Browsing by Author "Domínguez, Orlando"

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  • Balbás Martínez, Cristina; Rodríguez Pinilla, María; Casanova, Ariel; Domínguez, Orlando; Pisano, David G.; Gómez López, Gonzalo; Lloreta, Josep, 1958-; Lorente Garin, José Antonio; Malats i Riera, Núria; Real, Francisco X. (Public Library of Science (PLoS), 2013)
    Urothelial bladder cancer (UBC) is heterogeneous at the clinical, pathological, genetic, and epigenetic levels. Exome sequencing has identified ARID1A as a novel tumor suppressor gene coding for a chromatin remodeling ...
  • Santos, Catarina P.; Lapi, Eleonora; Martínez de Villarreal, Jaime; Álvaro-Espinosa, Laura; Fernández Barral, Asunción; Barbáchano, Antonio; Domínguez, Orlando; Laughney, Ashley M.; Megías, Diego; Muñoz, Alberto; Real, Francisco X. (Nature Research, 2019)
    Understanding urothelial stem cell biology and differentiation has been limited by the lack of methods for their unlimited propagation. Here, we establish mouse urothelial organoids that can be maintained uninterruptedly ...
  • Fernández Barral, Asunción; Costales-Carrera, Alba; Buira, Sandra P.; Jung, Peter; Ferrer Mayorga, Gemma; Larriba, María Jesús; Bustamante Madrid, Pilar; Domínguez, Orlando; Real, Francisco X.; Guerra Pastrián, Laura; Lafarga, Miguel; García-Olmo, Damián; Cantero, Ramón; Del Peso, Luis; Batlle Gómez, Eduard; Rojo, Federico; Muñoz, Alberto; Barbáchano, Antonio (Wiley-Blackwell, 2019)
    Intestine is a major target of vitamin D and several studies indicate an association between vitamin D deficiency and inflammatory bowel diseases (IBD), but also increased colorectal cancer (CRC) risk and mortality. However, ...
  • Ferreiro Neira, Isabel; Joaquin i Caudet, Manel; Islam, Abul, 1978-; Gómez López, Gonzalo; Barragan, Montserrat; Lombardía, Luís; Domínguez, Orlando; Pisano, David G.; López Bigas, Núria; Nebreda, Ángel R.; Posas Garriga, Francesc (BioMed Central, 2010)
    Background: Cells have the ability to respond and adapt to environmental changes through activation of stress-activated protein kinases (SAPKs). Although p38 SAPK signalling is known to participate in the regulation of ...

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