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Browsing by Author "Espinet Solà, Blanca"
Now showing items 1-20 of 32
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González Gascón y Marín, Isabel; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Hernández, José-Ángel; Grupo Español de Leucemia Linfática Crónica (GELLC); Grupo Cooperativo Español de Citogenética Hematológica (GCECGH) (Wiley, 2014)The prognosis of chronic lymphocytic leukemia (CLL) patients displaying trisomy 12 (+12) remains unclear. In this study, we analyzed the influence of the proportion of cells with +12, and other clinical and biologic factors, ...
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Hernández, José-Ángel; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Hernández-Rivas, Jesús María; Grupo Cooperativo Español de Citogenética Hematológica (GCECGH); Grupo Español de Leucemia Linfática Crónica (GELLC) (Public Library of Science, 2015)To analyze the impact of the 11q deleted (11q-) cells in CLL patients on the time to first therapy (TFT) and overall survival (OS), 2,493 patients with CLL were studied. 242 patients (9.7%) had 11q-. Fluorescence in situ ...
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Ramos Campoy, Silvia; Puiggros Metje, Anna Maria; Gimeno, Eva; Espinet Solà, Blanca (Ferrata Storti Foundation, 2022)Genome complexity has been associated with poor outcome in patients with chronic lymphocytic leukemia (CLL). Previous cooperative studies established five abnormalities as the cut-off that best predicts an adverse evolution ...
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Blanco Ares, Gonzalo, 1989-; Puiggros Metje, Anna Maria; Sherry, Barbara; Nonell Mazelón, Lara; Calvo Gonzalo, Xavier; Puigdecanet Riubugent, Eulàlia; Arnal, Magdalena; Rodríguez-Rivera, María; Gimeno Vázquez, Eva; Abella Monreal, Eugenia; Calon, Alexandre; Ferrer Del Alamo, Ana; Espinet Solà, Blanca (Elsevier, 2021)Several studies in chronic lymphocytic leukemia (CLL) patients have reported impaired immune cell functions, which contribute to tumor evasion and disease progression. However, studies on CLL-like monoclonal B-cell ...
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Costa, Dolors; Grau, Javier; Espinet Solà, Blanca; Arias, Amparo; Gómez, Cándida; López-Guerra, Mónica; Nomdedeu, Meritxell; Cervantes, Francisco (Spandidos Publications, Ltd., 2019)BCR/ABL1 gene fusion is the hallmark of chronic myeloid leukemia (CML), and is generated in 5-10% of patients by a variant translocation involving 9q34, 22q11.2 and one or more additional genomic regions. The objective of ...
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Chatzikonstantinou, Thomas; Espinet Solà, Blanca; Ghia, Paolo (Nature Research, 2021)Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to Coronavirus disease 2019 (COVID-19) due to age, disease, and treatment-related immunosuppression. We aimed to assess risk factors of outcome and ...
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Fuster-García, Carla; Martín-García, David; Balagué, Olga; Navarro, Alba; Nadeu, Ferran; Costa, Dolors; Prieto, Miriam; Salaverria, Itziar; Espinet Solà, Blanca; Rivas-Delgado, Alfredo; Terol, María-José; Giné, Eva; Forcada, Pilar; Ashton-Key, Margaret; Puente, Xosé S.; Swerdlow, Steven H.; Beà, Sílvia; Campo, Elias (Ferrata Storti Foundation, 2020)
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Baliakas, Panagiotis; Espinet Solà, Blanca; Mellink, Clemens; Jarosova, Marie; Athanasiadou, Anastasia; Ghia, Paolo; Kater, Arnon P.; Oscier, David; Haferlach, Claudia; Stamatopoulos, Kostas (Wolters Kluwer (LWW), 2022)Mounting evidence underscores the clinical value of cytogenetic analysis in chronic lymphocytic leukemia (CLL), particularly as it allows the identification of complex karyotype, that has recently emerged as a prognostic ...
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Mansouri, Larry; Espinet Solà, Blanca; Rosenquist, Richard (Nature Research, 2022)Recent evidence suggests that the prognostic impact of gene mutations in patients with chronic lymphocytic leukemia (CLL) may differ depending on the immunoglobulin heavy variable (IGHV) gene somatic hypermutation (SHM) ...
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Rack, K. A.; van den Berg-de-Ruiter, Eva; Haferlach, C.; Beverloo, H. Berna; Costa, Delfina; Espinet Solà, Blanca; Foot, N.; Jeffries, S.; Martin, K.; O’Connor, S.; Schoumans, Jacqueline; Talley, P.; Telford, N.; Stioui, S.; Zemanova, Zuzana; Hastings, Rosalind J. (Frontiers, 2019)Cytogenomic investigations of haematological neoplasms, including chromosome banding analysis, fluorescence in situ hybridisation (FISH) and microarray analyses have become increasingly important in the clinical management ...
