Browsing by Author "Gómez-Gracia, Enrique"

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  • American Heart Association's life simple 7 and the risk of atrial fibrillation in the PREDIMED study cohort
    Díaz-Gutiérrez, Jesús; Martínez-González, Miguel Ángel, 1957-; Alonso, Alvaro; Toledo, Estefania; Salas Salvadó, Jordi; Sorlí, José Vicente; Ros, Emilio; Fitó Colomer, Montserrat; Estruch, Ramón; Arós, Fernando; Fiol, Miquel; Lapetra, José; Gómez-Gracia, Enrique; Serra Majem, Lluís; Pintó Sala, Xavier; Portolés, Olga; Babio, Nancy; Castañer, Olga; Ruiz-Canela, Miguel (Elsevier, 2023)
    Background and aims: The American Heart Association proposed 7 ideal cardiovascular health metrics (Life's Simple 7 [LS7]) namely, not smoking, body mass index <25 kg/m2, healthy diet, moderate physical activity ≥150 ...
  • Chromium Exposure and Risk of Cardiovascular Disease in High Cardiovascular Risk Subjects　- Nested Case-Control Study in the Prevention With Mediterranean Diet (PREDIMED) Study
    Gutiérrez Bedmar, Mario; Martínez-González, Miguel Ángel, 1957-; Muñoz-Bravo, Carlos; Ruiz-Canela, Miguel; Mariscal, Alberto; Salas Salvadó, Jordi; Estruch, Ramón; Corella, Dolores; Arós, Fernando; Fitó Colomer, Montserrat; Lapetra, José; Serra-Majem, Luis; Ros, Emilio; Alonso-Gómez, Ángel; Portolés, Olga; Fiol, Miquel; Bulló, Mònica; Castañer, Olga; Pinto, Xavier; Gómez-Gracia, Enrique ( The Japanese Circulation Society , 2017)
    BACKGROUND: Epidemiological data on chromium (Cr) exposure and the risk of cardiovascular disease (CVD) are still limited. Toenail Cr level (TCL) provides a time-integrated measure reflecting long-term Cr exposure. We ...
  • Circulating citric acid cycle metabolites and risk of cardiovascular disease in the PREDIMED study
    Santos-Lozano, José; Ruiz-Canela, Miguel; Razquin, Cristina; Clish, Clary B.; Guasch Ferré, Marta; Babio, Nancy; Corella, Dolores; Gómez-Gracia, Enrique; Fiol, Miquel; Estruch, Ramón; Lapetra, José; Fitó Colomer, Montserrat; Arós, Fernando; Serra-Majem, Luis; Liang, Liming; Martínez, María Ángeles; Toledo, Estefania; Salas Salvadó, Jordi; Hu, Frank B.; Martínez-González, Miguel Ángel, 1957- (Elsevier, 2023)
    Background and aim Plasma citric acid cycle (CAC) metabolites might be likely related to cardiovascular disease (CVD). However, studies assessing the longitudinal associations between circulating CAC-related metabolites ...
  • CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial.
    Corella, Dolores; Asensio, Eva María; Coltell, Oscar; Sorlí, José Vicente; Ramón, Estruch; Martínez-González, Miguel Ángel, 1957-; Salas-Salvadó, Jordi; Castañer, Olga; Arós, Fernando; Lapetra, José; Serra-Majem, Luis; Gómez-Gracia, Enrique; Ortega‑Azorín, Carolina; Fiol, Miquel; Díez Espino, Javier; Díaz‑López, Andrés; Fitó Colomer, Montserrat; Ros, Emilio; Ordovás, José M. (Springer Verlag, 2016)
    BACKGROUND: Circadian rhythms regulate key biological processes influencing metabolic pathways. Disregulation is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). Circadian rhythms are generated by ...
  • Consumption of iogurt, low-fat milk, and other low-fat dairy products is associated with lower risk of metabolic syndrome incidence in an elderly mediterranean population.
    Babio, Nancy; Becerra-Tomás, Nerea; Martínez-González, Miguel Ángel, 1957-; Corella, Dolores; Estruch, Ramón; Ros, Emilio; Sayón-Orea, Carmen; Fitó Colomer, Montserrat; Serra-Majem, Luis; Arós, Fernando; Lamuela-Raventós, Rosa M.; Lapetra, José; Gómez-Gracia, Enrique; Fiol, Miquel; Díaz‑López, Andrés; Sorlí, José Vicente; Martínez, José Alfredo; Salas-Salvadó, Jordi; PREDIMED investigators (American Society for Nutrition, 2015)
    BACKGROUND: The association between consumption of dairy products and the risk of developing metabolic syndrome (MetS) is unclear./nOBJECTIVE: The purpose of this study was to evaluate the associations between consumption ...
