Browsing by Author "Dobaño, Carlota"

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  • Ambient air pollution in relation to SARS-CoV-2 infection, antibody response, and COVID-19 disease: a Cohort study in Catalonia, Spain (COVICAT Study)
    Kogevinas, Manolis; Castaño Vinyals, Gemma; Karachaliou, Marianna; Espinosa Díaz, Ana; Garcia Aymerich, Judith; Jiménez, Alfons; Vidal, Marta; O’Callaghan-Gordo, Cristina; Cirach, Marta; Santano, Rebeca; Barrios, Diana; Puyol, Laura; Rubio, Rocío; Izquierdo, Luis; Nieuwenhuijsen, Mark J.; Dadvand, Payam; Aguilar, Ruth; Moncunill, Gemma; Dobaño, Carlota; Tonne, Cathryn (National Institute of Environmental Health Sciences (NIEHS), 2021)
    Background: emerging evidence links ambient air pollution with coronavirus 2019 (COVID-19) disease, an association that is methodologically challenging to investigate. Objectives: we examined the association between long-term ...
  • Antibody conversion rates to SARS-CoV-2 in saliva from children attending summer schools in Barcelona, Spain
    Dobaño, Carlota; Rodrigo Melero, Natalia; Carolis, Carlo; Jordan, Iolanda (BioMed Central, 2021)
    Background: Surveillance tools to estimate viral transmission dynamics in young populations are essential to guide recommendations for school opening and management during viral epidemics. Ideally, sensitive techniques are ...
  • Assessment of exposure to DDT and metabolites after indoor residual spraying through the analysis of thatch material from rural African dwellings
    Manaca, Maria Nélia Joquim, 1980-; Grimalt Obrador, Joan; Garí de Barbarà, Mercè, 1982-; Sacarlal, Jahit; Sunyer Deu, Jordi; Gonzalez, Raquel; Dobaño, Carlota; Menéndez, Clara; Alonso, Pedro L. (Springer, 2012)
    INTRODUCTION: We report on the analysis of 4,4'-dichlorodiphenyltrichloroethane (4,4'-DDT) and its metabolites in thatch and branch samples constituting the wall materials of dwellings from South African subtropical areas. ...
  • Assessment of the Combined Effect of Epstein-Barr Virus and Plasmodium falciparumInfections on Endemic Burkitt Lymphoma Using a Multiplex Serological Approach
    Aguilar, Ruth; Casabonne, Delphine; O’Callaghan-Gordo, Cristina; Vidal, Marta; Campo, Joseph J.; Mutalima, Nora; Angov, Evelina; Dutta, Sheetij; Gaur, Deepak; Chitnis, Chetan E.; Chauhan, Virander; Michel, Angelika; de Sanjosé, Silvia; Waterboer, Tim; Kogevinas, Manolis; Newton, Rob; Dobaño, Carlota (Frontiers, 2017)
    Epstein-Barr virus (EBV) is a necessary cause of endemic Burkitt lymphoma (eBL), while the role of Plasmodium falciparum in eBL remains uncertain. This study aimed to generate new hypotheses on the interplay between both ...
  • Determinants of early antibody responses to COVID-19 mRNA vaccines in a cohort of exposed and naïve healthcare workers
    Moncunill, Gemma; Aguilar, Ruth; Ribes, Marta; Ortega, Natalia; Rubio, Rocío; Molina, María José; Vidal, Marta; Barrios, Diana; Mitchell, Robert A.; Jiménez, Alfons; Castellana, Cristina; Rodó, Pau; Méndez, Susana; Llupià, Anna; Puyol, Laura; Rodrigo Melero, Natalia; Carolis, Carlo; Mayor, Alfredo; Izquierdo, Luis; Trilla, Antoni; Vilella, Anna; García-Basteiro, Alberto L.; Dobaño, Carlota (Elsevier, 2022)
    Background: Two doses of mRNA vaccination have shown >94% efficacy at preventing COVID-19 mostly in naïve adults, but it is not clear if the second dose is needed to maximize effectiveness in those previously exposed to ...
  • Disruption of cellular immune response among male rotating night shift workers in Spain- The HORMONIT study
    Harding, Barbara N.; Aguilar, Ruth; Espinosa Díaz, Ana; Castaño Vinyals, Gemma; Papantoniou, Kyriaki, 1983-; Navarrete, José María; Such Faro, Patricia; Torrejón, Antonio; Dobaño, Carlota; Moncunill, Gemma; Kogevinas, Manolis (Frontiers, 2022)
    Introduction: Preliminary studies suggest that night shift work is associated with a desynchronization of rhythmic immune markers, possibly explaining the increased risk of infection, cardiometabolic disorders, and cancer ...
  • Exposure to organochlorine compounds at the aerly stages of DDT use for indoor residual spraying in domestic environments in Manhiça, Mozambique.
    Manaca, Maria Nélia Joquim (Universitat Pompeu Fabra, 2011-09-27)
    Past and present uses of DDT and pyrethroids have led to their incorporation into humans, mainly through the food chain and sometimes by direct exposure. The present work focuses on establishing the levels of DDT, its ...
