Browsing by Author "Fossati, Serena"

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  • Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview
    Vrijheid, Martine; Basagaña Flores, Xavier; Gonzalez, Juan Ramon; Porcel, Joana; Bustamante Pineda, Mariona; Casas Sanahuja, Maribel; Dadvand, Payam; Fossati, Serena; Guxens Junyent, Mònica; Maitre, Léa; Nieuwenhuijsen, Mark J.; Ortiz, Rodney; Stratakis, Nikos; Sunyer Deu, Jordi; Slama, Rémy (Wolters Kluwer (LWW), 2021)
    Early life stages are vulnerable to environmental hazards and present important windows of opportunity for lifelong disease prevention. This makes early life a relevant starting point for exposome studies. The Advancing ...
  • Association of fish consumption and mercury exposure during pregnancy with metabolic health and inflammatory biomarkers in children
    Stratakis, Nikos; Borràs, Eva; Sabidó Aguadé, Eduard, 1981-; Basagaña Flores, Xavier; Bustamante Pineda, Mariona; Casas Sanahuja, Maribel; Fossati, Serena; González Ruiz, Juan Ramón; Maitre, Léa; Urquiza, José M.; Vrijheid, Martine; Chatzi, Leda (JAMA Network, 2020)
    IMPORTANCE: The balance of mercury risk and nutritional benefit from fish intake during pregnancy for the metabolic health of offspring to date is unknown. OBJECTIVE: To assess the associations of fish intake and mercury ...
  • Association of prenatal exposure to endocrine-disrupting chemicals with liver injury in children
    Midya, Vishal; Andrušaitytė, Sandra; Basagaña Flores, Xavier; Casas Sanahuja, Maribel; Fossati, Serena; Gražulevičienė, Regina; Maitre, Léa; Urquiza, José M.; Vrijheid, Martine; Valvi, Damaskini, 1983- (American Medical Association, 2022)
    Importance: Prenatal exposures to endocrine-disrupting chemicals (EDCs) may increase the risk for liver injury in children; however, human evidence is scarce, and previous studies have not considered potential EDC-mixture ...
  • Associations of green and blue space exposure in pregnancy with epigenetic gestational age acceleration
    Marques, Irene; Santos, Susana; Monasso, Giulietta S.; Fossati, Serena; Vrijheid, Martine; Nieuwenhuijsen, Mark J.; Jaddoe, Vincent W. V.; Felix, Janine Frédérique (Taylor & Francis, 2023)
    Early life is seen as a particularly sensitive period for environmental exposures. Natural space exposure during pregnancy has been associated with offspring health. Epigenetic gestational age acceleration, a discrepancy ...
  • Early life exposure to air pollution, green spaces and built environment, and body mass index growth trajectories during the first 5 years of life: A large longitudinal study
    Bont, Jeroen de; Hughes, Rachael; Tilling, Kate; Díaz, Yesika; de Castro, Montserrat; Cirach, Marta; Fossati, Serena; Nieuwenhuijsen, Mark J.; Duarte Salles, Talita, 1985-; Vrijheid, Martine (Elsevier, 2020)
    Urban environments are characterized by multiple exposures that may influence body mass index (BMI) growth in early life. Previous studies are few, with inconsistent results and no evaluation of simultaneous exposures. ...
  • Early-life environmental exposures and childhood obesity: an exposome-wide approach
    Vrijheid, Martine; Fossati, Serena; Maitre, Léa; Márquez, Sandra; Casas Sanahuja, Maribel; de Castro, Montserrat; Donaire González, David; Robinson, Oliver; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Urquiza, José M.; Valentín, Antònia; Warembourg, Charline; Nieuwenhuijsen, Mark J.; Basagaña Flores, Xavier; Chatzi, Leda (National Institute of Environmental Health Sciences, 2020)
    Background: Chemical and nonchemical environmental exposures are increasingly suspected to influence the development of obesity, especially during early life, but studies mostly consider single exposure groups. Objectives: ...
  • Exposure to natural environments during pregnancy and birth outcomes in 11 European birth cohorts
    Torres Roda, Maria; Fossati, Serena; de Castro, Montserrat; Fernandes, Amanda; Roumeliotaki, Theano; Sunyer Deu, Jordi; Vafeiadi, Marina, 1983-; Nieuwenhuijsen, Mark J.; Vrijheid, Martine; Foraster Pulido, Maria, 1984-; Dadvand, Payam (Elsevier, 2022)
    Research suggests that maternal exposure to natural environments (i.e., green and blue spaces) promotes healthy fetal growth. However, the available evidence is heterogeneous across regions, with very few studies on the ...