  • Dairy product consumption and risk of type 2 diabetes in an elderly Spanish Mediterranean population at high cardiovascular risk.
    Díaz‑López, Andrés; Bulló, Mònica; Martínez-González, Miguel Ángel, 1957-; Corella, Dolores; Estruch, Ramón; Fitó Colomer, Montserrat; Gómez-Gracia, Enrique; Fiol, Miquel; García de la Corte, Francisco Javier; Ros, Emilio; Babio, Nancy; Serra-Majem, Luis; Pinto, Xavier; Muñoz, Miguel Ángel; Francés, Francisco; Buil-Cosiales, Pilar; Salas-Salvadó, Jordi (Springer Verlag , 2016)
    PURPOSE The possible effects of dairy consumption on diabetes prevention remain controversial. The aim of this study was to investigate the association between the dairy consumption and type 2 diabetes (T2D) risk in an ...
  • Effects of a mediterranean eating plan on the need for glucose-lowering medications in participants with type 2 diabetes: a subgroup analysis of the PREDIMED trial
    Basterra-Gortari, F. Javier; Ruiz-Canela, Miguel; Martínez-González, Miguel Ángel, 1957-; Babio, Nancy; Sorlí, José Vicente; Fitó Colomer, Montserrat; Ros, Emilio; Gómez-Gracia, Enrique; Fiol, Miquel; Lapetra, José; Estruch, Ramón; Serra-Majem, Luis; Pinto, Xavier; González, José I.; Bulló, Mònica; Castañer, Olga; Alonso-Gómez, Ángel; Forga, Luis; Arós, Fernando; PREDIMED investigators (American Diabetes Association, 2019)
    OBJECTIVE: To examine the effects of two Mediterranean eating plans (Med-EatPlans) versus a low-fat eating plan on the need for glucose-lowering medications. RESEARCH DESIGN AND METHODS: From the Prevención con Dieta ...
  • Egg consumption and cardiovascular disease according to diabetic status: The PREDIMED study
    Díez-Espino, J.; Basterra-Gortari, F. Javier; Salas-Salvadó, Jordi; Buil-Cosiales, Pilar; Corella, Dolores; Schröder, Helmut, 1958-; Estruch, Ramón; Ros, Emilio; Gómez-Gracia, Enrique; Arós, Fernando; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Pintó Sala, Xavier; Babio, Nancy; Quiles, Laura; Fitó Colomer, Montserrat; Martí, Amelia; Toledo, Estefania; PREDIMED investigators (Elsevier, 2017)
    BACKGROUND: Eggs are a major source of dietary cholesterol and their consumption has been sometimes discouraged. A relationship between egg consumption and the incidence of cardiovascular disease (CVD) has been suggested ...
  • Mediterranean diet, energy restriction, physical activity, and atherogenicity of very-low density lipoproteins: Findings from two randomized controlled trials
    Pérez-Vega, Karla Alejandra; Castañer, Olga; Sanllorente Melenchón, Albert; Lassale, Camille; Ros, Emilio; Pintó Sala, Xavier; Estruch, Ramón; Salas Salvadó, Jordi; Corella, Dolores; Alonso-Gómez, Ángel; Serra-Majem, Luis; Razquin, Cristina; Fiol, Miquel; Lapetra, José; Gómez-Gracia, Enrique; Tinahones Madueño, Francisco José; Hernáez, Álvaro; Fitó Colomer, Montserrat (Wiley, 2023)
    Scope: Some very-low density lipoprotein (VLDL) properties may render them more pro-atherogenic. We aimed to assess whether a Mediterranean diet (MedDiet) or an energy-reduced MedDiet with increased physical activity ...
  • Mediterranean diet, retinopathy, nephropathy, and microvascular diabetes complications: a post hoc analysis of a randomized trial.
    Díaz‑López, Andrés; Babio, Nancy; Martínez-González, Miguel Ángel, 1957-; Dolores, Corella; Amor, Antonio J.; Fitó Colomer, Montserrat; Estruch, Ramón; Arós, Fernando; Gómez-Gracia, Enrique; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Basora, Josep; Basterra-Gortari, F. Javier; Zanon-Moreno, Vicente; Muñoz, Miguel Ángel; Salas-Salvadó, Jordi; PREDIMED investigators (American Diabetes Association, 2015)
    OBJECTIVE: To date no clinical trials have evaluated the role of dietary patterns on the incidence of microvascular diabetes complications. We hypothesized that a nutritional intervention based on the Mediterranean diet ...
