Browsing by Author "Gómez-Gómez, Àlex"

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  • Analysis of the interaction between tryptophan-related compounds and ATP-binding cassette transporter G2 (ABCG2) using targeted metabolomics
    García-Lino, Alba M.; Gómez-Gómez, Àlex; García-Mateos, Dafne; de la Fuente, Alvaro; Álvarez, Ana; Pozo Mendoza, Óscar J., 1975-; Merino, Gracia (Elsevier, 2021)
    ATP-binding cassette transporter G2 (ABCG2) is involved in the secretion of several compounds in milk. The in vitro and in vivo interactions between tryptophan-related compounds and ABCG2 were investigated. The tryptophan ...
  • Association between precarious employment and chronic stress: Effect of gender, stress measurement and precariousness dimensions-A cross-sectional study
    Julià Pérez, Mireia, 1981-; Méndez-Rivero, Fabrizio; Gómez-Gómez, Àlex; Pozo Mendoza, Óscar J., 1975-; Bolíbar, Mireia (MDPI, 2022)
    Precarious employment has been highlighted as a social determinant of health, given, among others, to its alleged association with chronic stress. However, few studies have been conducted analyzing such association, using ...
  • Changes in melatonin and sex steroid hormone production among men as a result of rotating night shift work - the HORMONIT study
    Harding, Barbara N.; Castaño Vinyals, Gemma; Palomar Cros, Anna; Papantoniou, Kyriaki, 1983-; Espinosa Díaz, Ana; Skene, Debra J.; Middleton, Benita; Gómez-Gómez, Àlex; Navarrete, José María; Such, Patricia; Torrejón, Antonio; Kogevinas, Manolis; Pozo Mendoza, Óscar J., 1975- (Nordic Association of Occupational Safety and Health, 2022)
    Objective: data from real world settings on circadian disruption and subsequent hormone-related changes may explain the higher risk of hormone-dependent cancers among night shift workers.The present study examines the ...
  • Effects of wine and tyrosol on the lipid metabolic profile of subjects at risk of cardiovascular disease: potential cardioprotective role of ceramides
    Rodríguez-Morató, Jose, 1987-; Boronat Rigol, Anna, 1990-; Serreli, Gabriele; Enríquez, Laura; Gómez-Gómez, Àlex; Pozo Mendoza, Óscar J., 1975-; Fitó Colomer, Montserrat; Torre Fornell, Rafael de la (MDPI, 2021)
    Ceramides are a class of sphingolipids which have recently been shown to be better cardiovascular disease (CVD) risk predictors than traditional CVD risk biomarkers. Tyrosol (TYR) is a dietary phenolic compound known to ...
  • Improving liquid chromatography-tandem mass spectrometry determination of polycarboxylic acids in human urine by chemical derivatization. Comparison of o-benzyl hydroxylamine and 2-picolyl amine
    Gómez-Gómez, Àlex; Soldevilla, Angie; Pizarro Lozano, Mª Nieves; Andreu Fernandez, Vicente; Pozo Mendoza, Óscar J., 1975- (Elsevier, 2019)
    Due to its high sensitivity and specificity, liquid chromatography-electrospray tandem mass spectrometry (LC-MS/MS) could be considered as the gold-standard in targeted metabolomics. Although LC-MS/MS allows for the direct ...
  • Metabolic signatures associated with severity in hospitalized COVID-19 patients
    Marín Corral, Judith; Rodríguez-Morató, Jose, 1987-; Gómez-Gómez, Àlex; Pascual Guàrdia, Sergi, 1979-; Muñoz-Bermúdez, Rosana; Salazar Degracia, Anna; Pérez-Terán, Purificación; Restrepo, Marcos I.; Khymenets, Olha, 1974-; Haro, Noemí; Masclans Enviz, Joan Ramon; Pozo Mendoza, Óscar J., 1975- (MDPI, 2021)
    The clinical evolution of COVID-19 pneumonia is poorly understood. Identifying the metabolic pathways that are altered early with viral infection and their association with disease severity is crucial to understand COVID-19 ...