  • Genetic and epigenetic regulation of YKL-40 in childhood
    Guerra, Stefano; Sunyer Deu, Jordi; Lavi, Iris; Benet, Marta; Bustamante Pineda, Mariona; Carsin, Anne-Elie; Dobaño, Carlota; Guxens Junyent, Mònica; Tischer, Christina; Vrijheid, Martine; Antó i Boqué, Josep Maria; Koppelman, Gerard H. (Elsevier, 2018)
    Background: Circulating levels of the chitinase-like protein YKL-40 are influenced by genetic variation in its encoding gene (chitinase 3–like 1 [CHI3L1]) and are increased in patients with several diseases, including ...
  • Individual blood concentrations of persistent organic pollutants and chemical elements, and COVID-19: A prospective cohort study in Barcelona
    Porta Serra, Miquel; Pumarega Rodríguez, José Antonio; Gasull Panadès, Magda; Aguilar, Ruth; Henríquez Hernández, Luis Alberto; Basagaña Flores, Xavier; Zumbado, Manuel; Villar García, Judit; Rius, Cristina; Mehta, Sneha; Vidal, Marta; Jiménez, Alfons; Campi, Laura; Lop Gros, Joan; Pérez Luzardo, Octavio L.; Dobaño, Carlota; Moncunill, Gemma (Elsevier, 2023)
    Background: There is wide, largely unexplained heterogeneity in immunological and clinical responses to SARS-CoV-2 infection. Numerous environmental chemicals, such as persistent organic pollutants (POPs) and chemical ...
  • Infection induced SARS-CoV-2 seroprevalence and heterogeneity of antibody responses in a general population cohort study in Catalonia Spain
    Karachaliou, Marianna; Moncunill, Gemma; Espinosa Díaz, Ana; Castaño Vinyals, Gemma; Jiménez, Alfons; Vidal, Marta; Santano, Rebeca; Barrios, Diana; Jiménez, Alfons; Puyol, Laura; Mayer, Leonie; Rubio, Rocío; O'Callaghan Gordo, Cristina; Fossati, Serena; Rivas, Ioar; Vrijheid, Martine; Izquierdo, Luis; Aguilar, Ruth; Basagaña Flores, Xavier; García Aymerich, Judith; Dobaño, Carlota; Kogevinas, Manolis (Nature Research, 2021)
    Sparse data exist on the complex natural immunity to SARS-CoV-2 at the population level. We applied a well-validated multiplex serology test in 5000 participants of a general population study in Catalonia in blood samples ...
  • Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile
    Rubio, Rocío; Aguilar, Ruth; Bustamante Pineda, Mariona; Muñoz, Erica; Vázquez-Santiago, Miquel; Santano, Rebeca; Vidal, Marta; Rodrigo Melero, Natalia; Parras, Daniel; Serra, Pau; Santamaria, Pere; Carolis, Carlo; Izquierdo, Luis; Gómez-Roig, María Dolores; Dobaño, Carlota; Moncunill, Gemma; Mazarico, Edurne (Frontiers, 2022)
    SARS-CoV-2 infected pregnant women are at increased risk of severe COVID-19 than non-pregnant women and have a higher risk of adverse pregnancy outcomes like intrauterine/fetal distress and preterm birth. However, little ...
  • Mental health and COVID-19 in a general population cohort in Spain (COVICAT study)
    Goldberg, Ximena; Castaño Vinyals, Gemma; Espinosa Díaz, Ana; Carreras, Anna; Liutsko, Liudmila; Sicuri, Elisa; Foraster Pulido, Maria, 1984-; O'Callaghan-Gordo, Cristina; Dadvand, Payam; Moncunill, Gemma; Dobaño, Carlota; Cortés, B.; Pleguezuelos, V.; Straif, Kurt; García Aymerich, Judith; Cid Ibeas, Rafael de; Cardis, Elisabeth; Kogevinas, Manolis (SpringerOpen, 2022)
    Purpose: mental health conditions may affect outcome of COVID-19 disease, while exposure to stressors during the pandemic may impact mental health. The purpose of this study was to examine these factors in relation to ...
  • Multiplex antibody analysis of IgM, IgA and IgG to SARS-CoV-2 in saliva and serum from infected children and their close contacts
    Dobaño, Carlota; Alonso, Selena; Vidal, Marta; Jiménez, Alfons; Rubio, Rocío; Santano, Rebeca; Barrios, Diana; Puyol, Laura; Baró, Bàrbara; Millat-Martínez, Pere; Ajanovic, Sara; Balanza, Núria; Arias, Sara; Rodrigo Melero, Natalia; Carolis, Carlo; Bassat, Quique; Izquierdo, Luis; Aguilar, Ruth; Moncunill, Gemma (Frontiers, 2022)
    COVID-19 affects children to a lesser extent than adults but they can still get infected and transmit SARS-CoV-2 to their contacts. Field deployable non-invasive sensitive diagnostic techniques are needed to evaluate the ...
