Thomas; Mogavero, Selene; Brunke, Sascha; Butler, Geraldine; Gabaldón Estevan, Juan Antonio, 1973-; Hube, Bernhard (Nature Research, 2021)
    Vaginal candidiasis is an extremely common disease predominantly caused by four phylogenetically diverse species: Candida albicans; Candida glabrata; Candida parapsilosis; and Candida tropicalis. Using a time course infection ...
  • Changes in the stool and oropharyngeal microbiome in obsessive-compulsive disorder
    Domènech Salgado, Laura, 1989-; Willis, Jesse R.; Alemany-Navarro, María; Morell, Marta; Real, Eva; Escaramís, Geòrgia; Bertolín, Sara; Sánchez Chinchilla, Daniel; Balcells, Susana; Segalàs, Cinto; Estivill, Xavier, 1955-; Menchón, José M.; Gabaldón Estevan, Juan Antonio, 1973-; Alonso, Pino; Rabionet, Raquel (Nature Research, 2022)
    Although the etiology of obsessive-compulsive disorder (OCD) is largely unknown, it is accepted that OCD is a complex disorder. There is a known bi-directional interaction between the gut microbiome and brain activity. ...
  • Characterization of ecologically diverse viruses infecting co-occurring strains of cosmopolitan hyperhalophilic bacteroidetes
    Villamor, Judith; Ramos-Barbero, María Dolores; González-Torres, Pedro; Gabaldón Estevan, Juan Antonio, 1973-; Rosselló-Mora, Ramón; Meseguer, Inmaculada; Martínez García, Manuel; Santos, Fernando; Antón, Josefa (Nature Research, 2018)
    Hypersaline environments close to saturation harbor the highest density of virus-like particles reported for aquatic systems as well as low microbial diversity. Thus, they offer unique settings for studying virus-host ...
  • Chromosome-level assembly, annotation and phylome of Pelobates cultripes, the western spadefoot toad
    Liedtke, H. Christoph; Cruz, Fernando; Gómez Garrido, Jèssica; Fuentes Palacios, Diego; Marcet Houben, Marina; Gut, Marta; Alioto, Tyler; Gabaldón Estevan, Juan Antonio, 1973-; Gomez-Mestre, Ivan (Oxford University Press, 2022)
    Genomic resources for amphibians are still hugely under-represented in vertebrate genomic research, despite being a group of major interest for ecology, evolution and conservation. Amphibians constitute a highly threatened ...
  • Citizen science charts two major "stomatotypes" in the oral microbiome of adolescents and reveals links with habits and drinking water composition
    Willis, Jesse R.; González-Torres, Pedro; Pittis, Alexandros, 1982-; Bejarano, Luis A.; Cozzuto, Luca; Andreu Somavilla, Núria; Alloza-Trabado, Miriam; Valentín, Antònia; Ksiezopolska, Ewa; Company, Carlos; Onywera, Harris; Montfort, Magda; Hermoso Pulido, Antonio; Iraola Guzmán, Susana; Saus Martínez, Ester; Labeeuw, Annick; Carolis, Carlo; Hecht, Jochen; Ponomarenko, Julia; Gabaldón Estevan, Juan Antonio, 1973- (BioMed Central, 2018)
    Background: The oral cavity comprises a rich and diverse microbiome, which plays important roles in health and disease. Previous studies have mostly focused on adult populations or in very young children, whereas the ...
  • Citizen-science based study of the oral microbiome in Cystic fibrosis and matched controls reveals major differences in diversity and abundance of bacterial and fungal species
    Willis, Jesse R.; Saus Martínez, Ester; Iraola Guzmán, Susana; Cabello-Yeves, Elena; Ksiezopolska, Ewa; Cozzuto, Luca; Bejarano, Luis A.; Andreu Somavilla, Núria; Alloza-Trabado, Miriam; Blanco, Andrea; Puig-Sola, Anna; Broglio, Elisabetta; Carolis, Carlo; Ponomarenko, Julia; Hecht, Jochen; Gabaldón Estevan, Juan Antonio, 1973- (Taylor & Francis, 2021)
    Introduction: Cystic fibrosis (CF) is an autosomal genetic disease, associated with the production of excessively thick mucosa and with life-threatening chronic lung infections. The microbiota of the oral cavity can act ...
  • Citizen-science reveals changes in the oral microbiome in Spain through age and lifestyle factors
    Willis, Jesse R.; Saus Martínez, Ester; Iraola Guzmán, Susana; Ksiezopolska, Ewa; Cozzuto, Luca; Bejanaro, Luis A.; Andreu Somavilla, Núria; Alloza-Trabado, Miriam; Blanco, Andrea; Puig-Sola, Anna; Broglio, Elisabetta; Carolis, Carlo; Ponomarenko, Julia; Hecht, Jochen; Gabaldón Estevan, Juan Antonio, 1973- (Nature Research, 2022)
    The relevance of the human oral microbiome to our understanding of human health has grown in recent years as microbiome studies continue to develop. Given the links of the oral cavity with the digestive, respiratory and ...
  • Client applications and server-side docker for management of RNASeq and/or variantSeq workflows and pipelines of the GPRO Suite
    Hafez Khafaga, Ahmed Ibrahem, 1987-; Soriano, Beatriz; Elsayed, Aya Allah; Futami, Ricardo; Ceprian, Raquel; Ramos-Ruiz, Ricardo; Martinez, Genis; Roig, Francisco Jose; Torres-Font, Miguel Angel; Naya Català, Fernando; Calduch-Giner, Josep Alvar; Trilla Fuertes, Lucía; Gamez-Pozo, Angelo; Arnau, Vicente; Sempere-Luna, Jose Maria; Perez-Sanchez, Jaume; Gabaldón Estevan, Juan Antonio, 1973-; Llorens, Carlos, 1968- (MDPI, 2023)
    The GPRO suite is an in-progress bioinformatic project for -omics data analysis. As part of the continued growth of this project, we introduce a client- and server-side solution for comparative transcriptomics and analysis ...

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