Browsing by Author "Felip, Enriqueta"

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  • A phase Ib/II study of HER3-targeting lumretuzumab in combination with carboplatin and paclitaxel as first-line treatment in patients with advanced or metastatic squamous non-small cell lung cancer
    Cejalvo, Juan M.; Jacob, Wolfgang; Fleitas Kanonnikoff, Tania; Felip, Enriqueta; Navarro Mendivil, Alejandro; Martínez-García, Maria; Taus García, Álvaro; Leighl, Natasha; Lassen, Ulrik; Mau-Soerensen, Morten; Adessi, Celine; Michielin, Francesca; James, Ian; Ceppi, Maurizio; Hasmann, Max; Weisser, Martin; Cervantes, Andrés (BMJ Publishing Group, 2019)
    PURPOSE:This study investigated the safety and clinical activity of lumretuzumab, a humanised antihuman epidermal growth factor receptor 3 (HER3) monoclonal antibody, in combination with carboplatin and paclitaxel in ...
  • Dual MET and ERBB inhibition overcomes intratumor plasticity in osimertinib-resistant-advanced non-small-cell lung cancer (NSCLC)
    Martinez-Marti, Alex; Felip, Enriqueta; Matito, Judit; Mereu, Elisabetta; Navarro, Alejandro; Cedrés, Susana; Pardo, Núria; Martines de Castro, Ana; Remon, Jordi; Miquel, Josep M.; Guillaumet-Adkins, Amy; Nadal, Ernest; Rodríguez Esteban, Gustavo; Arqués, Oriol; Fasani, Roberta; Nuciforo, Paolo G.; Heyn, Holger; Villanueva, Alberto; Palmer, Héctor G.; Vivancos Prellezo, Ana (Oxford University Press, 2017)
    BACKGROUND: Third-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) such as osimertinib are the last line of targeted treatment of metastatic non-small-cell lung cancer (NSCLC) EGFR-mutant ...
  • Five latent factors underlie response to immunotherapy
    Usset, Joseph; Rosendahl Huber, Axel; Andrianova, Maria A.; Batlle Gómez, Eduard; Carles, Joan; Cuppen, Edwin; Elez, Elena; Felip, Enriqueta; Gómez Rey, Marina; Lo Giacco, Deborah; Martínez Jiménez, Francisco; Muñoz Couselo, Eva; Siu, Lillian L.; Tabernero Cartula, Josep; Vivancos Prellezo, Ana; Muiños, Ferran; Gonzalez-Perez, Abel; López Bigas, Núria (Nature Research, 2024)
    Only a subset of patients treated with immune checkpoint inhibitors (CPIs) respond to the treatment, and distinguishing responders from non-responders is a major challenge. Many proposed biomarkers of CPI response and ...
  • Single-cell transcriptome conservation in cryopreserved cells and tissues
    Guillaumet-Adkins, Amy; Rodríguez Esteban, Gustavo; Mereu, Elisabetta; Méndez Lago, María; Jaitin, Diego Adhemar; Villanueva, Alberto; Vidal, August; Martínez Martí, Alex; Felip, Enriqueta; Vivancos Prellezo, Ana; Keren-Shaul, Hadas; Heath, Simon; Gut, Marta; Amit, Ido; Gut, Ivo Glynne; Heyn, Holger (BioMed Central, 2017)
    A variety of single-cell RNA preparation procedures have been described. So far, protocols require fresh material, which hinders complex study designs. We describe a sample preservation method that maintains transcripts ...
  • Updated guidelines for predictive biomarker testing in advanced non-small-cell lung cancer: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology
    Garrido, P.; Conde, Esther; De Castro, Javier; Gómez-Román, J. J.; Felip, Enriqueta; Pijuan Andujar, Lara; Isla, Dolores; Sanz, J.; Paz-Ares, L.; López-Ríos, F. (Springer, 2020)
    In 2011 the Spanish Society of Medical Oncology (SEOM) and the Spanish Society of Pathology (SEAP) started a joint project to establish guidelines on biomarker testing in patients with advanced non-small-cell lung cancer ...

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