Browsing by Author "Fornas Carreño, Oscar"

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  • A new chromosome-assigned Mongolian gerbil genome allows characterization of complete centromeres and a fully heterochromatic chromosome
    Brekke, Thomas D.; Papadopulos, Alexander S. T.; Julià, Eva; Fornas Carreño, Oscar; Fu, Beiyuan; Yang, Fengtang; Fuente, Roberto de la; Page, Jesus; Baril, Tobias; Hayward, Alexander; Mulley, John F. (Oxford University Press, 2023)
    Chromosome-scale genome assemblies based on ultralong-read sequencing technologies are able to illuminate previously intractable aspects of genome biology such as fine-scale centromere structure and large-scale variation ...
  • Deciphering the Human Virome with Single-Virus Genomics and Metagenomics
    de la Cruz Peña, María Jose; Martínez Hernández, Francisco; García Heredia, Inmaculada; Lluesma Gómez, Mónica; Fornas Carreño, Oscar; Martínez García, Manuel (MDPI, 2018)
    Single-cell genomics has unveiled the metabolic potential of dominant microbes inhabiting different environments, including the human body. The lack of genomic information for predominant microbes of the human body, such ...
  • Ecogenomics of the SAR11 clade
    Haro Moreno, Jose M.; Rodríguez Valera, Francisco; Rosselli, Riccardo; Martínez Hernández, Francisco; Roda García, Juan J.; Lluesma Gómez, Mónica; Fornas Carreño, Oscar; Martínez García, Manuel; López Pérez, Mario (Wiley, 2020)
    Members of the SAR11 clade, despite their high abundance, are often poorly represented by metagenome-assembled genomes. This fact has hampered our knowledge about their ecology and genetic diversity. Here we examined 175 ...
  • Flow sorting enrichment and nanopore sequencing of chromosome 1 from a Chinese individual
    Kuderna, Lukas F.K.; Solís Moruno, Manuel, 1993-; Batlle Masó, Laura, 1993-; Julià, Eva; Lizano González, Esther, 1974-; Anglada Busquets, Roger; Ramírez Bautista, Eva; Bote, Alex; Tormo, Marc; Marquès i Bonet, Tomàs, 1975-; Fornas Carreño, Oscar; Casals López, Ferran (Frontiers Media, 2020)
    Sorting of individual chromosomes by Flow Cytometry (flow-sorting) is an enrichment method to potentially simplify genome assembly by isolating chromosomes from the context of the genome. We have recently developed a ...
  • Into the dark: exploring the deep ocean with single-virus genomics
    Martínez Hernández, Francisco; Fornas Carreño, Oscar; Martínez García, Manuel (MDPI, 2022)
    Single-virus genomics (SVGs) has been successfully applied to ocean surface samples allowing the discovery of widespread dominant viruses overlooked for years by metagenomics, such as the uncultured virus vSAG 37-F6 infecting ...
  • Selective single molecule sequencing and assembly of a human Y chromosome of African origin
    Kuderna, Lukas F.K.; Lizano González, Esther, 1974-; Julià, Eva; Gómez Garrido, Jèssica; Serres Armero, Aitor, 1992-; Kuhlwilm, Martin; Alandes, Regina Antoni; Alvarez-Estape, Marina; Juan, David; Simon, Heath; Alioto, Tyler; Gut, Marta; Gut, Ivo Glynne; Schierup, Mikkel H.; Fornas Carreño, Oscar; Marquès i Bonet, Tomàs, 1975- (Nature Research, 2019)
    Mammalian Y chromosomes are often neglected from genomic analysis. Due to their inherent assembly difficulties, high repeat content, and large ampliconic regions, only a handful of species have their Y chromosome properly ...
  • Single-virus genomics reveals hidden cosmopolitan and abundant viruses
    Martínez Hernández, Francisco; Fornas Carreño, Oscar; Lluesma Gómez, Mónica; Bolduc, Benjamin; de la Cruz Peña, María Jose; Martínez Martínez, Joaquín; Antón, Josefa; Gasol, Josep M.; Rosselli, Riccardo; Rodríguez Valera, Francisco; Sullivan, Matthew; Acinas, Silvia G.; Martínez García, Manuel (Nature Publishing Group, 2017)
    Microbes drive ecosystems under constraints imposed by viruses. However, a lack of virus genome information hinders our ability to answer fundamental, biological questions concerning microbial communities. Here we apply ...
  • Three-dimensional genomic structure and cohesin occupancy correlate with transcriptional activity during spermatogenesis
    Vara, Covadonga; Paytuví Gallart, Andreu; Cuartero, Yasmina; Le Dily, François; Garcia, Francisca; Salvà-Castro, Judit; Gómez-H, Laura; Julià, Eva; Moutinho, Catia; Aiese Cigliano, Riccardo; Sanseverino, Walter; Fornas Carreño, Oscar; Pendás, Alberto M.; Heyn, Holger; Waters, Paul D.; Marti-Renom, Marc A.; Ruiz Herrera, Aurora (Elsevier, 2019)
    Mammalian gametogenesis involves dramatic and tightly regulated chromatin remodeling, whose regulatory pathways remain largely unexplored. Here, we generate a comprehensive high-resolution structural and functional atlas ...
  • Transcriptome innovations in primates revealed by single-molecule long-read sequencing
    Ferrández Peral, Luis, 1991-; Zhan, Xiaoyu; Zhan, Xiaoyu; Alvarez-Estape, Marina; Chiva, Cristina; Esteller Cucala, Paula; García Pérez, Raquel, 1989-; Julià, Eva; Lizano González, Esther, 1974-; Fornas Carreño, Oscar; Sabidó Aguadé, Eduard, 1981-; Li, Qiye; Marquès i Bonet, Tomàs, 1975-; Juan, David; Zhang, Guojie (Cold Spring Harbor Laboratory Press (CSHL Press), 2022)
    Transcriptomic diversity greatly contributes to the fundamentals of disease, lineage-specific biology, and environmental adaptation. However, much of the actual isoform repertoire contributing to shaping primate evolution ...
  • Y chromosome sequence and epigenomic reconstruction across human populations
    Esteller Cucala, Paula; Palmada-Flores, Marc; Kuderna, Lukas F.K.; Fontseré Alemany, Clàudia, 1992-; Serres Armero, Aitor, 1992-; Dabad, Marc; Torralvo, María; Faella, Armida; Ferrández Peral, Luis, 1991-; Llovera Nadal, Laia; Fornas Carreño, Oscar; Julià, Eva; Ramírez, Erika; González, Irene; Hecht, Jochen; Lizano González, Esther, 1974-; Juan, David; Marquès i Bonet, Tomàs, 1975- (Nature Research, 2023)
    Recent advances in long-read sequencing technologies have allowed the generation and curation of more complete genome assemblies, enabling the analysis of traditionally neglected chromosomes, such as the human Y chromosome ...