Browsing by Author "Gómez López, Gonzalo"

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  • ARID1A alterations are associated with FGFR3-wild type, poor-prognosis, urothelial bladder tumors
    Balbás Martínez, Cristina; Rodríguez Pinilla, María; Casanova, Ariel; Domínguez, Orlando; Pisano, David G.; Gómez López, Gonzalo; Lloreta Trull, Josep, 1958-; Lorente Garin, José Antonio; Malats i Riera, Núria; Real, Francisco X. (Public Library of Science (PLoS), 2013)
    Urothelial bladder cancer (UBC) is heterogeneous at the clinical, pathological, genetic, and epigenetic levels. Exome sequencing has identified ARID1A as a novel tumor suppressor gene coding for a chromatin remodeling ...
  • Specific contributions of cohesin-SA1 and cohesin-SA2 to TADs and polycomb domains in embryonic stem cells
    Cuadrado, Ana; Giménez-Llorente, Daniel; Kojic, Aleksandar; Rodríguez-Corsino, Miriam; Cuartero, Yasmina; Martín-Serrano, Guillermo; Gómez López, Gonzalo; Marti-Renom, Marc A.; Losada, Ana (Elsevier, 2019)
    Cohesin exists in two variants carrying either STAG/SA1 or SA2. Here we have addressed their specific contributions to the unique spatial organization of the mouse embryonic stem cell genome, which ensures super-enhancer-dependent ...
  • Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1
    Cifdaloz, Metehan; Osterloh, Lisa; Graña-Castro, Osvaldo; Riveiro-Falkenbach, Erica; Ximénez-Embún, Pilar; Muñoz, Javier; Tejedo, Cristina; Calvo, Tonantzin G.; Karras, Panagiotis; Olmeda, David; Miñana Gómez, Belén; Gómez López, Gonzalo; Cañón, Estela; Eyras Jiménez, Eduardo; Guo, Haihong; Kappes, Ferdinand; Ortíz Romero, Pablo Luis; Rodríguez Peraltó, José Luís; Megías, Diego; Valcárcel, J. (Juan); Soengas, María S. (Nature Publishing Group, 2017)
    Melanomas are well-known for their altered mRNA expression profiles. Yet, the specific contribution of mRNA binding proteins (mRBPs) to melanoma development remains unclear. Here we identify a cluster of melanoma-enriched ...
  • Whole genome analysis of p38 SAPK-mediated gene expression upon stress
    Ferreiro Neira, Isabel; Joaquin i Caudet, Manel; Islam, Abul, 1978-; Gómez López, Gonzalo; Barragan, Montserrat; Lombardía, Luís; Domínguez, Orlando; Pisano, David G.; López Bigas, Núria; Nebreda, Ángel R.; Posas Garriga, Francesc (BioMed Central, 2010)
    Background: Cells have the ability to respond and adapt to environmental changes through activation of stress-activated protein kinases (SAPKs). Although p38 SAPK signalling is known to participate in the regulation of ...