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Browsing by Author "Fernández Rodríguez, M. Concepción"

Browsing by Author "Fernández Rodríguez, M. Concepción"

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  • Anti-tumor activity of the combination of bendamustine with vorinostat in diffuse large B-cell lymphoma cells.
    Fernández Rodríguez, M. Concepción; Salar Silvestre, Antonio; Navarro, Alfons; Gimeno Vázquez, Eva; Pairet García, Silvia; Camacho Díaz, Laura; Ferraro Rosset, Mariana Paola; Serrano Figueras, Sergi; Besses Raebel, Carles; Bellosillo Paricio, Beatriz; Sanchez Gonzalez, Blanca (Taylor & Francis, 2016)
    Current standard-of-care therapy for diffuse large B-cell lymphoma (DLBCL) results in up to 40% of patients who either relapse or develop refractory disease. In this setting, further therapeutic improvements are needed. ...
  • Case report: High doses of intravenous immunoglobulins as a successful treatment for late onset immune agranulocytosis after rituximab plus bendamustine
    Díez-Feijóo, Ramón; Rodríguez-Sevilla, Juan José; Fernández Rodríguez, M. Concepción; Flores, Solange; Raya, Carmen; Ferrer, Ana; Colomo Saperas, Luis Alberto; Salar Silvestre, Antonio (Frontiers, 2022)
    Late onset neutropenia (LON) related to rituximab or rituximab plus chemotherapy is defined as an unexplained absolute neutrophil count of ≤1.5 × 109/L starting at least four weeks after the last rituximab administration. ...
  • Characterization of CD34+ hematopoietic progenitor cells in JAK2V617F and CALR-mutated myeloproliferative neoplasms.
    Angona Figueras, Anna; Álvarez Larrán, Alberto; Bellosillo Paricio, Beatriz; Longarón Rozalen, Raquel; Camacho Díaz, Laura; Fernández Rodríguez, M. Concepción; Pairet García, Silvia; Besses Raebel, Carles (Elsevier, 2016)
    Mutations in JAK2 or CALR are observed in patients with myeloproliferative neoplasms (MPN). To get further insight in the dynamics of the mutant clone, we assessed the mutant allele burden in hematopoietic stem cells (HSCs), ...
  • Evaluation of four prognostic indices in follicular lymphoma treated in first line with immunochemotherapy
    Rodríguez-Sevilla, Juan José; Fernández Rodríguez, M. Concepción; Bento, Leyre; Díez-Feijóo, Ramón; Felipe Pinzon, Sergio; Gibert Fernandez, Joan 1988-; Fernández-Ibarrondo, Lierni; Lafuente, Marta; Ferrer Del Alamo, Ana; Sánchez González, Blanca; Gimeno Vázquez, Eva; Sainz, Juan; Ramos-Asensio, Rafael; García, Juan Fernando; Colomo Saperas, Luis Alberto; Bellosillo Paricio, Beatriz; Gutierrez, Antonio; Salar Silvestre, Antonio (American Society of Hematology, 2022)
    Several clinical risk models have been proposed to predict outcome in follicular lymphoma (FL). The development of Next Generation Sequencing (NGS) technologies has allowed the integration of somatic gene mutations in ...
  • First description of the t(3;17) (q27;q21)/IGF2BP2::LSM12 translocation in marginal zone lymphoma
    Díez-Feijóo, Ramón; Fernández Rodríguez, M. Concepción; Lafuente, Marta; García Gisbert, Nieves, 1994-; Ferrer Del Alamo, Ana; Colomo Saperas, Luis Alberto; Salido Galeote, Marta; Salar Silvestre, Antonio (American Society of Hematology, 2023)
  • Genetic characterization and clinical features of helicobacter pylori negative gastric mucosa-associated lymphoid tissue lymphoma
    Kiesewetter, Barbara; Salar Silvestre, Antonio; Fernández Rodríguez, M. Concepción; Du, Ming Qing (MDPI, 2021)
    Background: In Western countries, the prevalence of gastric mucosa-associated lymphoid tissue (MALT) lymphoma has declined over the last three decades. Contemporaneously, H. pylori negative gastric MALT lymphoma is ...
  • Impact of genotype on leukaemic transformation in polycythaemia vera and essential thrombocythaemia
    Alvarez-Larrán, Alberto; Senín Magan, Maria Alicia; Fernández Rodríguez, M. Concepción; Pereira, Arturo; Arellano-Rodrigo, Arturo; Gómez, Montse; Ferrer-Marín, Francisca; Martínez-López, Joaquín; Camacho Díaz, Laura; Colomer Pujol, Dolors; Angona Figueras, Anna; Navarro, Blanca; Cervantes, Francisco; Besses Raebel, Carles; Bellosillo Paricio, Beatriz; Hernández-Boluda, Juan Carlos (Wiley, 2017)
    The influence of driver mutations on leukaemic transformation was analysed in 1747 patients with polycythaemia vera or essential thrombocythaemia. With a median follow-up of 7·2 years, 349 patients died and 62 progressed ...