  • Human Early Life Exposome (HELIX) study: a European population-based exposome cohort
    Maitre, Léa; De Bont, Jeroen, 1989-; Casas Sanahuja, Maribel; Robinson, Oliver; Basagaña Flores, Xavier; Borràs, Eva; Bustamante Pineda, Mariona; de Castro, Montserrat; Donaire González, David; Estivill, Xavier, 1955-; Fossati, Serena; González, Juan Ramón; Hernández-Ferrer, Carles; Júlvez Calvo, Jordi; Manzano Salgado, Cyntia Beatriz, 1987-; Sabidó Aguadé, Eduard, 1981-; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Urquiza, José M.; van Gent, Diana; Vives Usano, Marta, 1990-; Warembourg, Charline; Nieuwenhuijsen, Mark J.; Vrijheid, Martine (BMJ Publishing Group, 2018)
    PURPOSE: Essential to exposome research is the collection of data on many environmental exposures from different domains in the same subjects. The aim of the Human Early Life Exposome (HELIX) study was to measure and ...
  • Infection induced SARS-CoV-2 seroprevalence and heterogeneity of antibody responses in a general population cohort study in Catalonia Spain
    Karachaliou, Marianna; Moncunill, Gemma; Espinosa Díaz, Ana; Castaño Vinyals, Gemma; Jiménez, Alfons; Vidal, Marta; Santano, Rebeca; Barrios, Diana; Jiménez, Alfons; Puyol, Laura; Mayer, Leonie; Rubio, Rocío; O'Callaghan Gordo, Cristina; Fossati, Serena; Rivas, Ioar; Vrijheid, Martine; Izquierdo, Luis; Aguilar, Ruth; Basagaña Flores, Xavier; García Aymerich, Judith; Dobaño, Carlota; Kogevinas, Manolis (Nature Research, 2021)
    Sparse data exist on the complex natural immunity to SARS-CoV-2 at the population level. We applied a well-validated multiplex serology test in 5000 participants of a general population study in Catalonia in blood samples ...
  • Lutein and zeaxanthin intake during pregnancy and visual function in offspring at 11-12 years of age
    Anderson, Martin J.; Romaguera Bosch, Dora; Saint-Amour, Dave; Fossati, Serena; Fochs, Silvia; Pey, Núria; Vrijheid, Martine; Júlvez Calvo, Jordi (MDPI, 2022)
    (1) Background: Lutein and zeaxanthin (L&Z) are essential dietary nutrients that are a crucial component of the human macula, contributing to visual functioning. They easily cross the placental barrier, so that retinal ...
  • Obesity is associated with shorter telomeres in 8 year-old children
    Clemente Batalha Pardal, Diana, 1990-; Maitre, Léa; Bustamante Pineda, Mariona; Chatzi, Leda; Roumeliotaki, Theano; Fossati, Serena; Gražulevičienė, Regina; Gützkow, Kristine B.; Lepeule, Johanna; Martens, Dries S.; McEachan, Rosemary R.C.; Meltzer, Helle Margrete; Petraviciene, Inga; Slama, Rémy; Tamayo-Uria, Ibon; Urquiza, José M.; Vafeiadi, Marina, 1983-; Wright, John; Nawrot, Tim S.; Vrijheid, Martine (Nature Research, 2019)
    Telomere length is considered a biomarker of biological aging. Shorter telomeres and obesity have both been associated with age-related diseases. To evaluate the association between various indices of obesity with leukocyte ...
  • Prenatal air pollution exposure and growth and cardio-metabolic risk in preschoolers
    Fossati, Serena; Valvi, Damaskini, 1983-; Martínez, David; Cirach, Marta; Estarlich, Marisa; Fernández Somoano, Ana; Guxens Junyent, Mònica; Iñiguez, Carmen; Irizar, Amaia; Lertxundi, Aitana; Nieuwenhuijsen, Mark J.; Tamayo-Uria, Ibon; Vioque, Jesus; Tardón, Adonina; Sunyer Deu, Jordi; Vrijheid, Martine (Elsevier, 2020)
    Objectives: We investigated the association between outdoor air pollutants exposure in the first trimester of pregnancy, and growth and cardio-metabolic risk at four years of age, and evaluated the mediating role of birth ...
