Browsing by Author "Fernández-Zapico, Martin E."

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  • Poly(ADP-Ribose) Polymerases: New Players in the Pathogenesis of Exocrine Pancreatic Diseases.
    Martínez Bosch, Neus; Fernández-Zapico, Martin E.; Navarro Medrano, Pilar; Yélamos López, José (Elsevier, 2016)
    The poly(ADP-ribose) polymerase (PARP) enzymes were initially characterized as sensors of DNA breaks but are now known to play key roles not only in the DNA damage response but also in regulating numerous molecular processes, ...
  • Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk
    Orozco, Carlos Alberto; Martínez Bosch, Neus; Enrique Guerrero, Pedro; Vinaixa Forner, Judith, 1991-; Dalotto-Moreno, Tomás; Iglesias García, Mar; Moreno, Mireia; Djurec, Magdolna; Poirier, Françoise; Gabius, Hans J.; Fernández-Zapico, Martin E.; Hwang, Rosa F.; Guerra, Carmen; Rabinovich, Gabriel A.; Navarro Medrano, Pilar (National Academy of Sciences, 2018)
    Pancreatic ductal adenocarcinoma (PDA) remains one of the most lethal tumor types, with extremely low survival rates due to late diagnosis and resistance to standard therapies. A more comprehensive understanding of the ...

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