  • Masked polycythaemia vera: presenting features, response to treatment and clinical outcomes.
    Álvarez Larrán, Alberto; Angona Figueras, Anna; Ancochea Serra, Agueda; García-Pallarols, Francesc; Fernández Rodríguez, M. Concepción; Longarón Rozalen, Raquel; Bellosillo Paricio, Beatriz; Besses Raebel, Carles (Wiley, 2016)
    Masked polycythaemia vera (PV) has been proposed as a new entity with poorer outcome than overt PV. In this study, the initial clinical and laboratory characteristics, response to treatment and outcome of masked and overt ...
  • MicroRNAs 142-3p, miR-155 and miR-203 are deregulated in gastric MALT LymphomasCompared to chronic gastritis
    Fernández Rodríguez, M. Concepción; Bellosillo Paricio, Beatriz; Ferraro Rosset, Mariana Paola; Seoane, Agustín; Sanchez Gonzalez, Blanca; Pairet García, Silvia; Pons, A.; Barranco Sanz, Luis Carlos; Vela Ortíz, María del Carmen; Gimeno Vázquez, Eva; Colomo Saperas, Luis Alberto; Besses Raebel, Carles; Navarro, Alfons; Salar Silvestre, Antonio (International Institute of Anticancer Research (IIAR), 2017)
    BACKGROUND: Over the last years, our knowledge on pathogenesis of gastric MALT lymphoma has greatly improved, but its morphological diagnosis is still hampered by overlapping histological features with advanced chronic ...
  • miR-203 and miR-221 regulate SOCS1 and SOCS3 in essential thrombocythemia.
    Navarro, A.; Pairet García, Silvia; Álvarez Larrán, Alberto; Pons, A.; Ferrer, G.; Longarón Rozalen, Raquel; Fernández Rodríguez, M. Concepción; Camacho Díaz, Laura; Monzó, M.; Besses Raebel, Carles; Bellosillo Paricio, Beatriz (Nature Publishing Group, 2016)
    The biological basis of essential thrombocythemia (ET) patients lacking known mutations is still unknown. MicroRNAs (miRNA) regulate hematopoietic differentiation and are deregulated in several hematopoietic malignancies. ...
  • Molecular and cytogenetic characterization of myelodysplastic syndromes in cell-free DNA
    García Gisbert, Nieves, 1994-; Garcia-Ávila, Sara; Merchán, Brayan; Salido Galeote, Marta; Fernández Rodríguez, M. Concepción; Gibert Fernandez, Joan 1988-; Fernández-Ibarrondo, Lierni; Camacho Díaz, Laura; Lafuente, Marta; Longarón Rozalen, Raquel; Espinet Solà, Blanca; Vélez, Patricia; Pujol Vallverdú, Ramon Maria; Andrade-Campos, Marcio; Arenillas Rocha, Leonor; Salar Silvestre, Antonio; Calvo Gonzalo, Xavier; Besses Raebel, Carles; Bellosillo Paricio, Beatriz (American Society of Hematology, 2022)
    Molecular and cytogenetic studies are essential for diagnosis and prognosis in patients with myelodysplastic syndromes (MDSs). Cell-free DNA (cfDNA) analysis has been reported to be a reliable noninvasive approach for ...
  • Outcomes and molecular profile of oligomonocytic CMML support its consideration as the first stage in the CMML continuum
    Calvo González, Xavier; Roman-Bravo, David; García Gisbert, Nieves, 1994-; Rodriguez-Sevilla, Juan José; García-Avila, Sara; Florensa Brichs, Lourdes; Gibert Fernandez, Joan 1988-; Fernández Rodríguez, M. Concepción; Salido Galeote, Marta; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Colomo Saperas, Luis Alberto; Bellosillo Paricio, Beatriz; Ferrer, Ana; Arenillas Rocha, Leonor (American Society of Hematology, 2022)
    atients with oligomonocytic chronic myelomonocytic leukemia (OM-CMML) are currently classified according to the 2017 World Health Organization myelodysplastic syndromes classification. However, recent data support considering ...
  • Screening for prognostic microRNAs associated with treatment failure in diffuse large B cell lymphoma
    Bento, Leyre; Vögler, Oliver; Sas-Barbeito, Adriana; Muncunill, Josep; Ros, Teresa; Martínez, Jordi; Quintero-Duarte, Adriana; Ramos, Rafel; Asensio, Víctor Jose; Fernández Rodríguez, M. Concepción; Salar Silvestre, Antonio; Navarro, Alfons; Del Campo, Raquel; Ibarra, Javier; Alemany, Regina; Gutiérrez, Antonio (MDPI, 2022)
    Diffuse large B cell lymphoma (DLBCL) treatment with R-CHOP regimen produces 5-year progression-free survival and overall survival of around 60-70%. Our objective was to discover prognostic biomarkers allowing early detection ...