  • Prenatal and childhood exposure to air pollution and traffic and the risk of liver injury in European children
    Garcia, Erika; Maitre, Léa; Basagaña Flores, Xavier; Casas Sanahuja, Maribel; de Castro, Montserrat; Fossati, Serena; Nieuwenhuijsen, Mark J.; Urquiza, José M.; Vrijheid, Martine; Chatzi, Leda (Wolters Kluwer (LWW), 2021)
    Background: Nonalcoholic fatty liver disease is the most prevalent pediatric chronic liver disease. Experimental studies suggest effects of air pollution and traffic exposure on liver injury. We present the first large-scale ...
  • Prenatal and postnatal exposure to PFAS and cardiometabolic factors and inflammation status in children from six European cohorts
    Papadopoulou, Eleni, 1985-; Basagaña Flores, Xavier; Casas Sanahuja, Maribel; Fossati, Serena; Maitre, Léa; Sabidó Aguadé, Eduard, 1981-; Borràs, Eva; Urquiza, José M.; Vrijheid, Martine; Chatzi, Leda (Elsevier, 2021)
    Developing children are particularly vulnerable to the effects of exposure to per- and polyfluoroalkyl substances (PFAS), a group of endocrine disrupting chemicals. We hypothesized that early life exposure to PFASs is ...
  • Prenatal exposure to phthalates and phenols and preclinical vascular health during early adolescence
    Montazeri, Parisa, 1988-; Fossati, Serena; Warembourg, Charline; Casas Sanahuja, Maribel; Clemente Batalha Pardal, Diana, 1990-; Garcia-Esteban, Raquel; Nawrot, Tim S.; Vrijheid, Martine (Elsevier, 2022)
    Background and aim: Exposure to endocrine-disrupting chemicals may increase cardiovascular risk from early life, but studies in children have shown inconsistent results, most focused on analysis of single chemicals, and ...
  • Risk and protective factors for bullying at 11 years of age in a Spanish Birth Cohort Study
    Babarro, Izaro; Andiarena, Ainara; Fano, Eduardo; Lertxundi, Nerea; Vrijheid, Martine; Julvez, Jordi; Barreto, Florencia B.; Fossati, Serena; Ibarluzea, Jesús (MDPI, 2020)
    (1) Background: Bullying affects a large number of children worldwide. This study has two objectives, to provide data on the prevalence of bullying in Spain, and to identify risk and protective factors associated with ...
  • Urban environment and health behaviours in children from six European countries
    Fernández-Barrés, Sílvia; Fossati, Serena; Márquez, Sandra; Basagaña Flores, Xavier; Bont, Jeroen de; de Castro, Montserrat; Maitre, Léa; Nieuwenhuijsen, Mark J.; Romaguera Bosch, Dora; Urquiza, José M.; Chatzi, Leda; Vrijheid, Martine (Elsevier, 2022)
    Background: Urban environmental design is increasingly considered influential for health and wellbeing, but evidence is mostly based on adults and single exposure studies. We evaluated the association between a wide range ...
  • Urban environment and obesity and weight-related behaviours in primary school children
    De Bont, Jeroen, 1989-; Márquez, Sandra; Fernández-Barrés, Sílvia; Warembourg, Charline; Koch, Sarah; Persavento, Cecilia; Fochs, Silvia; Pey, Núria; de Castro, Montserrat; Fossati, Serena; Nieuwenhuijsen, Mark J.; Basagaña Flores, Xavier; Casas Sanahuja, Maribel; Duarte Salles, Talita, 1985-; Vrijheid, Martine (Elsevier, 2021)
    Background: Urban environments are characterised by many factors that may influence children's lifestyle and increase the risk of childhood obesity, but multiple urban exposures have scarcely been studied. Objective: We ...
  • Urinary metabolic biomarkers of diet quality in European children are associated with metabolic health
    Stratakis, Nikos; Maitre, Léa; Fernández-Barrés, Sílvia; Basagaña Flores, Xavier; Casas Sanahuja, Maribel; Fossati, Serena; Borràs, Eva; Sabidó Aguadé, Eduard, 1981-; Urquiza, José M.; Vrijheid, Martine; Chatzi, Leda (eLife, 2022)
    Urinary metabolic profiling is a promising powerful tool to reflect dietary intake and can help understand metabolic alterations in response to diet quality. Here, we used 1H NMR spectroscopy in a multicountry study in ...