Browsing by Author "Desco, Manuel"

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  • A method for small-animal PET/CT alignment calibration. Physics in medicine & biology
    Pascau, Javier; Vaquero, Juan J.; Chamorro Servent, Judit; Rodríguez-Ruano, A.; Desco, Manuel (Institute of Physics (IOP), 2012)
    Small-animal positron-emission tomography/computed tomography (PET/ CT) scanners provide anatomical and molecular imaging, which enables the joint visualization and analysis of both types of data. A proper alignment ...
  • Automated method for small-animal PET image registration with intrinsic validation
    Pascau, Javier; Gispert López, Juan Domingo; Michaelides, Michael; Thanos, Panayotis K.; Volkow, Nora D.; Vaquero, Juan J.; Soto-Montenegro, Maria Luisa; Desco, Manuel (Springer, 2009)
    PURPOSE: We propose and compare different registration approaches to align small-animal PET studies and a procedure to validate the results by means of objective registration consistency measurements. PROCEDURES: We have ...
  • Becoming a mother entails anatomical changes in the ventral striatum of the human brain that facilitate its responsiveness to offspring cues
    Hoekzema, Elseline; Tamnes, Christian K.; Berns, Puck; Barba-Müller, Erika; Pozzobon, Cristina; Picado, Marisol; Lucco, Florencio; Martínez-García, Magdalena; Desco, Manuel; Ballesteros, Agustín; Crone, Eveline A.; Vilarroya, Óscar; Carmona, Susanna (Elsevier, 2020)
    In mothers, offspring cues are associated with a powerful reinforcing value that motivates maternal care. Animal studies show that this is mediated by dopamine release into the nucleus accumbens, a core component of the ...
  • Characterizing the brain structural adaptations across the motherhood transition
    Martínez-García, Magdalena; Paternina Die, María; Desco, Manuel; Vilarroya, Óscar; Carmona, Susanna (Frontiers, 2021)
    Women that become mothers face notable physiological adaptations during this life-period. Neuroimaging studies of the last decade have provided grounded evidence that women's brains structurally change across the transition ...
  • Do pregnancy-induced brain changes reverse? The brain of a mother six years after parturition
    Martínez-García, Magdalena; Paternina Die, María; Barba-Müller, Erika; Martín de Blas, Daniel; Beumala, Laura; Cortizo Vidal, Romina; Pozzobon, Cristina; Marcos-Vidal, Luis; Fernández Pena, Alberto; Picado, Marisol; Belmonte Padilla, Elena; Massó Rodriguez, Anna; Ballesteros, Agustín; Desco, Manuel; Vilarroya, Óscar; Hoekzema, Elseline; Carmona, Susanna (MDPI, 2021)
    Neuroimaging researchers commonly assume that the brain of a mother is comparable to that of a nulliparous woman. However, pregnancy leads to pronounced gray matter volume reductions in the mother's brain, which have been ...
  • Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate
    Michaelides, Michael; Pascau, Javier; Gispert López, Juan Domingo; Delis, Foteini; Grandy, David K.; Wang, Gene-Jack; Desco, Manuel; Rubinstein, Marcelo; Wolkow, Nora D.; Thanos, Panayotis K. (Wiley-VCH Verlag, 2010)
    Methylphenidate (MP) is widely used to treat attention deficit hyperactivity disorder (ADHD). Variable number of tandem repeats polymorphisms in the dopamine D4 receptor (D(4)) gene have been implicated in vulnerability ...
  • FDOT reconstruction and setting optimization using singular value analysis with automatic thresholding
    Chamorro Servent, Judit; Aguirre, Juan; Ripoll, Jorge; Vaquero, Juan J.; Desco, Manuel (Institute of Electrical and Electronics Engineers (IEEE), 2009)
    Fluorescence Enhanced Diffuse Optical Tomography (FDOT) retrieves 3D distributions of fluorophore concentration in small animals, non-invasively and in vivo. The FDOT problem can be formulated as a system of equations, ...
  • Feasibility of U-curve method to select the regularization parameter for fluorescence diffuse optical tomography in phantom and small animal studies
    Chamorro Servent, Judit; Aguirre, Juan; Ripoll, Jorge; Vaquero, Juan J.; Desco, Manuel (Optical Society of America (OSA), 2011)
    When dealing with ill-posed problems such as fluorescence diffuse optical tomography (fDOT) the choice of the regularization parameter is extremely important for computing a reliable reconstruction. Several automatic methods ...
  • Fluorescence diffuse optical tomography using the split Bregman method
    Abascal, Juan Felipe Pérez Juste; Chamorro Servent, Judit; Aguirre, Juan; Arridge, Simon; Correia, Teresa; Ripoll, Jorge; Vaquero, Juan J.; Desco, Manuel (American Association of Physicists in Medicine, 2011)
    Purpose: Standard image reconstruction methods for fluorescence Diffuse Optical Tomography (fDOT) generally make use of L2-regularization. A better choice is to replace the L2 by a total variation functional that effectively ...