  • Metabolomics and integrated network analysis reveal roles of endocannabinoids and large neutral amino acid balance in the ayahuasca experience
    Madrid-Gambin, Francisco; Gómez-Gómez, Àlex; Busquets Garcia, Arnau, 1985-; Haro, Noemí; Marco Sola, Santiago; Mason, Natasha L.; Reckweg, Johannes T.; Mallaroni, Pablo; Kloft, Lilian; van Oorsouw, Kim; Toennes, Stefan W.; Torre Fornell, Rafael de la; Ramaekers, Johannes G.; Pozo Mendoza, Óscar J., 1975- (Elsevier, 2022)
    There has been a renewed interest in the potential use of psychedelics for the treatment of psychiatric conditions. Nevertheless, little is known about the mechanism of action and molecular pathways influenced by ayahuasca ...
  • Nail melatonin content: a suitable non-invasive marker of melatonin production
    Gómez-Gómez, Àlex; Montero-San-Martin, Blanca; Haro, Noemí; Pozo Mendoza, Óscar J. (MDPI, 2021)
    Melatonin plays multiple physiological roles in the human body. Evaluation of melatonin production by the determination of urinary 6-sulfatoxymelatonin in 24-h samples has important drawbacks which hinder the successful ...
  • PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus
    Velasco, Eric R.; Florido Torres, Antonio Luis; Flores de los Heros, África, 1985-; Senabre, Eric; Gómez-Gómez, Àlex; Torres, Antoni; Roca, Antoni; Norrholm, Seth; Newman, Emily L.; Das, Payel; Ross, Rachel A.; Lori, A.; Pozo Mendoza, Óscar J., 1975-; Ressler, Kerry J.; Garcia-Esteve, Lluïsa; Jovanovic, Tanja; Andero, Raül (Nature Research, 2022)
    Exposure to traumatic stress can lead to fear dysregulation, which has been associated with posttraumatic stress disorder (PTSD). Previous work showed that a polymorphism in the PACAP-PAC1R (pituitary adenylate cyclase-activating ...
  • Precarious employment and stress: the biomedical embodiment of social factors. PRESSED Project Study Protocol
    Bolíbar, Mireia; Belvis, Francesc Xavier; Jódar, Pere; Vives Vergara, Alejandra, 1971-; Méndez, Fabrizio; Bartoll, Xavier; Pozo Mendoza, Óscar J., 1975-; Gómez-Gómez, Àlex; Padrosa, Eva; Benach, Joan; Julià Pérez, Mireia, 1981- (Frontiers, 2021)
    The PRESSED project aims to explain the links between a multidimensional measure of precarious employment and stress and health. Studies on social epidemiology have found a clear positive association between precarious ...
  • Sex differences in fear memory consolidation via Tac2 signaling in mice
    Florido Torres, Antonio Luis; Velasco, Eric R.; Soto-Faguás, Carlos M.; Gómez-Gómez, Àlex; Pérez-Caballero, Laura; Molina, Patricia; Nadal, Roser; Pozo Mendoza, Óscar J., 1975-; Saura, Carlos A.; Andero, Raül (Nature Research, 2021)
    Memory formation is key for brain functioning. Uncovering the memory mechanisms is helping us to better understand neural processes in health and disease. Moreover, more specific treatments for fear-related disorders such ...
  • The tryptophan system in cocaine-induced depression
    Fonseca Casals, Francina, 1972-; Mestre-Pintó, Juan Ignacio; Gómez-Gómez, Àlex; Martínez-Sanvisens, Diana; Rodríguez-Minguela, Rocío; Papaseit Fontanet, Esther; Pérez Mañá, Clara; Langohr, Klaus; Valverde Granados, Olga; Pozo Mendoza, Óscar J., 1975-; Farré Albaladejo, Magí; Pérez Mañá, Clara; Neurodep Group (MDPI, 2020)
    Major depression disorder (MDD) is the most prevalent psychiatric comorbid condition in cocaine use disorder (CUD). The comorbid MDD might be primary-MDD (CUD-primary-MDD) or cocaine-induced MDD (CUD-induced-MDD), and their ...