Browsing by Author "Dopazo, Joaquín"

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  • Dopazo, Joaquín; Rodríguez, Juan Antonio; Daub, Josephine T.; Muntané, Gerard; Navarro i Cuartiellas, Arcadi, 1969-; Antiñolo, Guillermo (Oxford University Press, 2016)
    Recent results from large-scale genomic projects suggest that allele frequencies, which are highly relevant for medical purposes, differ considerably across different populations. The need for a detailed catalog of local ...
  • Lagarde, Julien; Uszczynska-Ratajczak, Barbara; Santoyo-Lopez, Javier; Gonzalez, Jose Manuel; Tapanari, Electra; Mudge, Jonathan M.; Steward, Charles A.; Wilming, Laurens; Tanzer, Andrea; Howald, Cédric; Chrast, Jacqueline; Vela-Boza, Alicia; Rueda, Antonio; Lopez-Domingo, Francisco J.; Dopazo, Joaquín; Reymond, Alexandre; Guigó Serra, Roderic; Harrow, Jennifer (Nature Publishing Group, 2016)
    Long non-coding RNAs (lncRNAs) constitute a large, yet mostly uncharacterized fraction of the mammalian transcriptome. Such characterization requires a comprehensive, high-quality annotation of their gene structure and ...
  • Bleda Latorre, Marta, 1986- (Universitat Pompeu Fabra, 2015-11-27)
    Gene regulation is a complex biological process that requires the coordinated interaction of different molecules. The integrity of the underlying mechanisms ensures the correct expression of genes that maintain cell ...
  • Hidalgo, Marta R.; Amadoz, Alicia; Çubut, Cankut; Carbonell-Caballero, Jose; Dopazo, Joaquín (BioMed Central, 2018)
    Background: Despite the progress in neuroblastoma therapies the mortality of high-risk patients is still high (40–50%) and the molecular basis of the disease remains poorly known. Recently, a mathematical model was used ...
  • Torre, Iratxe; González-Tendero, Anna; García Cañadilla, Patricia, 1985-; Crispi Brillas, Fàtima; García-García, Francisco; Bijnens, Bart; Iruretagoyena, Igor; Dopazo, Joaquín; Amat-Roldán, Iván; Gratacós Solsona, Eduard (Public Library of Science, 2014)
    Background: Intrauterine growth restriction (IUGR) induces fetal cardiac remodelling and dysfunction, which persists postnatally and may explain the link between low birth weight and increased cardiovascular mortality in ...
  • Al-Shahrour, Fátima; Minguez, Pablo; Marquès i Bonet, Tomàs, 1975-; Gazave, Elodie; Navarro i Cuartiellas, Arcadi, 1969-; Dopazo, Joaquín (Public Library of Science (PLoS), 2010)
    An increasing number of evidences show that genes are not distributed randomly across eukaryotic chromosomes, but rather in functional neighborhoods. Nevertheless, the driving force that originated and maintains such ...
  • Ferreira, Pedro G.; Muñoz-Aguirre, Manuel; Reverter Comes, Ferran; Godinho, Caio P. Sá; Sousa, Abel; Amadoz, Alicia; Sodaei, Reza; Hidalgo, Marta R.; Pervouchine, Dmitri D.; Carbonell-Caballero, Jose; Nurtdinov, Ramil; Breschi, Alessandra, 1988-; Amador, Raziel; Oliveira, Patrícia; Çubut, Cankut; Curado, Joao; Aguet, François; Oliveira, Carla; Dopazo, Joaquín; Sammeth, Michael; Ardlie, Kristin G.; Guigó Serra, Roderic (Nature Publishing Group, 2018)
    Post-mortem tissues samples are a key resource for investigating patterns of gene expression. However, the processes triggered by death and the post-mortem interval (PMI) can significantly alter physiologically normal RNA ...