  • Persistence and baseline determinants of seropositivity and reinfection rates in health care workers up to 12.5 months after COVID-19
    Dobaño, Carlota; Ramírez-Morros, Anna; Alonso, Selena; Vidal Alaball, Josep; Ruiz-Olalla, Gemma; Vidal, Marta; Rubio, Rocío; Cascant, Emma; Parras, Daniel; Rodrigo Melero, Natalia; Serra, Pau; Carolis, Carlo; Santamaria, Pere; Forcada, Anna; Mendioroz Peña, Jacobo; Aguilar, Ruth; Moncunill, Gemma; Ruiz-Comellas, Anna (BioMed Central, 2021)
    We assessed the duration and baseline determinants of antibody responses to SARS-CoV-2 spike antigens and the occurrence of reinfections in a prospective cohort of 173 Spanish primary health care worker patients followed ...
  • RBD-Based ELISA and luminex predict Anti-SARS-CoV-2 surrogate-neutralizing activity in two longitudinal cohorts of German and Spanish health care workers
    Aguilar, Ruth; Vidal, Marta; Rubio, Rocío; Jiménez, Alfons; Carolis, Carlo; Mayor, Alfredo; Izquierdo, Luis; Garcia Basteiro, Alberto L.; Moncunill, Gemma; Dobaño, Carlota; Gerhard, Markus (American Society for Microbiology, 2023)
    The ability of antibodies to neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important correlate of protection. For routine evaluation of protection, however, a simple and cost-efficient ...
  • Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a prospective study
    Guerra, Stefano; Halonen, Marilyn; Vasquez, Monica M.; Spangenberg, Amber; Stern, Debra A.; Morgan, Wayne J.; Wright, Anne L.; Carsin, Anne-Elie; Dobaño, Carlota; Barreiro Portela, Esther; Zock, Jan-Paul; Martínez-Moratalla, Jesús; Sunyer Deu, Jordi; Antó i Boqué, Josep Maria; Martinez, Fernando D. (Elsevier, 2015)
    BACKGROUND: Low concentrations of the anti-inflammatory protein CC16 (approved symbol SCGB1A1) in serum have been associated with accelerated decline in forced expiratory volume in 1 s (FEV1) in patients with chronic ...
  • SARS-CoV-2 infection, vaccination, and antibody response trajectories in adults: a cohort study in Catalonia
    Karachaliou, Marianna; Moncunill, Gemma; Espinosa Díaz, Ana; Castaño Vinyals, Gemma; Rubio, Rocío; Vidal, Marta; Jiménez, Alfons; Prados, Esther; Bañuls, Marc; Melero, Natalia Rodrigo; Izquierdo, Luis; Carolis, Carlo; Goldberg, Ximena; Aguilar, Ruth; García Aymerich, Judith; Kogevinas, Manolis; Dobaño, Carlota (BioMed Central, 2022)
    Background: Heterogeneity of the population in relation to infection, COVID-19 vaccination, and host characteristics is likely reflected in the underlying SARS-CoV-2 antibody responses. Methods: We measured IgM, IgA, and ...
  • SARS-CoV-2 seroprevalence study in pediatric patients and health care workers using multiplex antibody immunoassays
    Prados de la Torre, Esther; Obando, Ignacio; Vidal, Marta; Felipe, Beatriz de; Aguilar, Ruth; Izquierdo, Luis; Carolis, Carlo; Olbrich, Peter; Capilla-Miranda, Ana; Serra, Pau; Santamaria, Pere; Blanco-Lobo, Pilar; Moncunill, Gemma; Rodríguez-Ortega, Manuel J.; Dobaño, Carlota (MDPI, 2022)
    SARS-CoV-2 infection has become a global health problem specially exacerbated with the continuous appearance of new variants. Healthcare workers (HCW) have been one of the most affected sectors. Children have also been ...
  • Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital
    Garcia Basteiro, Alberto L.; Carolis, Carlo; Hecht, Jochen; Dobaño, Carlota (Nature Research, 2020)
    Health care workers (HCW) are a high-risk population to acquire SARS-CoV-2 infection from patients or other fellow HCW. This study aims at estimating the seroprevalence against SARS-CoV-2 in a random sample of HCW from a ...
  • Seven-month kinetics of SARS-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses
    Ortega, Natalia; Ribes, Marta; Vidal, Marta; Rubio, Rocío; Aguilar, Ruth; Williams, Sarah; Barrios, Diana; Alonso, Selena; Mitchell, Robert A.; Jairoce, Chenjerai; Cruz, Angeline; Jimenez, Alfons; Santano, Rebeca; Méndez, Susana; Lamoglia, Montserrat; Rosell, Neus; Llupià, Anna; Puyol, Laura; Chi, Jordi; Rodrigo Melero, Natalia; Mayor, Alfredo; Vilella, Anna; Trilla, Antoni; Carolis, Carlo; Izquierdo, Luis; García-Basteiro, Alberto L.; Moncunill, Gemma; Dobaño, Carlota (Nature Research, 2021)
    Unraveling the long-term kinetics of antibodies to SARS-CoV-2 and the individual characteristics influencing it, including the impact of pre-existing antibodies to human coronaviruses causing common cold (HCoVs), is essential ...