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Browsing by Author "Fillat i Fonts, Cristina"
Now showing items 1-14 of 14
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Luque, Juan; Mendes, Ingrid; Gómez, Beatriz; Morte, Beatriz; López de Heredia, Miguel de; Herreras, Enrique; Corrochano, Virginia; Bueren, Juan; Gallano, Pía; Artuch, Rafael; Fillat i Fonts, Cristina; Pérez Jurado, Luis Alberto; Montoliu, Lluis; Carracedo, Ángel; Millán, José M.; Webb, Susan M.; Palau, Francesc; CIBERER Network; Lapunzina, Pablo Daniel (Wiley, 2022)CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). ...
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Villanueva, Eneko; Martí Solano, Maria; Fillat i Fonts, Cristina (Nature Publishing group, 2016)Codon usage adaptation of lytic viruses to their hosts is determinant for viral fitness. In this work, we analyzed the codon usage of adenoviral proteins by principal component analysis and assessed their codon adaptation ...
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Rozen, Esteban J.; Roewenstrunk, Julia Maria, 1981-; Barallobre, María José; Di Vona, Chiara, 1981-; Jung, Carole; Figueiredo, Ana F.; Luna, Jeroni; Fillat i Fonts, Cristina; Arbonés de Rafael, Maria Lourdes, 1959-; Graupera, Mariona; Valverde, M. A. (Miguel Ángel), 1963-; Luna Gargantilla, Susana de la (Elsevier, 2018)Angiogenesis is a highly regulated process essential for organ development and maintenance, and its deregulation contributes to inflammation, cardiac disorders, and cancer. The Ca2+/nuclear factor of activated T cells ...
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Grau, Cristina; Arató, Krisztina, 1981-; Fernández-Fernández, José Manuel, 1967-; Valderrama, Aitana; Sindreu, Carlos; Fillat i Fonts, Cristina; Ferrer, Isidre; Luna, Susana de la; Altafaj, Xavier (Frontiers, 2014)N-methyl-D-aspartate glutamate receptors (NMDARs) play a pivotal role in neural development and synaptic plasticity, as well as in neurological disease. Since NMDARs exert their function at the cell surface, their density ...
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Ortiz Abalia, Jon (Universitat Pompeu Fabra, 2008-05-15)DYRK1A es uno de los principales genes candidatos que podrían explicar algunos de los defectos neurológicos asociados al fenotipo Síndrome de Down (SD); desde el retraso mental, rasgo común a todos los individuos con SD ...
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Abate-Daga, Daniel (Universitat Pompeu Fabra, 2009-04-17)El sistema TK/GCV es, problamente, la estrategia suicida mejor caracterizada hasta el momento. No obstante, se desconocen muchos aspectos relacionados con su mecanismo de acción. Con el objetivo de indentificar condicionantes ...
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Bofill-De Ros, Xavier; Santos, Mónica; Vila-Casadesús, Maria; Villanueva, Eneko; Andreu Somavilla, Núria; Dierssen, Mara; Fillat i Fonts, Cristina (BioMed Central, 2015)Background. Down syndrome (DS) or trisomy 21 is the result of a genetic dosage imbalance that translates in a broad clinical spectrum. A major challenge in the study of DS is the identification of functional genetic elements ...
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José Segarra-Martínez, Anabel; Sobrevals, Luciano; Ivorra Cano, Antoni, 1974-; Fillat i Fonts, Cristina (Elsevier, 2012)Pancreatic Ductal Adenocarcinoma (PDAC) therapies show limited success./nIrreversible electroporation (IRE) is an innovative loco-regional therapy in which highvoltage pulses are applied to induce plasma membrane defects ...
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Garcia Rodríguez, Laura (Universitat Pompeu Fabra, 2008-06-26)L'adenocarcinoma ductal de pàncrees és un càncer molt agressiu que actualment representa la quarta causa de mort per càncer als països occidentals. Les teràpies clàssiques, basades en la resecció quirúrgica, la radioteràpia ...
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José Segarra-Martínez, Anabel (Universitat Pompeu Fabra, 2011-12-13)Els tractaments actuals pel càncer de pàncreas presenten un eficàcia limitada de manera que es necessari el desenvolupament de noves teràpies antitumorals. La teràpia gènica pel càncer de pàncreas basada en l’ús d’adenovirus ...
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Boni, Jacopo, 1987-; Rubio Pérez, Carlota, 1990-; López Bigas, Núria; Fillat i Fonts, Cristina; Luna, Susana de la (MDPI, 2020)DYRK (dual-specificity tyrosine-regulated kinases) are an evolutionary conserved family of protein kinases with members from yeast to humans. In humans, DYRKs are pleiotropic factors that phosphorylate a broad set of ...
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Martínez Bosch, Neus; Enrique Guerrero, Pedro; Moreno, Mireia; José Segarra-Martínez, Anabel; Iglesias García, Mar; Munné-Collado, Jessica; Anta Rodríguez, Héctor, 1988-; Gibert, Joan; Orozco, Carlos Alberto; Vinaixa Forner, Judith, 1991-; Fillat i Fonts, Cristina; Viñals, Francesc; Navarro Medrano, Pilar (Impact Journals, 2016)Current treatments for pancreatic ductal adenocarcinoma (PDA) are ineffective, making this the 4th leading cause of cancer deaths. Sunitinib is a broad-spectrum inhibitor of tyrosine kinase receptors mostly known for its ...
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Murillo-Cuesta, Silvia; Artuch, Rafael; Asensio, Fernando; Villa, Pedro de la; Dierssen, Mara; Enríquez, Jose Antonio; Fillat i Fonts, Cristina; Fourcade, Stéphane; Ibáñez, Borja; Montoliu, Lluis; Oliver, Eduardo; Pujol, Aurora, 1968-; Salido, Eduardo; Vallejo, Mario; Varela Nieto, Isabel (Frontiers, 2020)Animal models are invaluable for biomedical research, especially in the context of rare diseases, which have a very low prevalence and are often complex. Concretely mouse models provide key information on rare disease ...
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Villanueva, Eneko; Navarro Medrano, Pilar; Rovira-Rigau, Maria; Sibilio, Annarita; Méndez Giraldez, Raúl; Fillat i Fonts, Cristina (Nature Publishing Group, 2017)Systemic treatment of cancer requires tumour-selective therapies that eliminate cancer cells yet preserve healthy tissues from undesired damage. Tumoral transformation is associated with profound effects in translational ...
Now showing items 1-14 of 14
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