Browsing by Author "Dall'Olio, Giovanni Marco, 1983-"

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  • Pybus Oliveras, Marc, 1985-; Dall'Olio, Giovanni Marco, 1983-; Luisi, Pierre, 1985-; Uzkudun, Manu; Carreño Torres, Angel; Pavlidis, Pavlos; Laayouni, Hafid, 1968-; Bertranpetit, Jaume, 1952-; Engelken, Johannes (Oxford University Press, 2014)
    Searching for Darwinian selection in natural populations has been the focus of a multitude of studies over the last decades. Here we present the 1000 Genomes Selection Browser 1.0 (http://hsb.upf.edu) as a resource for ...
  • Dall'Olio, Giovanni Marco, 1983- (Universitat Pompeu Fabra, 2013-10-28)
    In this thesis we developed two approaches to study positive selection and genetic adaptation in the human genome. Both approaches are based on applications of network theory. In the first approach, we studied how the ...
  • Dall'Olio, Giovanni Marco, 1983-; Laayouni, Hafid, 1968-; Luisi, Pierre, 1985-; Sikora, Martin, 1976-; Montanucci, Ludovica, 1978-; Bertranpetit, Jaume, 1952- (BioMed Central, 2012)
    Asparagine N-Glycosylation is one of the most important forms of protein post-translational modification in eukaryotes. This metabolic pathway can be subdivided into two parts: an upstream sub-pathway required for achieving ...
  • Mondal, Mayukh, 1989-; Casals López, Ferran; Xu, Tina; Dall'Olio, Giovanni Marco, 1983-; Pybus Oliveras, Marc, 1985-; Netea, Mihai G; Comas, David, 1969-; Laayouni, Hafid, 1968-; Li, Qibin; Majumder, Partha P.; Bertranpetit, Jaume, 1952- (Nature Publishing Group, 2016)
    To shed light on the peopling of South Asia and the origins of the morphological adaptations found there, we analyzed whole-genome sequences from 10 Andamanese individuals and compared them with sequences for 60 individuals ...
  • Pybus Oliveras, Marc, 1985-; Luisi, Pierre, 1985-; Dall'Olio, Giovanni Marco, 1983-; Uzkudun, Manu; Laayouni, Hafid, 1968-; Bertranpetit, Jaume, 1952-; Engelken, Johannes (Oxford University Press, 2015)
    MOTIVATION: Detecting positive selection in genomic regions is a recurrent topic in natural population genetic studies. However, there is little consistency among the regions detected in several genome-wide scans using ...
  • Dall'Olio, Giovanni Marco, 1983-; Bertranpetit, Jaume, 1952-; Wagner, Andreas; Laayouni, Hafid, 1968- (Public Library of Science (PLoS), 2014)
    Genotype networks are a concept used in systems biology to study sets of genotypes having the same phenotype, and the ability of these to bring forth novel phenotypes. In the past they have been applied to determine the ...
  • Laayouni, Hafid, 1968-; Montanucci, Ludovica, 1978-; Sikora, Martin, 1976-; Melé Messeguer, Marta, 1982-; Dall'Olio, Giovanni Marco, 1983-; Lorente-Galdós, Belén, 1981-; McGee, Kate M; Graffelman, Jan; Awadalla, Philip; Bosch Fusté, Elena; Comas, David, 1969-; Navarro i Cuartiellas, Arcadi, 1969-; Calafell i Majó, Francesc; Casals López, Ferran; Bertranpetit, Jaume, 1952- (Public Library of Science (PLoS), 2011)
    Recombination varies greatly among species, as illustrated by the poor conservation of the recombination landscape between humans and chimpanzees. Thus, shorter evolutionary time frames are needed to understand the evolution ...
  • Dall'Olio, Giovanni Marco, 1983-; Bertranpetit, Jaume, 1952-; Laayouni, Hafid, 1968- (Oxford University Press, 2010)
    Since the publication of their longtime predecessor The Atlas of Protein Sequences and Structures in 1965 by Margaret Dayhoff, scientific databases have become a key factor in the organization of modern science. All the ...
  • Dall'Olio, Giovanni Marco, 1983-; Vahdati, Ali R.; Bertranpetit, Jaume, 1952-; Wagner, Andreas; Laayouni, Hafid, 1968- (Oxford University Press, 2015)
    SUMMARY: A wealth of large-scale genome sequencing projects opens the doors to new approaches to study the relationship between genotype and phenotype. One such opportunity is the possibility to apply genotype networks ...