  • High-resolution dynamic cardiac MRI on small animals using reconstruction based on Split Bregman methodology
    Montesinos, P.; Abascal, Juan Felipe Pérez Juste; Chamorro Servent, Judit; Chavarrías, Cristina; Benito, M.; Vaquero, Juan J.; Desco, Manuel (Institute of Electrical and Electronics Engineers (IEEE), 2011)
    Dynamic cardiac magnetic resonance imaging in small animals is an important tool in the study of cardiovascular diseases. The reduction of the long acquisition times required for cardiovascular applications is crucial to ...
  • ITEMAS ontology for healthcare technology innovation
    Moreno-Conde, A.; Parra-Calderón, C.L.; Sánchez-Seda, S.; Escobar-Rodríguez, G. A.; López Otero, Marta; Cussó, L.; Del-Cerro-García, R.; Segura-Sánchez, M.; Herrero-Urigüen, L.; Martí-Ras, N.; Albertí-Ibarz, M.; Desco, Manuel (BioMed Central, 2019)
    Background: The Platform for Innovation in Medical and Health Technologies (ITEMAS) is a network of 66 healthcare centres focused on fostering innovation in medical and health technologies as an essential tool for increasing ...
  • Sensory-to-cognitive systems integration is associated with clinical severity in autism spectrum disorder
    Martínez, Kenia; Martínez-García, Magdalena; Marcos-Vidal, Luis; Janssen, Joost; Castellanos, Francisco X.; Petrus, Clara; Vilarroya, Óscar; Pina-Camacho, Laura; Díaz-Caneja, Covadonga M.; Parellada, Mara; Arango, Celso; Desco, Manuel; Sepulcre, Jorge; Carmona, Susanna (Elsevier, 2020)
    Objective: Impaired multisensory integration in autism spectrum disorder (ASD) may arise from functional dysconnectivity among brain systems. Our study examines the functional connectivity integration between primary modal ...
  • Split operator method for fluorescence diffuse optical tomography using anisotropic diffusion regularisation with prior anatomical information
    Correia, Teresa; Aguirre, Juan; Sisniega, Alejandro; Chamorro Servent, Judit; Abascal, Juan Felipe Pérez Juste; Vaquero, Juan J.; Desco, Manuel; Arridge, Simon (Optical Society of America (OSA), 2011)
    Fluorescence diffuse optical tomography (fDOT) is an imaging modality that provides images of the fluorochrome distribution within the object of study. The image reconstruction problem is ill-posed and highly underdetermined ...
  • Stepwise functional connectivity reveals altered sensory-multimodal integration in medication-naïve adults with attention deficit hyperactivity disorder
    Petrus, Clara; Marcos-Vidal, Luis; Martínez-García, Magdalena; Picado, Marisol; Ramos-Quiroga; Josep Antoni; Richarte, Vanesa; Castellanos, Francisco X.; Sepulcre, Jorge; Desco, Manuel; Vilarroya, Óscar; Carmona, Susanna (Wiley, 2019)
    Neuroimaging studies indicate that children with attention-deficit/hyperactivity disorder (ADHD) present alterations in several functional networks of the sensation-to-cognition spectrum. These alterations include functional ...
  • The paternal transition entails neuroanatomic adaptations that are associated with the father's brain response to his infant cues
    Paternina Die, María; Martínez-García, Magdalena; Pretus, Clara; Hoekzema, Elseline; Barba-Müller, Erika; Martín de Blas, Daniel; Pozzobon, Cristina; Ballesteros, Agustín; Vilarroya, Óscar; Desco, Manuel; Carmona, Susanna (Oxford University Press, 2020)
    The transition into fatherhood is a life-changing event that requires substantial psychological adaptations. In families that include a father figure, sensitive paternal behavior has been shown to positively impact the ...
  • Use of Split Bregman denoising for iterative reconstruction in fluorescence diffuse optical tomography
    Chamorro Servent, Judit; Abascal, Juan Felipe Pérez Juste; Aguirre, Juan; Arridge, Simon; Correia, Teresa; Ripoll, Jorge; Desco, Manuel; Vaquero, Juan J. (Society of Photo Optical Instrumentation Engineers (SPIE), 2013)
    Fluorescence diffuse optical tomography (fDOT) is a noninvasive imaging technique that makes it possible to quantify the spatial distribution of fluorescent tracers in small animals. fDOT image reconstruction is commonly ...
  • Women's neuroplasticity during gestation, childbirth and postpartum
    Paternina Die, María; Martínez-García, Magdalena; Martín de Blas, Daniel; Noguero, Inés; Servin Barthet, Camila; Pretus, Clara; Soler Campillo, Anna; López Montoya, Gonzalo; Desco, Manuel; Carmona, Susanna (Nature Research, 2024)
    Pregnancy is a unique neuroplastic period in adult life. This longitudinal study tracked brain cortical changes during the peripartum period and explored how the type of childbirth affects these changes. We collected ...

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