Browsing by Author "Domingo Rodriguez, Laura, 1992-"

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  • A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction
    Domingo Rodriguez, Laura, 1992-; Ruiz de Azua, Iñigo; Domínguez, Eduardo; Senabre, Eric; Serra, Irene; Kummer, Sami, 1985-; Navandar, Mohit; Baddenhausen, Sarah; Hofmann, Clementine; Andero, Raül; Gerber, Susanne; Navarrete, Marta; Dierssen, Mara; Lutz, Beat; Martín García, Elena, 1975-; Maldonado, Rafael, 1961- (Nature Research, 2020)
    Food addiction is linked to obesity and eating disorders and is characterized by a loss of behavioral control and compulsive food intake. Here, using a food addiction mouse model, we report that the lack of cannabinoid ...
  • Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons drives overconsumption of palatable food and obesity
    Ruiz de Azua, Iñigo; Martín García, Elena, 1975-; Domingo Rodriguez, Laura, 1992-; Aparisi Rey, Alejandro; Pascual Cuadrado, Diego; Islami, Larglinda; Turunen, Petri; Remmers, Floortje; Lutz, Beat; Maldonado, Rafael, 1961- (Nature Research, 2021)
    Palatable food can promote overfeeding beyond homeostatic requirements, thereby constituting a major risk to obesity. Here, the lack of cannabinoid type 1 receptor (CB1) in dorsal telencephalic glutamatergic neurons ...
  • Cell-type- and region-specific modulation of cocaine seeking by micro-RNA-1 in striatal projection neurons
    Forget, Benoit; Martin Garcia, Elena; Godino, Arthur; Domingo Rodriguez, Laura, 1992-; Kappes, Vincent; Poirier, Pierre; Andrianarivelo, Andry; Senabre, Eric; Allichon, Marie-Charlotte; Marias, Mélanie; Vanhoutte, Peter; Girault, Jean-Antoine; Maldonado, Rafael, 1961-; Caboche, Jocelyne (Nature Research, 2022)
    The persistent and experience-dependent nature of drug addiction may result in part from epigenetic alterations, including non-coding micro-RNAs (miRNAs), which are both critical for neuronal function and modulated by ...
  • Differential expression of miR-1249-3p and miR-34b-5p between vulnerable and resilient phenotypes of cocaine addiction
    Domingo Rodriguez, Laura, 1992-; Cabana-Domínguez, Judit; Fernàndez-Castillo, Noèlia; Cormand, Bru; Martín García, Elena, 1975-; Maldonado, Rafael, 1961- (Wiley, 2022)
    Cocaine addiction is a complex brain disorder involving long-term alterations that lead to loss of control over drug seeking. The transition from recreational use to pathological consumption is different in each individual, ...
  • Genomics and epigenomics of addiction
    Maldonado, Rafael, 1961-; Calvé Pérez, Pablo, 1993-; García Blanco, Alejandra; Domingo Rodriguez, Laura, 1992-; Senabre, Eric; Martín García, Elena, 1975- (Wiley, 2021)
    Recent progress in the genomics and epigenomics of addiction has contributed to improving our understanding of this complex mental disorder's etiology, filling the gap between genes, environment, and behavior. We review ...
  • miRNA signatures associated with vulnerability to food addiction in mice and humans
    García Blanco, Alejandra; Domingo Rodriguez, Laura, 1992-; Cabana-Domínguez, Judit; Fernández-Castillo, Noèlia; Pineda-Cirera, Laura; Mayneris Perxachs, Jordi; Burokas, Aurelijus, 1982-; Espinosa-Carrasco, José; Arboleya, Silvia; Latorre, Jessica; Stanton, Catherine; Cormand, Bru; Fernández Real, Jose M.; Martín-García, Elena; Maldonado, Rafael, 1961- (American Society for Clinical Investigation, 2022)
    Food addiction is characterized by a loss of behavioral control over food intake and is associated with obesity and other eating disorders. The mechanisms underlying this behavioral disorder are largely unknown. We aimed ...
  • Vulnerability to addiction
    Maldonado, Rafael, 1961-; Calvé Pérez, Pablo, 1993-; García Blanco, Alejandra; Domingo Rodriguez, Laura, 1992-; Senabre, Eric; Martín García, Elena, 1975- (Elsevier, 2021)
    Addiction is a chronic brain disease that has dramatic health and socioeconomic consequences worldwide. Multiple approaches have been used for decades to clarify the neurobiological basis of this disease and to identify ...

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