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Rack, K.A.; van den Berg-de-Ruiter, Eva; Haferlach, C.; Beverloo, H. Berna; Costa, Delfina; Espinet Solà, Blanca; Foot, N.; Jeffries, S.; Martin, K.; O’Connor, S.; Schoumans, Jacqueline; Talley, P.; Telford, N.; Stioui, S.; Zemanova, Zuzana; Hastings, Rosalind J. (Nature Research, 2020)
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Carracedo, Alma; Egervari, Kristof; Salido, Marta; Rojo, Federico; Arumí, Montserrat; Corominas Torres, Josep Maria; Corzo, Cristina; Tusquets Trias de Bes, Ignacio; Espinet Solà, Blanca; Rovira Guerín, Ana; Albanell Mestres, Joan; Szollosi, Zoltan; Serrano Figueras, Sergi; Solé Ristol, Francesc (BioMed Central, 2009)
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Hastings, Rosalind J.; Bown, Nick; Tibiletti, Maria G.; Debiec-Rychter, Maria; Vanni, Roberta; Espinet Solà, Blanca; van Roy, Nadine; Roberts, Paul; van den Berg-de-Ruiter, Eva; Bernheim, Alain; Schoumans, Jacqueline; Chatters, Steve; Zemanova, Zuzana; Stevens-Kroef, Marian; Simons, Annet; Heim, Sverre; Salido Galeote, Marta; Ylstra, Bauke; Betts, David R. (Nature publishing group, 2016)
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Prasad, Aparna; Rabionet, Raquel; Espinet Solà, Blanca; Zapata Ortiz, Luis, 1985-; Puiggros Metje, Anna Maria; Melero Vilella, Maria Carme; Puig, Anna; Sarria-Trujillo, Yaris; Ossowski, Stephan; Garcia-Muret, Maria P.; Estrach, Teresa; Servitje, Octavio; Lopez-Lerma, Ingrid; Gallardo Hernández, Fernando; Pujol Vallverdú, Ramon Maria; Estivill, Xavier, 1955- (Elsevier, 2016)Sézary syndrome is a leukemic form of cutaneous T-cell lymphoma with an aggressive clinical course. The genetic etiology of the disease is poorly understood, with chromosomal abnormalities and mutations in some genes being ...
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García-Martínez, Pablo; Sitjas, Dolors; Llistosella, Enric; Espinet Solà, Blanca; Rodríoguez Rivera, María; Gallardo Hernández, Fernando; Pujol Vallverdú, Ramon Maria (Society for Publication of Acta Dermato-Venereologica, 2017)Peripheral blood eosinophilia has been reported to occur in a wide range of haematological malignancies including primary cutaneous lymphomas. The concurrence of lymphomatoid papulosis (LyP) with peripheral blood eosinophilia ...
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Blanco, Gonzalo; Puiggros Metje, Anna Maria; Rodríguez-Rivera, María; Gimeno Vázquez, Eva; Abella Monreal, Eugenia; Ferrer Del Alamo, Ana; Espinet Solà, Blanca (Impact Journals, 2016)Patients with chronic lymphocytic leukemia (CLL) harboring TP53 aberrations (TP53abs; chromosome 17p deletion and/or TP53 mutation) exhibit an unfavorable clinical outcome. Chromosome 8 abnormalities, namely losses of 8p ...
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Casadevall Aguilar, David; Gimeno Beltran, Javier; Clavé Safont, Sergi; Taus García, Álvaro; Pijuan Andujar, Lara; Arumí de Dios, Miriam; Lorenzo Perez, Marta; Menendez Romero, Silvia; Cañadas Castillo, Israel, 1984-; Albanell Mestres, Joan; Serrano Figueras, Sergi; Espinet Solà, Blanca; Salido Galeote, Marta; Arriola Aperribay, Edurne (Impact Journals, 2015)OBJECTIVE: We aimed to assess MET intratumoral heterogeneity and its potential impact on biomarker-based patient selection as well as potential surrogate biomarkers of MET activation. METHODS: Our study included 120 patients ...
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Toll Abelló, Agustín; Salgado, Rocío; Espinet Solà, Blanca; Díaz-Lagares, Angel; Hernández-Ruiz, Eugenia; Andrades, Evelyn; Sandoval, Juan; Esteller, Manel; Pujol Vallverdú, Ramon Maria; Hernández-Muñoz, Inmaculada (BioMed Central, 2016)BACKGROUND: squamous cell carcinoma (cSCC) is the second most common skin cancer and frequently progresses from an actinic keratosis (AK), a sun-induced keratinocyte intraepithelial neoplasia (KIN). Epigenetic mechanisms ...
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García Gisbert, Nieves, 1994-; Garcia-Ávila, Sara; Merchán, Brayan; Salido Galeote, Marta; Fernández Rodríguez, M. Concepción; Gibert Fernandez, Joan 1988-; Fernández-Ibarrondo, Lierni; Camacho Díaz, Laura; Lafuente, Marta; Longarón Rozalen, Raquel; Espinet Solà, Blanca; Vélez, Patricia; Pujol Vallverdú, Ramon Maria; Andrade-Campos, Marcio; Arenillas Rocha, Leonor; Salar Silvestre, Antonio; Calvo Gonzalo, Xavier; Besses Raebel, Carles; Bellosillo Paricio, Beatriz (American Society of Hematology, 2022)Molecular and cytogenetic studies are essential for diagnosis and prognosis in patients with myelodysplastic syndromes (MDSs). Cell-free DNA (cfDNA) analysis has been reported to be a reliable noninvasive approach for ...
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Blanco Ares, Gonzalo, 1989- (Universitat Pompeu Fabra, 2017-12-01)The analysis of the microenvironment in CLL-like monoclonal B cell lymphocytosis (MBL) and early-stage chronic lymphocytic leukemia (CLL) is relevant for understanding the natural history of CLL. To this end, a total of ...
Now showing items 1-20 of 32
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