  • Metabolites of glutamate metabolism are associated with incident cardiovascular events in the PREDIMED PREvención con DIeta MEDiterránea (PREDIMED) Trial.
    Zheng, Yan; Hu, Frank B.; Ruiz-Canela, Miguel; Clish, Clary B.; Dennis, Courtney; Salas-Salvadó, Jordi; Hruby, Adela; Liang, Liming; Toledo, Estefania; Corella, Dolores; Ros, Emilio; Fitó Colomer, Montserrat; Gómez-Gracia, Enrique; Arós, Fernando; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Estruch, Ramón; Martínez-González, Miguel Ángel, 1957- (Willey, 2016)
    BACKGROUND: Glutamate metabolism may play a role in the pathophysiology of cardiometabolic disorders. However, there is limited evidence of an association between glutamate-related metabolites and, moreover, changes in ...
  • Moderate red wine consumption is associated with a lower prevalence of the metabolic syndrome in the PREDIMED population.
    Tresserra-Rimbau, Anna; Medina-Remón, Alexander; Lamuela-Raventós, Rosa M.; Bulló, Mònica; Salas-Salvadó, Jordi; Corella, Dolores; Fitó Colomer, Montserrat; Gea, Alfredo; Gómez-Gracia, Enrique; Lapetra, José; Arós, Fernando; Fiol, Miquel; Ros, Emilio; Serra-Majem, Luis; Pinto, Xavier; Muñoz, Miguel Ángel; Estruch, Ramón; PREDIMED investigators (Cambridge University Press, 2015)
    Previous studies on the association between alcohol intake and the development of the metabolic syndrome (MetS) have yielded inconsistent results. Besides, few studies have analysed the effects of red wine (RW) consumption ...
  • One-year changes in urinary microbial phenolic metabolites and the risk of type 2 diabetes: a case-control study
    Marhuenda Muñoz, María; Domínguez-López, Inés; Laveriano-Santos, Emily P.; Parilli-Moser, Isabella; Razquin, Cristina; Ruiz-Canela, Miguel; Basterra-Gortari, F. Javier; Salas-Salvadó, Jordi; Fitó Colomer, Montserrat; Lapetra, José; Arós, Fernando; Fiol, Miquel; Serra-Majem, Luis; Pintó Sala, Xavier; Gómez-Gracia, Enrique; Ros, Emilio; Estruch, Ramón; Lamuela-Raventós, Rosa M. (MDPI, 2022)
    The intake of polyphenols has been associated with a risk reduction of type 2 diabetes. Nevertheless, to the best of our knowledge, the molecules that might be metabolically active after ingestion are only starting to be ...
  • Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study
    Yu, Edward; Ruiz-Canela, Miguel; Hu, Frank B.; Clish, Clary B.; Corella, Dolores; Salas-Salvadó, Jordi; Hruby, Adela; Fitó Colomer, Montserrat; Liang, Liming; Toledo, Estefania; Ros, Emilio; Estruch, Ramón; Gómez-Gracia, Enrique; Lapetra, José; Arós, Fernando; Romaguera Bosch, Dora; Serra-Majem, Luis; Guasch Ferré, Marta; Wang, Dong D.; Martínez-González, Miguel Ángel, 1957- (Oxford University Press, 2017)
    CONTEXT: Arginine, its methylated metabolites, and other metabolites related to the urea cycle have been independently associated with cardiovascular risk, but the potential causal meaning of these associations (positive ...
  • Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic Risk Scores
    Corella, Dolores; Coltell, Oscar; Sorlí, José Vicente; Estruch, Ramón; Quiles, Laura; Martínez-González, Miguel Ángel, 1957-; Salas Salvadó, Jordi; Castañer, Olga; Arós, Fernando; Ortega Calvo, Manuel; Serra Majem, Lluís; Gómez-Gracia, Enrique; Portolés, Olga; Fiol, Miquel; Díez Espino, Javier; Basora, Josep; Fitó Colomer, Montserrat; Ros, Emilio; Ordovás, José M. (MDPI Publishing, 2016)
    Nutrigenetic studies analyzing gene-diet interactions of the TCF7L2-rs7903146 C > T polymorphism on type-2 diabetes (T2D) have shown controversial results. A reason contributing to this may be the additional modulation by ...
