Browsing by Author "Fariñas, Isabel"

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  • Intron detention tightly regulates the stemness/differentiation switch in the adult neurogenic niche
    González Iglesias, Ainara; Arcas Mantas, Aida; Domingo Muelas, Ana; Mancini, Estefanía; Galcerán, Joan; Valcárcel, J. (Juan); Fariñas, Isabel; Nieto, M. Ángela (Nature Research, 2024)
    The adult mammalian brain retains some capacity to replenish neurons and glia, holding promise for brain regeneration. Thus, understanding the mechanisms controlling adult neural stem cell (NSC) differentiation is crucial. ...
  • Role of p27Kip1 as a transcriptional regulator
    Bachs Valldeneu, Oriol; Gallastegui Calvache, Edurne; Orlando, Serena; Bigas Salvans, Anna; Morante-Redolat, José Manuel; Serratosa, Joan; Fariñas, Isabel; Aligué, Rosa; Pujol, Maria Jesús (Impact Journal, 2018)
    The protein p27Kip1 is a member of the Cip/Kip family of cyclin-dependent kinase (Cdk) inhibitors. It interacts with both the catalytic and the regulatory subunit (cyclin) and introduces a region into the catalytic cleave ...

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