We propose a top-down approach to the symptoms of schizophrenia based on a statistical dynamical framework. We show that a reduced depth in the basins of attraction of cortical attractor states destabilizes the activity ...

The role of changes of mind and multiple choices has recently received increased attention in the study of perceptual/ndecision-making. Previously, these extensions to standard two-alternative tasks have been studied ...

Cortical function emerges from the interactions of multi-scale networks that may be studied at a high level using neural mass models (NMM) that represent the mean activity of large numbers of neurons. Here, we provide first ...

Neurobiological models to explain vulnerability of major depressive disorder (MDD) are scarce and previous functional magnetic resonance imaging studies mostly examined “static” functional connectivity (FC). Knowing that ...

Intracranial electroencephalography (iEEG) is an invasive diagnostic procedure used in severe drug-resistant epilepsy patients that provides simultaneous recordings of multiple brain regions at a very high temporal resolution. ...

A fundamental problem in systems neuroscience is how to force a transition from one brain state to another by external driven stimulation in, for example, wakefulness, sleep, coma, or neuropsychiatric diseases. This requires ...

With the increasing availability of advanced imaging technologies, we are/nentering a new era of neuroscience. Detailed descriptions of the complex brain/nnetwork enable us to map out a structural connectome, characterize ...

This short survey reviews the recent literature on the relationship between the brain structure and its functional dynamics. Imaging techniques such as diffusion tensor imaging (DTI) make it possible to reconstruct axonal ...

A key unresolved problem in neuroscience is to determine the relevant timescale for understanding spatiotemporal dynamics across the whole brain. While resting state fMRI reveals networks at an ultraslow timescale (below ...

Spontaneous brain activity persists and transitions between brain states, such as from wakefulness to sleep, from development to ageing, or it may transition to pathological states such as coma. Nevertheless, a consensual ...