  • Predictors of short- and long-term adherence with a Mediterranean-type diet intervention: the PREDIMED randomized trial.
    Downer, Mary Kathryn; Gea, Alfredo; Stampfer, Meir; Sánchez-Tainta, Ana; Corella, Dolores; Salas-Salvadó, Jordi; Ros, Emilio; Estruch, Ramón; Fitó Colomer, Montserrat; Gómez-Gracia, Enrique; Arós, Fernando; Fiol, Miquel; Garcia De-la-Corte, Francisco Jose; Serra-Majem, Luis; Pinto, Xavier; Basora, Josep; Sorlí, José Vicente; Vinyoles, Ernest; Zazpe, Itziar; Martínez-González, Miguel Ángel, 1957- (BioMed Central, 2016)
    BACKGROUND: Dietary intervention success requires strong participant adherence, but very few studies have examined factors related to both short-term and long-term adherence. A better understanding of predictors of adherence ...
  • Quality of dietary fat intake and body weight and obesity in a mediterranean population: secondary analyses within the PREDIMED trial
    Beulen, Yvette; Martínez-González, Miguel Ángel, 1957-; van de Rest, Ondine; Salas-Salvadó, Jordi; Sorlí, José Vicente; Gómez-Gracia, Enrique; Fiol, Miquel; Estruch, Ramón; Santos-Lozano, José; Schröder, Helmut, 1958-; Alonso-Gómez, Ángel; Serra-Majem, Luis; Pinto, Xavier; Ros, Emilio; Becerra-Tomás, Nerea; González, José I.; Fitó Colomer, Montserrat; Martínez, José Alfredo; Gea, Alfredo (MDPI, 2018)
    A moderately high-fat Mediterranean diet does not promote weight gain. This study aimed to investigate the association between dietary intake of specific types of fat and obesity and body weight. A prospective cohort study ...
  • Replacing red meat and processed red meat for white meat, fish, legumes or eggs is associated with lower risk of incidence of metabolic syndrome.
    Becerra-Tomás, Nerea; Babio, Nancy; Martínez-González, Miguel Ángel, 1957-; Corella, Dolores; Estruch, Ramón; Emilio, Ros; Fitó Colomer, Montserrat; Serra-Majem, Luis; Salaverria, Itziar; Lamuela-Raventós, Rosa M.; Lapetra, José; Gómez-Gracia, Enrique; Fiol, Miquel; Toledo, Estefania; Sorlí, José Vicente; Pedret-Llaberia, Maria Roser; Salas-Salvadó, Jordi (Elsevier, 2016)
    BACKGROUND & AIMS: Few studies have assessed the association between consumption of red meat (RM) and processed red meats (PRM) and the incidence of metabolic syndrome (MetS) and results have been inconsistent. We investigated ...
  • Serum selenium and incident cardiovascular disease in the PREvención con DIeta MEDiterránea (PREDIMED) trial: Nested case-control study
    Gutiérrez Bedmar, Mario; Gil, Fernando; Olmedo, Pablo; Ruiz-Canela, Miguel; Martínez-González, Miguel Ángel, 1957-; Salas Salvadó, Jordi; Babio, Nancy; Fitó Colomer, Montserrat; Val, José Luis del; Corella, Dolores; Sorlí, José Vicente; Ros, Emilio; Fiol, Miquel; Estruch, Ramón; Santos-Lozano, José; Arós, Fernando; Serra Majem, Lluís; Pintó Sala, Xavier; Gómez-Gracia, Enrique; Muñoz-Bravo, Carlos (MDPI, 2022)
    Background: Selenium is an essential trace mineral with potential interest for cardiovascular disease (CVD) prevention owing to its antioxidant properties. Epidemiological data on selenium status and CVD remain inconsistent. ...
  • The Effect of a Mediterranean Diet on the Incidence of Cataract Surgery
    García-Layana, Alfredo; Gianfranco, Ciufo; Toledo, Estefania; Martínez-González, Miguel Ángel, 1957-; Corella, Dolores; Fitó Colomer, Montserrat; Estruch, Ramón; Gómez-Gracia, Enrique; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Pinto, Xavier; Portillo, María P.; Sorlí, José Vicente; Bulló, Mònica; Vinyoles, Ernest; Sala Vila, Aleix; Ros, Emilio; Salas-Salvadó, Jordi; Arós, Fernando (MDPI, 2017)
    BACKGROUND: Cataract is a leading cause of vision impairment worldwide, and surgery is the only available treatment. The process that initiates lens opacification is dependent on the oxidative stress experienced by the ...

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